TPS3

Short Conclusion Abstract: TPS3 (terpene synthase 3) is a multifunctional plant enzyme primarily catalyzing the cyclization and rearrangement of geranyl diphosphate (GPP) to produce key monoterpenes, including (-)-camphene, (4S)-limonene, and myrcene (with EC 4.2.3.117 for (4S)-limonene synthase activity). It does not typically produce tricyclene (which is associated with other TPS enzymes). Biologically, TPS3-derived monoterpenes serve critical roles in plant defense (e.g., deterring herbivores and pathogens) and ecological signaling (e.g., attracting pollinators or mediating plant-plant communication). In Arabidopsis thaliana, TPS3 is induced by stress (e.g., herbivory) and contributes to volatile organic compound (VOC) emission, directly linking its enzymatic activity to adaptive fitness in natural environments.

(Note: EC 4.2.3.105, 4.2.3.16, and 4.2.3.15 refer to other terpene synthases; TPS3 specifically aligns with EC 4.2.3.117 for (4S)-limonene production.)

Protein Function: (-)-camphene/tricyclene/(4S)-limonene/myrcene synthase [EC:4.2.3.117 4.2.3.105 4.2.3.16 4.2.3.15]

DBLinks
Proteins
protein id name function taxonomy source
Reactions
reaction id name note
KEGG:R09961 geranyl-diphosphate diphosphate-lyase (cyclizing; tricyclene-forming) Geranyl diphosphate <=> Tricyclene + Diphosphate
Rhea:RHEA:32688 (2E)-geranyl diphosphate => tricyclene + diphosphate
Rhea:RHEA:32689 tricyclene + diphosphate => (2E)-geranyl diphosphate
Rhea:RHEA:32690 (2E)-geranyl diphosphate <=> tricyclene + diphosphate
BioCyc:RXN-5121 GERANYL-PP --> CPD-4902 + PPI
KEGG:R09972 geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-camphene-forming] Geranyl diphosphate <=> (-)-Camphene + Diphosphate
Rhea:RHEA:25485 (2E)-geranyl diphosphate => (1S,4R)-camphene + diphosphate
Rhea:RHEA:25486 (1S,4R)-camphene + diphosphate => (2E)-geranyl diphosphate
Rhea:RHEA:25487 (2E)-geranyl diphosphate <=> (1S,4R)-camphene + diphosphate
BioCyc:RXN-5142 GERANYL-PP --> CPD-4921 + PPI