Pathways Knowlegdes

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Pathway DOIs Note
superpathway of central carbon metabolism

Accession ID: BioCyc:LEISH_PWY3IU-99
  • 10.1073/pnas.0603539103
Sernee MF, Ralton JE, Dinev Z, Khairallah GN, O’Hair RA, Williams SJ, McConville MJ. Leishmania ß-1,2-mannan is assembled on a mannose-cyclic phosphate primer. Proc. Natl. Acad. Sci. U.S.A. 2006 Jun 20;103(25):9458–63. doi: 10.1073/pnas.0603539103.
TCA cycle

Accession ID: BioCyc:LEISH_TCA
  • 10.1016/j.molbiopara.2006.04.010
  • 10.2307/3285729
Leroux A, Fleming-Canepa X, Aranda A, Maugeri D, Cazzulo JJ, Sánchez MA, Nowicki C. Functional characterization and subcellular localization of the three malate dehydrogenase isozymes in Leishmania spp. Molecular and Biochemical Parasitology. 2006 Sep;149(1):74–85. doi: 10.1016/j.molbiopara.2006.04.010.; Louassini M, Foulquie M, Benitez R, Adroher J. Citric-Acid Cycle Key Enzyme Activities during In vitro Growth and Metacyclogenesis of Leishmania infantum Promastigotes. The Journal of Parasitology. 1999 Aug;85(4):595. doi: 10.2307/3285729.
methylmalonyl pathway

Accession ID: BioCyc:LEISH_PROPIONMET-PWY
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superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass

Accession ID: BioCyc:TRYPANO_GLYCOLYSIS-TCA-GLYOX-BYPASS
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aspartate superpathway

Accession ID: BioCyc:TRYPANO_PWY0-781
-
superpathway of glycolysis, pyruvate dehydrogenase and TCA cycle

Accession ID: BioCyc:LEISH_PWY3IU-61
-
TCA cycle

Accession ID: BioCyc:TRYPANO_TCA
-
superpathway of lysine, threonine and methionine biosynthesis I

Accession ID: BioCyc:TRYPANO_P4-PWY
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phenylacetate degradation I (aerobic)

Accession ID: BioCyc:TRYPANO_PWY0-321
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lysine biosynthesis I

Accession ID: BioCyc:TRYPANO_DAPLYSINESYN-PWY
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acetyl-CoA degradation to acetate

Accession ID: BioCyc:LEISH_PWY3IU-16
  • 10.1016/j.pt.2007.02.004
  • 10.1073/pnas.95.6.3036
Opperdoes FR, Coombs GH. Metabolism of Leishmania: proven and predicted. Trends Parasitol. 2007 Apr;23(4):149–58. doi: 10.1016/j.pt.2007.02.004. PMID: 17320480.; Van Hellemond JJ, Opperdoes FR, Tielens AGM. Trypanosomatidae produce acetate via a mitochondrial acetate:succinate CoA transferase. Proc. Natl. Acad. Sci. U.S.A. 1998 Mar 17;95(6):3036–41. doi: 10.1073/pnas.95.6.3036.
3-oxoadipate degradation

Accession ID: BioCyc:TRYPANO_PWY-2361
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benzoyl-CoA degradation I (aerobic)

Accession ID: BioCyc:TRYPANO_PWY-1361
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pyruvate fermentation to propionate I

Accession ID: BioCyc:TRYPANO_P108-PWY
-
superpathway of glyoxylate bypass and TCA

Accession ID: BioCyc:TRYPANO_TCA-GLYOX-BYPASS
-
methionine biosynthesis I

Accession ID: BioCyc:TRYPANO_HOMOSER-METSYN-PWY
-
Central carbon metabolism

Accession ID: WikiPathways:WP3583
  • 10.1038/msb.2011.9
2011; 7 477
TCA cycle (plant)

Accession ID: Plant Reactome:R-OGU-1119533
  • 10.1016/0003-9861(81)90297-6
  • 10.1016/j.tplants.2010.05.006
  • 10.1042/bj20100497
  • 10.1074/jbc.m109.097477
  • 10.1104/pp.59.4.630
  • 10.1111/j.1365-3040.2011.02332.x
  • 10.1146/annurev-arplant-042110-103857
Araújo WL, Nunes-Nesi A, Nikoloski Z, Sweetlove LJ, Fernie AR. Metabolic control and regulation of the tricarboxylic acid cycle in photosynthetic and heterotrophic plant tissues. Plant Cell Environ. 2012 Jan;35(1):1–21. doi: 10.1111/j.1365-3040.2011.02332.x. PMID: 21477125.; Millar AH, Whelan J, Soole KL, Day DA. Organization and regulation of mitochondrial respiration in plants. Annu Rev Plant Biol. 2011;62():79–104. doi: 10.1146/annurev-arplant-042110-103857. PMID: 21332361.; Tronconi MA, Gerrard Wheeler MC, Maurino VG, Drincovich MF, Andreo CS. NAD-malic enzymes of Arabidopsis thaliana display distinct kinetic mechanisms that support differences in physiological control. Biochem J. 2010 Sep 01;430(2):295–303. doi: 10.1042/bj20100497. PMID: 20528775.; Sweetlove LJ, Beard KF, Nunes-Nesi A, Fernie AR, Ratcliffe RG. Not just a circle: flux modes in the plant TCA cycle. Trends Plant Sci. 2010 Aug;15(8):462–70. doi: 10.1016/j.tplants.2010.05.006. PMID: 20554469.; Tronconi MA, Maurino VG, Andreo CS, Drincovich MF. Three Different and Tissue-specific NAD-Malic Enzymes Generated by Alternative Subunit Association in Arabidopsis thaliana. Journal of Biological Chemistry. 2010 Apr;285(16):11870–9. doi: 10.1074/jbc.m109.097477.; Grover SD, Canellas PF, Wedding RT. Purification of NAD malic enzyme from potato and investigation of some physical and kinetic properties. Archives of Biochemistry and Biophysics. 1981 Jul;209(2):396–407. doi: 10.1016/0003-9861(81)90297-6.; Day DA, Hanson JB. Pyruvate and malate transport and oxidation in corn mitochondria. Plant Physiol. 1977 Apr;59(4):630–5. PMID: 16659908; PMCID: PMC542463.
TCA cycle (plant)

Accession ID: Plant Reactome:R-CCA-1119533
  • 10.1016/0003-9861(81)90297-6
  • 10.1016/j.tplants.2010.05.006
  • 10.1042/bj20100497
  • 10.1074/jbc.m109.097477
  • 10.1104/pp.59.4.630
  • 10.1111/j.1365-3040.2011.02332.x
  • 10.1146/annurev-arplant-042110-103857
Araújo WL, Nunes-Nesi A, Nikoloski Z, Sweetlove LJ, Fernie AR. Metabolic control and regulation of the tricarboxylic acid cycle in photosynthetic and heterotrophic plant tissues. Plant Cell Environ. 2012 Jan;35(1):1–21. doi: 10.1111/j.1365-3040.2011.02332.x. PMID: 21477125.; Millar AH, Whelan J, Soole KL, Day DA. Organization and regulation of mitochondrial respiration in plants. Annu Rev Plant Biol. 2011;62():79–104. doi: 10.1146/annurev-arplant-042110-103857. PMID: 21332361.; Tronconi MA, Gerrard Wheeler MC, Maurino VG, Drincovich MF, Andreo CS. NAD-malic enzymes of Arabidopsis thaliana display distinct kinetic mechanisms that support differences in physiological control. Biochem J. 2010 Sep 01;430(2):295–303. doi: 10.1042/bj20100497. PMID: 20528775.; Sweetlove LJ, Beard KF, Nunes-Nesi A, Fernie AR, Ratcliffe RG. Not just a circle: flux modes in the plant TCA cycle. Trends Plant Sci. 2010 Aug;15(8):462–70. doi: 10.1016/j.tplants.2010.05.006. PMID: 20554469.; Tronconi MA, Maurino VG, Andreo CS, Drincovich MF. Three Different and Tissue-specific NAD-Malic Enzymes Generated by Alternative Subunit Association in Arabidopsis thaliana. Journal of Biological Chemistry. 2010 Apr;285(16):11870–9. doi: 10.1074/jbc.m109.097477.; Grover SD, Canellas PF, Wedding RT. Purification of NAD malic enzyme from potato and investigation of some physical and kinetic properties. Archives of Biochemistry and Biophysics. 1981 Jul;209(2):396–407. doi: 10.1016/0003-9861(81)90297-6.; Day DA, Hanson JB. Pyruvate and malate transport and oxidation in corn mitochondria. Plant Physiol. 1977 Apr;59(4):630–5. PMID: 16659908; PMCID: PMC542463.
TCA cycle (plant)

Accession ID: Plant Reactome:R-JCU-1119533
  • 10.1016/0003-9861(81)90297-6
  • 10.1016/j.tplants.2010.05.006
  • 10.1042/bj20100497
  • 10.1074/jbc.m109.097477
  • 10.1104/pp.59.4.630
  • 10.1111/j.1365-3040.2011.02332.x
  • 10.1146/annurev-arplant-042110-103857
Araújo WL, Nunes-Nesi A, Nikoloski Z, Sweetlove LJ, Fernie AR. Metabolic control and regulation of the tricarboxylic acid cycle in photosynthetic and heterotrophic plant tissues. Plant Cell Environ. 2012 Jan;35(1):1–21. doi: 10.1111/j.1365-3040.2011.02332.x. PMID: 21477125.; Millar AH, Whelan J, Soole KL, Day DA. Organization and regulation of mitochondrial respiration in plants. Annu Rev Plant Biol. 2011;62():79–104. doi: 10.1146/annurev-arplant-042110-103857. PMID: 21332361.; Tronconi MA, Gerrard Wheeler MC, Maurino VG, Drincovich MF, Andreo CS. NAD-malic enzymes of Arabidopsis thaliana display distinct kinetic mechanisms that support differences in physiological control. Biochem J. 2010 Sep 01;430(2):295–303. doi: 10.1042/bj20100497. PMID: 20528775.; Sweetlove LJ, Beard KF, Nunes-Nesi A, Fernie AR, Ratcliffe RG. Not just a circle: flux modes in the plant TCA cycle. Trends Plant Sci. 2010 Aug;15(8):462–70. doi: 10.1016/j.tplants.2010.05.006. PMID: 20554469.; Tronconi MA, Maurino VG, Andreo CS, Drincovich MF. Three Different and Tissue-specific NAD-Malic Enzymes Generated by Alternative Subunit Association in Arabidopsis thaliana. Journal of Biological Chemistry. 2010 Apr;285(16):11870–9. doi: 10.1074/jbc.m109.097477.; Grover SD, Canellas PF, Wedding RT. Purification of NAD malic enzyme from potato and investigation of some physical and kinetic properties. Archives of Biochemistry and Biophysics. 1981 Jul;209(2):396–407. doi: 10.1016/0003-9861(81)90297-6.; Day DA, Hanson JB. Pyruvate and malate transport and oxidation in corn mitochondria. Plant Physiol. 1977 Apr;59(4):630–5. PMID: 16659908; PMCID: PMC542463.