lanosterol + 3 reduced [NADPH—hemoprotein reductase] + 3 O<small><sub>2</sub></small> => 4,4-dimethyl-5α-cholesta-8,14,24-trien-3β-ol + formate + 3 oxidized [NADPH—hemoprotein reductase] + 4 H<small><sub>2</sub></small>O + 4 H<small><sup>+</sup></small> - 数据之源，洞见之始

Rhea:RHEA:25287

Multi-step reaction: RHEA:75103 + RHEA:75107 + RHEA:75111

lanosterol + 3 reduced [NADPH—hemoprotein reductase] + 3 O₂ => 4,4-dimethyl-5α-cholesta-8,14,24-trien-3β-ol + formate + 3 oxidized [NADPH—hemoprotein reductase] + 4 H₂O + 4 H⁺

= Lanosterol[C30H50O] + [] + Oxygen[O2] + 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol[C29H46O] + Formate[CH2O2] + [] + H2O[H2O] + H+[H]

DB Links

BioCyc: RXN3O-130
EC Number: 1.14.14.154
Rhea: RHEA:25287

Alias

[Rhea:RHEA:25287] lanosterol + 3 reduced [NADPH—hemoprotein reductase] + 3 O₂ => 4,4-dimethyl-5α-cholesta-8,14,24-trien-3β-ol + formate + 3 oxidized [NADPH—hemoprotein reductase] + 4 H₂O + 4 H⁺
[Rhea:RHEA:25288] 4,4-dimethyl-5α-cholesta-8,14,24-trien-3β-ol + formate + 3 oxidized [NADPH—hemoprotein reductase] + 4 H₂O + 4 H⁺ => lanosterol + 3 reduced [NADPH—hemoprotein reductase] + 3 O₂
[Rhea:RHEA:25289] lanosterol + 3 reduced [NADPH—hemoprotein reductase] + 3 O₂ <=> 4,4-dimethyl-5α-cholesta-8,14,24-trien-3β-ol + formate + 3 oxidized [NADPH—hemoprotein reductase] + 4 H₂O + 4 H⁺

Metabolites

Substrates

metabolite	compartment	Structure

Products

metabolite	compartment	Structure
Lanosterol Formula: C30H50O	Cytoplasm
Formula:	Cytoplasm
Oxygen Formula: O2	Cytoplasm
4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol Formula: C29H46O	Cytoplasm
Formate Formula: CH2O2	Cytoplasm
Formula:	Cytoplasm
H2O Formula: H2O	Cytoplasm
H+ Formula: H	Cytoplasm