Rhea:RHEA:19630

Multi-step reaction: RHEA:25588 and RHEA:19381

D-threo-isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH

= D-threo-isocitrate(3-)[C6H5O7] + NADP(3-)[C21H25N7O17P3] + 2-Oxoglutarate[C5H6O5] + CO2[CO2] + NADPH(4-)[C21H26N7O17P3]

DB Links

  • EC Number: 1.1.1.42
  • Rhea: RHEA:19630
  • Reactome: R-HSA-389540.5
  • Reactome: R-HSA-389550.3
  • Reactome: R-HSA-450984.6
  • MACiE: M0007
Alias

Metabolites

Substrates
metabolite compartment Structure
Products
metabolite compartment Structure
D-threo-isocitrate(3-)

Formula: C6H5O7		 Cytoplasm
NADP(3-)

Formula: C21H25N7O17P3		 Cytoplasm
2-Oxoglutarate

Formula: C5H6O5		 Cytoplasm
CO2

Formula: CO2		 Cytoplasm
NADPH(4-)

Formula: C21H26N7O17P3		 Cytoplasm