Nucleoplasm

The nucleoplasm is the semi-fluid, gel-like matrix within the nuclear envelope, distinct from the cytoplasm. It houses chromatin (DNA-protein complexes), the nucleolus, transcription factors, and essential enzymes. This compartment is critical for nuclear functions, including DNA replication, transcription, RNA processing, and DNA repair, while maintaining the structural organization and biochemical separation of the nucleus from the cytosol. Its composition and dynamics directly support genomic integrity and gene regulation.

View SubCellular Compartment Model

Protein List

ID name Taxonomy Function
P04786 TOP1 Saccharomyces cerevisiae S288C DNA topoisomerase 1
P04786 TOP1 Saccharomyces cerevisiae S288C DNA topoisomerase 1
P26793 RAD27 Saccharomyces cerevisiae S288C Flap endonuclease 1
P26793 RAD27 Saccharomyces cerevisiae S288C Flap endonuclease 1
P29295 HRR25 Saccharomyces cerevisiae S288C Casein kinase I homolog HRR25
P29295 HRR25 Saccharomyces cerevisiae S288C Casein kinase I homolog HRR25
Q12464 RVB2 Saccharomyces cerevisiae S288C RuvB-like protein 2
Q12464 RVB2 Saccharomyces cerevisiae S288C RuvB-like protein 2
A6ZZK4 RAD27 Saccharomyces cerevisiae YJM789 Flap endonuclease 1
A6ZZK4 RAD27 Saccharomyces cerevisiae YJM789 Flap endonuclease 1
A7TJ59 FEN1 Vanderwaltozyma polyspora DSM 70294 Flap endonuclease 1
A7TJ59 FEN1 Vanderwaltozyma polyspora DSM 70294 Flap endonuclease 1
B3LQY3 RAD27 Saccharomyces cerevisiae RM11-1a Flap endonuclease 1
B3LQY3 RAD27 Saccharomyces cerevisiae RM11-1a Flap endonuclease 1
C5DGG4 FEN1 Lachancea thermotolerans CBS 6340 Flap endonuclease 1
C5DGG4 FEN1 Lachancea thermotolerans CBS 6340 Flap endonuclease 1
C5DZA9 FEN1 Zygosaccharomyces rouxii CBS 732 Flap endonuclease 1
C5DZA9 FEN1 Zygosaccharomyces rouxii CBS 732 Flap endonuclease 1
C7GVJ8 RAD27 Saccharomyces cerevisiae JAY291 Flap endonuclease 1
C7GVJ8 RAD27 Saccharomyces cerevisiae JAY291 Flap endonuclease 1
C8ZC62 RAD27 Saccharomyces cerevisiae EC1118 Flap endonuclease 1
C8ZC62 RAD27 Saccharomyces cerevisiae EC1118 Flap endonuclease 1
Q6CLH4 FEN1 Kluyveromyces lactis NRRL Y-1140 Flap endonuclease 1
Q6CLH4 FEN1 Kluyveromyces lactis NRRL Y-1140 Flap endonuclease 1
Q6FM28 FEN1 Nakaseomyces glabratus CBS 138 Flap endonuclease 1
Q6FM28 FEN1 Nakaseomyces glabratus CBS 138 Flap endonuclease 1
Q75DS8 FEN1 Eremothecium gossypii ATCC 10895 Flap endonuclease 1
Q75DS8 FEN1 Eremothecium gossypii ATCC 10895 Flap endonuclease 1
A0A061AVA4 A0A061AVA4_CYBFA Cyberlindnera fabianii Flap endonuclease 1
A0A0A8L257 A0A0A8L257_9SACH Kluyveromyces dobzhanskii CBS 2104 Flap endonuclease 1
A0A0C7MZB6 A0A0C7MZB6_9SACH Lachancea lanzarotensis Flap endonuclease 1
A0A0H5C3W9 fen1 Cyberlindnera jadinii NRRL Y-1542 Flap endonuclease 1
A0A0P1KME9 A0A0P1KME9_9SACH Lachancea quebecensis Flap endonuclease 1
A0A0W0CYV4 A0A0W0CYV4_CANGB Nakaseomyces glabratus Flap endonuclease 1
A0A109UW95 A0A109UW95_9SACH Eremothecium sinecaudum Flap endonuclease 1