GLR1 - Saccharomyces cerevisiae S288C
Glutathione reductase
> GLR1 - Saccharomyces cerevisiae S288C [Glutathione reductase]
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Metadata
Organism Source: 559292 - Saccharomyces cerevisiae S288C
EC Number: 1.8.1.7
Cluster:
Registry Model:
Reactions
| reaction id | name | note |
|---|---|---|
| KEGG:R00094 | glutathione:NAD+ oxidoreductase | NADP+ (see R00115) |
| KEGG:R00115 | glutathione:NADP+ oxidoreductase | 2 Glutathione + NADP+ <=> Glutathione disulfide + NADPH + H+ |
| BioCyc:GLUTATHIONE-REDUCT-NADPH-RXN | OXIDIZED-GLUTATHIONE + NADPH + PROTON --> 2 GLUTATHIONE + NADP | This reaction is necessary to recycle oxidized glutathioneto maintain high levels of reduced glutathione in the cytosol. |
| Rhea:RHEA:11741 | 2 glutathione + NADP+ => glutathione disulfide + NADPH + H+ | |
| Rhea:RHEA:11742 | glutathione disulfide + NADPH + H+ => 2 glutathione + NADP+ | |
| Rhea:RHEA:11743 | 2 glutathione + NADP+ <=> glutathione disulfide + NADPH + H+ |
Pathways
| pathway id | name |
|---|---|
| BioCyc:YEAST_PWY-4081 | glutathione redox reactions I |
| Reactome:R-SCE-9711123 | Cellular response to chemical stress |
| Reactome:R-SCE-3700989 | Transcriptional Regulation by TP53 |
| Reactome:R-SCE-8953897 | Cellular responses to stimuli |
| Reactome:R-SCE-212436 | Generic Transcription Pathway |
| Reactome:R-SCE-3299685 | Detoxification of Reactive Oxygen Species |
| Reactome:R-SCE-1430728 | Metabolism |
| Reactome:R-SCE-5628897 | TP53 Regulates Metabolic Genes |
| Reactome:R-SCE-15869 | Nucleotide metabolism |
| Reactome:R-SCE-499943 | Interconversion of nucleotide di- and triphosphates |
| Reactome:R-SCE-74160 | Gene expression (Transcription) |
| Reactome:R-SCE-73857 | RNA Polymerase II Transcription |
| Reactome:R-SCE-2262752 | Cellular responses to stress |
| PathBank:SMP0002304 | TCA Cycle |
| PathBank:SMP0002355 | Pyruvate Metabolism |