TRP1
K13501 TRP1; anthranilate synthase / indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:4.1.3.27 4.1.1.48 5.3.1.24]
Protein Function: anthranilate synthase / indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:4.1.3.27 4.1.1.48 5.3.1.24]
DBLinks
Proteins
| protein id | name | function | taxonomy source |
|---|
Reactions
| reaction id | name | note |
|---|---|---|
| KEGG:R03508 | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase(cyclizing) | 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate <=> Indoleglycerol phosphate + CO2 + H2O |
| BioCyc:IGPSYN-RXN | PROTON + CARBOXYPHENYLAMINO-DEOXYRIBULOSE-P --> INDOLE-3-GLYCEROL-P + CARBON-DIOXIDE + WATER | this is the fourth reaction in the tryptophan synthesis pathway |
| Rhea:RHEA:23477 | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ => (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O | |
| Rhea:RHEA:23478 | (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O => 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ | |
| Rhea:RHEA:23479 | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H+ <=> (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O | |
| KEGG:R00985 | chorismate pyruvate-lyase (amino-accepting; anthranilate-forming) | Chorismate + Ammonia <=> Anthranilate + Pyruvate + H2O |
| KEGG:R00986 | chorismate pyruvate-lyase (amino-accepting) | Chorismate + L-Glutamine <=> Anthranilate + Pyruvate + L-Glutamate |
| BioCyc:ANTHRANSYN-RXN | CHORISMATE + GLN --> PROTON + ANTHRANILATE + PYRUVATE + GLT | |
| Rhea:RHEA:21733 | chorismate + L-glutamine => anthranilate + pyruvate + L-glutamate + H+ | Multi-step reaction: RHEA:15889 + RHEA:55676 + RHEA:55680 |
| Rhea:RHEA:21734 | anthranilate + pyruvate + L-glutamate + H+ => chorismate + L-glutamine | Multi-step reaction: RHEA:15889 + RHEA:55676 + RHEA:55680 |