数据之源，洞见之始

3-O-(β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP + H⁺ => 3-O-(β-D-GlcA-(1→3)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine

= [] + UDP(3-)[C9H11N2O12P2] + H+[H] + [] + UDP-N-acetyl-alpha-D-galactosamine(2-)[C17H25N3O17P2]

DB Links

• EC Number: 2.4.1.175
• Rhea: RHEA:20802

Alias

• [Rhea:RHEA:20801] 3-O-(β-D-GlcA-(1→3)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine => 3-O-(β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP + H⁺
• [Rhea:RHEA:20802] 3-O-(β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP + H⁺ => 3-O-(β-D-GlcA-(1→3)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine
• [Rhea:RHEA:20803] 3-O-(β-D-GlcA-(1→3)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine <=> 3-O-(β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP + H⁺
• [Rhea:RHEA:23465] 3-O-(β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine => 3-O-(β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP + H⁺
• [Rhea:RHEA:23466] 3-O-(β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP + H⁺ => 3-O-(β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine
• [Rhea:RHEA:23467] 3-O-(β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine <=> 3-O-(β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl)-L-seryl-[protein] + UDP + H⁺
• [Rhea:RHEA:23957] L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine => a 3-O-[N-acetyl-α-D-galactosaminyl]-L-seryl-[protein] + UDP + H⁺
• [Rhea:RHEA:23958] a 3-O-[N-acetyl-α-D-galactosaminyl]-L-seryl-[protein] + UDP + H⁺ => L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine
• [Rhea:RHEA:23959] L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine <=> a 3-O-[N-acetyl-α-D-galactosaminyl]-L-seryl-[protein] + UDP + H⁺
• [Rhea:RHEA:37668] 3-O-(N-acetyl-β-D-glucosaminyl-(1→4)-α-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-α-D-galactosamine => 3-O-[β-D-GalNAc-(1→3)-β-D-GlcNAc-(1→4)-α-D-Man]-L-Thr-[protein] + UDP + H⁺
• [Rhea:RHEA:37669] 3-O-[β-D-GalNAc-(1→3)-β-D-GlcNAc-(1→4)-α-D-Man]-L-Thr-[protein] + UDP + H⁺ => 3-O-(N-acetyl-β-D-glucosaminyl-(1→4)-α-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-α-D-galactosamine
• [Rhea:RHEA:37670] 3-O-(N-acetyl-β-D-glucosaminyl-(1→4)-α-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-α-D-galactosamine <=> 3-O-[β-D-GalNAc-(1→3)-β-D-GlcNAc-(1→4)-α-D-Man]-L-Thr-[protein] + UDP + H⁺
• [Rhea:RHEA:52425] L-threonyl-[protein] + UDP-N-acetyl-α-D-galactosamine => a 3-O-[N-acetyl-α-D-galactosaminyl]-L-threonyl-[protein] + UDP + H⁺
• [Rhea:RHEA:52426] a 3-O-[N-acetyl-α-D-galactosaminyl]-L-threonyl-[protein] + UDP + H⁺ => L-threonyl-[protein] + UDP-N-acetyl-α-D-galactosamine
• [Rhea:RHEA:52427] L-threonyl-[protein] + UDP-N-acetyl-α-D-galactosamine <=> a 3-O-[N-acetyl-α-D-galactosaminyl]-L-threonyl-[protein] + UDP + H⁺
• [Rhea:RHEA:55001] 3-O-{β-D-GlcA-(1→3)-[β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)]_(n)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine => 3-O-{[β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)]_(n+1)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl}-L-seryl-[protein] + UDP + H⁺
• [Rhea:RHEA:55002] 3-O-{[β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)]_(n+1)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl}-L-seryl-[protein] + UDP + H⁺ => 3-O-{β-D-GlcA-(1→3)-[β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)]_(n)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine
• [Rhea:RHEA:55003] 3-O-{β-D-GlcA-(1→3)-[β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)]_(n)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine <=> 3-O-{[β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)]_(n+1)-β-D-GalNAc-(1→4)-β-D-GlcA-(1→3)-β-D-Gal-(1→3)-β-D-Gal-(1→4)-β-D-Xyl}-L-seryl-[protein] + UDP + H⁺
• [Rhea:RHEA:81956] a 3-O-{α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-[α-Neu5Ac-(2→6)]-α-D-GalNAc}-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine => a 3-O-{[α-Neu5Ac-(2→3)]-β-D-GalNAc-(1→4)-β-D-Gal-(1→3)-[α-Neu5Ac-(2→6)]-α-D-GalNAc}-L-seryl-[protein] + UDP + H⁺
• [Rhea:RHEA:81957] a 3-O-{[α-Neu5Ac-(2→3)]-β-D-GalNAc-(1→4)-β-D-Gal-(1→3)-[α-Neu5Ac-(2→6)]-α-D-GalNAc}-L-seryl-[protein] + UDP + H⁺ => a 3-O-{α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-[α-Neu5Ac-(2→6)]-α-D-GalNAc}-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine
• [Rhea:RHEA:81958] a 3-O-{α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-[α-Neu5Ac-(2→6)]-α-D-GalNAc}-L-seryl-[protein] + UDP-N-acetyl-α-D-galactosamine <=> a 3-O-{[α-Neu5Ac-(2→3)]-β-D-GalNAc-(1→4)-β-D-Gal-(1→3)-[α-Neu5Ac-(2→6)]-α-D-GalNAc}-L-seryl-[protein] + UDP + H⁺
• [Rhea:RHEA:81972] a 3-O-{α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-[α-Neu5Ac-(2→6)]-α-D-GalNAc}-L-threonyl-[protein] + UDP-N-acetyl-α-D-galactosamine => a 3-O-{[α-Neu5Ac-(2→3)]-β-D-GalNAc-(1→4)-β-D-Gal-(1→3)-[α-Neu5Ac-(2→6)]-α-D-GalNAc}-L-threonyl-[protein] + UDP + H⁺
• [Rhea:RHEA:81973] a 3-O-{[α-Neu5Ac-(2→3)]-β-D-GalNAc-(1→4)-β-D-Gal-(1→3)-[α-Neu5Ac-(2→6)]-α-D-GalNAc}-L-threonyl-[protein] + UDP + H⁺ => a 3-O-{α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-[α-Neu5Ac-(2→6)]-α-D-GalNAc}-L-threonyl-[protein] + UDP-N-acetyl-α-D-galactosamine
• [Rhea:RHEA:81974] a 3-O-{α-Neu5Ac-(2→3)-β-D-Gal-(1→3)-[α-Neu5Ac-(2→6)]-α-D-GalNAc}-L-threonyl-[protein] + UDP-N-acetyl-α-D-galactosamine <=> a 3-O-{[α-Neu5Ac-(2→3)]-β-D-GalNAc-(1→4)-β-D-Gal-(1→3)-[α-Neu5Ac-(2→6)]-α-D-GalNAc}-L-threonyl-[protein] + UDP + H⁺

Metabolites

Substrates

metabolite	compartment	Structure

Products

metabolite	compartment	Structure
Formula:	Cytoplasm
UDP(3-) Formula: C9H11N2O12P2	Cytoplasm
H+ Formula: H	Cytoplasm
Formula:	Cytoplasm
UDP-N-acetyl-alpha-D-galactosamine(2-) Formula: C17H25N3O17P2	Cytoplasm