MTQ2 - Saccharomyces cerevisiae S288C
eRF1 methyltransferase catalytic subunit MTQ2
> MTQ2 - Saccharomyces cerevisiae S288C [eRF1 methyltransferase catalytic subunit MTQ2]
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Metadata
Organism Source: 559292 - Saccharomyces cerevisiae S288C
EC Number: 2.1.1.297
Cluster:
Registry Model:
Reactions
| reaction id | name | note |
|---|---|---|
| KEGG:R10806 | S-adenosyl-L-methionine:[protein]-L-glutamine (N5-glutamine)-methyltransferase | The enzyme ec 2.1.1.297 methylates peptide chain release factor 1 or 2 [KO:K02835 K02836]. |
| BioCyc:RXN-14992 | S-ADENOSYLMETHIONINE + Release-factor-L-glutamine --> Release-factor-N5-Methyl-L-glutamine + ADENOSYL-HOMO-CYS + PROTON | |
| Rhea:RHEA:42897 | L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine => N5-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine + H+ | Release factors are methylated on the Gln residue of a universally conserved tripeptide motif GGQ. |
| Rhea:RHEA:42898 | N5-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine + H+ => L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine | Release factors are methylated on the Gln residue of a universally conserved tripeptide motif GGQ. |
| Rhea:RHEA:42899 | L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine <=> N5-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine + H+ | Release factors are methylated on the Gln residue of a universally conserved tripeptide motif GGQ. |
Pathways
| pathway id | name |
|---|---|
| Reactome:R-SCE-1430728 | Metabolism |
| Reactome:R-SCE-72766 | Translation |
| Reactome:R-SCE-72764 | Eukaryotic Translation Termination |
| Reactome:R-SCE-156580 | Phase II - Conjugation of compounds |
| Reactome:R-SCE-156581 | Methylation |
| Reactome:R-SCE-211859 | Biological oxidations |
| Reactome:R-SCE-392499 | Metabolism of proteins |