PAICS
K01587 PAICS; phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]
Protein Function: phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]
DBLinks
Proteins
| protein id | name | function | taxonomy source |
|---|
Reactions
| reaction id | name | note |
|---|---|---|
| KEGG:R04209 | 1-(5-phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase | 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate <=> Aminoimidazole ribotide + CO2 |
| BioCyc:AIRCARBOXY-RXN | PHOSPHORIBOSYL-CARBOXY-AMINOIMIDAZOLE + 2 PROTON<=>5-PHOSPHORIBOSYL-5-AMINOIMIDAZOLE + CARBON-DIOXIDE | |
| Rhea:RHEA:10793 | 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H+ => 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + CO2 | |
| Rhea:RHEA:10794 | 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + CO2 => 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H+ | |
| Rhea:RHEA:10795 | 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H+ <=> 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + CO2 | |
| KEGG:R04591 | 1-(5-phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming) | ATP + 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate + L-Aspartate <=> ADP + Orthophosphate + 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole |
| BioCyc:SAICARSYN-RXN | ATP + PHOSPHORIBOSYL-CARBOXY-AMINOIMIDAZOLE + L-ASPARTATE --> PROTON + ADP + Pi + P-RIBOSYL-4-SUCCCARB-AMINOIMIDAZOLE | |
| Rhea:RHEA:22629 | 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP => (2S)-2-[5-amino-1-(5-phospho-β-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + phosphate + 2 H+ | |
| Rhea:RHEA:22630 | (2S)-2-[5-amino-1-(5-phospho-β-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + phosphate + 2 H+ => 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP | |
| Rhea:RHEA:22631 | 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP <=> (2S)-2-[5-amino-1-(5-phospho-β-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + phosphate + 2 H+ |