Pathways Knowlegdes

Necessitatibus eius consequatur ex aliquid fuga eum quidem sint consectetur velit

Pathway DOIs Note
Metabolism

Accession ID: Reactome:R-BTA-1430728		 -
Metabolism of lipids

Accession ID: Reactome:R-BTA-556833		 -
Bile acid and bile salt metabolism

Accession ID: Reactome:R-BTA-194068
  • 10.1006/bbrc.2001.2013
  • 10.1053/j.gastro.2003.06.005
  • 10.1146/annurev.biochem.72.121801.161712
  • 10.1152/physrev.00027.2002
 Kullak-Ublick GA, Stieger B, Meier PJ. Enterohepatic bile salt transporters in normal physiology and liver disease. Gastroenterology. 2004 Jan;126(1):322–42. doi: 10.1053/j.gastro.2003.06.005. PMID: 14699511.; Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72():137–74. doi: 10.1146/annurev.biochem.72.121801.161712. PMID: 12543708.; Trauner M, Boyer JL. Bile salt transporters: molecular characterization, function, and regulation. Physiol Rev. 2003 Apr;83(2):633–71. doi: 10.1152/physrev.00027.2002. PMID: 12663868.; Javitt NB. Cholesterol, Hydroxycholesterols, and Bile Acids. Biochemical and Biophysical Research Communications. 2002 Apr;292(5):1147–53. doi: 10.1006/bbrc.2001.2013.
Bile acid and bile salt metabolism

Accession ID: Reactome:R-CEL-194068
  • 10.1006/bbrc.2001.2013
  • 10.1053/j.gastro.2003.06.005
  • 10.1146/annurev.biochem.72.121801.161712
  • 10.1152/physrev.00027.2002
 Kullak-Ublick GA, Stieger B, Meier PJ. Enterohepatic bile salt transporters in normal physiology and liver disease. Gastroenterology. 2004 Jan;126(1):322–42. doi: 10.1053/j.gastro.2003.06.005. PMID: 14699511.; Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72():137–74. doi: 10.1146/annurev.biochem.72.121801.161712. PMID: 12543708.; Trauner M, Boyer JL. Bile salt transporters: molecular characterization, function, and regulation. Physiol Rev. 2003 Apr;83(2):633–71. doi: 10.1152/physrev.00027.2002. PMID: 12663868.; Javitt NB. Cholesterol, Hydroxycholesterols, and Bile Acids. Biochemical and Biophysical Research Communications. 2002 Apr;292(5):1147–53. doi: 10.1006/bbrc.2001.2013.
Metabolism

Accession ID: Reactome:R-CFA-1430728		 -
Metabolism of lipids

Accession ID: Reactome:R-CFA-556833		 -
Bile acid and bile salt metabolism

Accession ID: Reactome:R-CFA-194068
  • 10.1006/bbrc.2001.2013
  • 10.1053/j.gastro.2003.06.005
  • 10.1146/annurev.biochem.72.121801.161712
  • 10.1152/physrev.00027.2002
 Kullak-Ublick GA, Stieger B, Meier PJ. Enterohepatic bile salt transporters in normal physiology and liver disease. Gastroenterology. 2004 Jan;126(1):322–42. doi: 10.1053/j.gastro.2003.06.005. PMID: 14699511.; Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72():137–74. doi: 10.1146/annurev.biochem.72.121801.161712. PMID: 12543708.; Trauner M, Boyer JL. Bile salt transporters: molecular characterization, function, and regulation. Physiol Rev. 2003 Apr;83(2):633–71. doi: 10.1152/physrev.00027.2002. PMID: 12663868.; Javitt NB. Cholesterol, Hydroxycholesterols, and Bile Acids. Biochemical and Biophysical Research Communications. 2002 Apr;292(5):1147–53. doi: 10.1006/bbrc.2001.2013.
Bile acid and bile salt metabolism

Accession ID: Reactome:R-DME-194068
  • 10.1006/bbrc.2001.2013
  • 10.1053/j.gastro.2003.06.005
  • 10.1146/annurev.biochem.72.121801.161712
  • 10.1152/physrev.00027.2002
 Kullak-Ublick GA, Stieger B, Meier PJ. Enterohepatic bile salt transporters in normal physiology and liver disease. Gastroenterology. 2004 Jan;126(1):322–42. doi: 10.1053/j.gastro.2003.06.005. PMID: 14699511.; Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72():137–74. doi: 10.1146/annurev.biochem.72.121801.161712. PMID: 12543708.; Trauner M, Boyer JL. Bile salt transporters: molecular characterization, function, and regulation. Physiol Rev. 2003 Apr;83(2):633–71. doi: 10.1152/physrev.00027.2002. PMID: 12663868.; Javitt NB. Cholesterol, Hydroxycholesterols, and Bile Acids. Biochemical and Biophysical Research Communications. 2002 Apr;292(5):1147–53. doi: 10.1006/bbrc.2001.2013.
Bile acid and bile salt metabolism

Accession ID: Reactome:R-GGA-194068
  • 10.1006/bbrc.2001.2013
  • 10.1053/j.gastro.2003.06.005
  • 10.1146/annurev.biochem.72.121801.161712
  • 10.1152/physrev.00027.2002
 Kullak-Ublick GA, Stieger B, Meier PJ. Enterohepatic bile salt transporters in normal physiology and liver disease. Gastroenterology. 2004 Jan;126(1):322–42. doi: 10.1053/j.gastro.2003.06.005. PMID: 14699511.; Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72():137–74. doi: 10.1146/annurev.biochem.72.121801.161712. PMID: 12543708.; Trauner M, Boyer JL. Bile salt transporters: molecular characterization, function, and regulation. Physiol Rev. 2003 Apr;83(2):633–71. doi: 10.1152/physrev.00027.2002. PMID: 12663868.; Javitt NB. Cholesterol, Hydroxycholesterols, and Bile Acids. Biochemical and Biophysical Research Communications. 2002 Apr;292(5):1147–53. doi: 10.1006/bbrc.2001.2013.
Bile acid and bile salt metabolism

Accession ID: Reactome:R-HSA-194068
  • 10.1006/bbrc.2001.2013
  • 10.1053/j.gastro.2003.06.005
  • 10.1146/annurev.biochem.72.121801.161712
  • 10.1152/physrev.00027.2002
 Kullak-Ublick GA, Stieger B, Meier PJ. Enterohepatic bile salt transporters in normal physiology and liver disease. Gastroenterology. 2004 Jan;126(1):322–42. doi: 10.1053/j.gastro.2003.06.005. PMID: 14699511.; Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72():137–74. doi: 10.1146/annurev.biochem.72.121801.161712. PMID: 12543708.; Trauner M, Boyer JL. Bile salt transporters: molecular characterization, function, and regulation. Physiol Rev. 2003 Apr;83(2):633–71. doi: 10.1152/physrev.00027.2002. PMID: 12663868.; Javitt NB. Cholesterol, Hydroxycholesterols, and Bile Acids. Biochemical and Biophysical Research Communications. 2002 Apr;292(5):1147–53. doi: 10.1006/bbrc.2001.2013.
Metabolism

Accession ID: Reactome:R-MMU-1430728		 -
Metabolism of lipids

Accession ID: Reactome:R-MMU-556833		 -
Metabolism of steroids

Accession ID: Reactome:R-MMU-8957322
  • 10.1007/bf00054556
  • 10.1146/annurev.biochem.72.121801.161712
  • 10.1152/ajprenal.00336.2004
  • 10.1194/jlr.r800054-jlr200
  • 10.1210/er.2003-0030
 Brown MS, Goldstein JL. Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL. Journal of Lipid Research. 2009 Apr;50():S15–27. doi: 10.1194/jlr.r800054-jlr200.; Dusso AS, Brown AJ, Slatopolsky E. Vitamin D. American Journal of Physiology-Renal Physiology. 2005 Jul;289(1):F8–F28. doi: 10.1152/ajprenal.00336.2004.; Payne AH, Hales DB. Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones. Endocr Rev. 2004 Dec;25(6):947–70. doi: 10.1210/er.2003-0030. PMID: 15583024.; Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72():137–74. doi: 10.1146/annurev.biochem.72.121801.161712. PMID: 12543708.; Russell DW. Cholesterol biosynthesis and metabolism. Cardiovasc Drugs Ther. 1992 Apr;6(2):103–10. doi: 10.1007/bf00054556. PMID: 1390320.
Synthesis of bile acids and bile salts via 24-hydroxycholesterol

Accession ID: Reactome:R-MMU-193775
  • 10.1006/bbrc.2001.2013
  • 10.1016/s0022-2275(20)32188-x
  • 10.1146/annurev.biochem.72.121801.161712
 Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72():137–74. doi: 10.1146/annurev.biochem.72.121801.161712. PMID: 12543708.; Javitt NB. Cholesterol, Hydroxycholesterols, and Bile Acids. Biochemical and Biophysical Research Communications. 2002 Apr;292(5):1147–53. doi: 10.1006/bbrc.2001.2013.; Björkhem I, Lütjohann D, Diczfalusy U, Ståhle L, Ahlborg G, Wahren J. Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation. Journal of Lipid Research. 1998 Aug;39(8):1594–600. doi: 10.1016/s0022-2275(20)32188-x.
Bile acid and bile salt metabolism

Accession ID: Reactome:R-XTR-194068
  • 10.1006/bbrc.2001.2013
  • 10.1053/j.gastro.2003.06.005
  • 10.1146/annurev.biochem.72.121801.161712
  • 10.1152/physrev.00027.2002
 Kullak-Ublick GA, Stieger B, Meier PJ. Enterohepatic bile salt transporters in normal physiology and liver disease. Gastroenterology. 2004 Jan;126(1):322–42. doi: 10.1053/j.gastro.2003.06.005. PMID: 14699511.; Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72():137–74. doi: 10.1146/annurev.biochem.72.121801.161712. PMID: 12543708.; Trauner M, Boyer JL. Bile salt transporters: molecular characterization, function, and regulation. Physiol Rev. 2003 Apr;83(2):633–71. doi: 10.1152/physrev.00027.2002. PMID: 12663868.; Javitt NB. Cholesterol, Hydroxycholesterols, and Bile Acids. Biochemical and Biophysical Research Communications. 2002 Apr;292(5):1147–53. doi: 10.1006/bbrc.2001.2013.
Metabolism of steroids

Accession ID: Reactome:R-BTA-8957322
  • 10.1007/bf00054556
  • 10.1146/annurev.biochem.72.121801.161712
  • 10.1152/ajprenal.00336.2004
  • 10.1194/jlr.r800054-jlr200
  • 10.1210/er.2003-0030
 Brown MS, Goldstein JL. Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL. Journal of Lipid Research. 2009 Apr;50():S15–27. doi: 10.1194/jlr.r800054-jlr200.; Dusso AS, Brown AJ, Slatopolsky E. Vitamin D. American Journal of Physiology-Renal Physiology. 2005 Jul;289(1):F8–F28. doi: 10.1152/ajprenal.00336.2004.; Payne AH, Hales DB. Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones. Endocr Rev. 2004 Dec;25(6):947–70. doi: 10.1210/er.2003-0030. PMID: 15583024.; Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72():137–74. doi: 10.1146/annurev.biochem.72.121801.161712. PMID: 12543708.; Russell DW. Cholesterol biosynthesis and metabolism. Cardiovasc Drugs Ther. 1992 Apr;6(2):103–10. doi: 10.1007/bf00054556. PMID: 1390320.
Synthesis of bile acids and bile salts via 24-hydroxycholesterol

Accession ID: Reactome:R-BTA-193775
  • 10.1006/bbrc.2001.2013
  • 10.1016/s0022-2275(20)32188-x
  • 10.1146/annurev.biochem.72.121801.161712
 Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72():137–74. doi: 10.1146/annurev.biochem.72.121801.161712. PMID: 12543708.; Javitt NB. Cholesterol, Hydroxycholesterols, and Bile Acids. Biochemical and Biophysical Research Communications. 2002 Apr;292(5):1147–53. doi: 10.1006/bbrc.2001.2013.; Björkhem I, Lütjohann D, Diczfalusy U, Ståhle L, Ahlborg G, Wahren J. Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation. Journal of Lipid Research. 1998 Aug;39(8):1594–600. doi: 10.1016/s0022-2275(20)32188-x.
Metabolism of lipids

Accession ID: Reactome:R-CEL-556833		 -
Metabolism of steroids

Accession ID: Reactome:R-CEL-8957322
  • 10.1007/bf00054556
  • 10.1146/annurev.biochem.72.121801.161712
  • 10.1152/ajprenal.00336.2004
  • 10.1194/jlr.r800054-jlr200
  • 10.1210/er.2003-0030
 Brown MS, Goldstein JL. Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL. Journal of Lipid Research. 2009 Apr;50():S15–27. doi: 10.1194/jlr.r800054-jlr200.; Dusso AS, Brown AJ, Slatopolsky E. Vitamin D. American Journal of Physiology-Renal Physiology. 2005 Jul;289(1):F8–F28. doi: 10.1152/ajprenal.00336.2004.; Payne AH, Hales DB. Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones. Endocr Rev. 2004 Dec;25(6):947–70. doi: 10.1210/er.2003-0030. PMID: 15583024.; Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72():137–74. doi: 10.1146/annurev.biochem.72.121801.161712. PMID: 12543708.; Russell DW. Cholesterol biosynthesis and metabolism. Cardiovasc Drugs Ther. 1992 Apr;6(2):103–10. doi: 10.1007/bf00054556. PMID: 1390320.
Synthesis of bile acids and bile salts via 24-hydroxycholesterol

Accession ID: Reactome:R-CEL-193775
  • 10.1006/bbrc.2001.2013
  • 10.1016/s0022-2275(20)32188-x
  • 10.1146/annurev.biochem.72.121801.161712
 Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72():137–74. doi: 10.1146/annurev.biochem.72.121801.161712. PMID: 12543708.; Javitt NB. Cholesterol, Hydroxycholesterols, and Bile Acids. Biochemical and Biophysical Research Communications. 2002 Apr;292(5):1147–53. doi: 10.1006/bbrc.2001.2013.; Björkhem I, Lütjohann D, Diczfalusy U, Ståhle L, Ahlborg G, Wahren J. Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation. Journal of Lipid Research. 1998 Aug;39(8):1594–600. doi: 10.1016/s0022-2275(20)32188-x.