DPH5
K00586 DPH5; diphthine methyl ester synthase [EC:2.1.1.314]
Protein Function: diphthine methyl ester synthase [EC:2.1.1.314]
DBLinks
Proteins
| protein id | name | function | taxonomy source |
|---|
Reactions
| reaction id | name | note |
|---|---|---|
| KEGG:R11165 | S-adenosyl-L-methionine:2-[(3S)-3-carboxy-3-aminopropyl]-L-histidine-[translation elongation factor 2] methyltransferase (diphthine methyl ester-[translation elongation factor 2]-forming) | 4 S-Adenosyl-L-methionine + Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine <=> 4 S-Adenosyl-L-homocysteine + Peptide diphthine methyl ester |
| Rhea:RHEA:42653 | 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine => diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H+ | |
| Rhea:RHEA:42654 | diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H+ => 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine | |
| Rhea:RHEA:42655 | 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine <=> diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H+ | |
| BioCyc:RXN-15775 | 4 S-ADENOSYLMETHIONINE + 2-3-CARBOXY-3-AMINOPROPYL-L-HISTIDINE --> Diphthine-methyl-ester-EF2 + 4 ADENOSYL-HOMO-CYS + 3 PROTON | |
| KEGG:R04481 | S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase | subsequently R08468 |
| KEGG:R08468 | S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase | following after R04481, subsequently R08469 |
| KEGG:R08469 | S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase | following after R08468 |
| KEGG:R10306 | S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine-[translation elongation factor 2] methyltransferase | 3 S-Adenosyl-L-methionine + Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine <=> 3 S-Adenosyl-L-homocysteine + Peptide diphthine |
| Rhea:RHEA:36416 | 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 3 S-adenosyl-L-methionine => diphthine-[translation elongation factor 2] + 3 S-adenosyl-L-homocysteine + 3 H+ | Multi-step reaction: RHEA:36419 and RHEA:36423 and RHEA:36427. |