mepS, spr

K13694 mepS, spr; murein DD-endopeptidase / murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13]

Protein Function: murein DD-endopeptidase / murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13]

DBLinks
Proteins
protein id name function taxonomy source
Reactions
reaction id name note
KEGG:R04313 C03793 + 2 C00017<=>C05546 + 2 C00001 multi-step reaction
KEGG:R04869 C05552 + 2 C00012<=>C06250 + 2 C00001 Biocytin + 2 Peptide <=> Holo-[carboxylase] + 2 H2O
KEGG:R10891 C20917 + C00001<=>C20918 + C00188 putative tabtoxin peptidase
BioCyc:RXN-22576 CPD-24805 + WATER --> A-PEPTIDOGLYCAN-MDAP-TRIPEPTIDE + GLY
BioCyc:RXN0-5407 CPD0-1185 + WATER --> A-PEPTIDOGLYCAN-MDAP-TRIPEPTIDE + CPD-24859 This reaction represents hydrolysis of meso-DAP-meso-DAP (3 → 3) cross-links in peptidoglycan (see |CITS: [23066944]| for nomenclature of endopeptidase activity in E. coli K-12).
BioCyc:RXN-22575 CPD0-1171 + WATER --> a-murein-lipoprotein + A-PEPTIDOGLYCAN-MDAP-TRIPEPTIDE
BioCyc:RXN0-3461 CPD0-2579 + WATER --> CPD-17931 + CPD-17986 This reaction represents DD endopeptidase activity - hydrolysis of the meso-diaminopimelyl-D-alanyl bond in cross-linked peptidoglycan (see |CITS: [23066944]| for nomenclature of endopeptidase activity in E. coli K-12).
BioCyc:RXN-16664 CPD-17926 + WATER --> CPD-17968 + D-ALANINE This reaction may also be catalysed by the L,D-transpeptidases LdtA, LdtB, LdtC and LdtE |CITS: [18456808]|.
BioCyc:RXN0-5227 CPD0-1082 + WATER --> L-ALA-GAMMA-D-GLU-DAP + D-ALANINE
BioCyc:RXN0-2061 UDP-MURNAC-TETRAPEPTIDE + WATER --> D-ALANINE + UDP-AAGM-DIAMINOHEPTANEDIOATE