Pathways Knowlegdes

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Pathway DOIs Note
sesamin biosynthesis

Accession ID: BioCyc:META_PWY-5469
  • 10.1021/jf0258961
  • 10.1073/pnas.0603865103
  • 10.1093/ajcn/72.3.804
  • 10.1093/jn/132.5.961
  • 10.1248/bpb.26.1701
  • 10.3177/jnsv.49.270
 Ono E, Nakai M, Fukui Y, Tomimori N, Fukuchi-Mizutani M, Saito M, Satake H, Tanaka T, Katsuta M, Umezawa T, Tanaka Y. Formation of two methylenedioxy bridges by a Sesamum CYP81Q protein yielding a furofuran lignan, (+)-sesamin. Proc. Natl. Acad. Sci. U.S.A. 2006 Jun 27;103(26):10116–21. doi: 10.1073/pnas.0603865103.; Nakano D, Itoh C, Ishii F, Kawanishi H, Takaoka M, Kiso Y, Tsuruoka N, Tanaka T, Matsumura Y. Effects of Sesamin on Aortic Oxidative Stress and Endothelial Dysfunction in Deoxycorticosterone Acetate-Salt Hypertensive Rats. Biological & Pharmaceutical Bulletin. 2003;26(12):1701–5. doi: 10.1248/bpb.26.1701.; IKEDA S, KAGAYA M, KOBAYASHI K, TOHYAMA T, KISO Y, HIGUCHI N, YAMASHITA K. Dietary Sesame Lignans Decrease Lipid Peroxidation in Rats Fed Docosahexaenoic Acid. Journal of Nutritional Science and Vitaminology, J Nutr Sci Vitaminol. 2003;49(4):270–6. doi: 10.3177/jnsv.49.270.; Nakai M, Harada M, Nakahara K, Akimoto K, Shibata H, Miki W, Kiso Y. Novel antioxidative metabolites in rat liver with ingested sesamin. J Agric Food Chem. 2003 Mar 12;51(6):1666–70. doi: 10.1021/jf0258961. PMID: 12617602.; Ikeda S, Tohyama T, Yamashita K. Dietary sesame seed and its lignans inhibit 2,7,8-trimethyl- 2(2'-carboxyethyl)-6-hydroxychroman excretion into urine of rats fed gamma-tocopherol. J Nutr. 2002 May;132(5):961–6. doi: 10.1093/jn/132.5.961. PMID: 11983822.; Utsunomiya T, Chavali SR, Zhong WW, Forse RA. Effects of sesamin-supplemented dietary fat emulsions on the ex vivo production of lipopolysaccharide-induced prostanoids and tumor necrosis factor a in rats. The American Journal of Clinical Nutrition. 2000 Sep;72(3):804–8. doi: 10.1093/ajcn/72.3.804.
sesaminol glucoside biosynthesis

Accession ID: BioCyc:META_PWY-7139
  • 10.1016/j.neures.2006.06.005
  • 10.1021/jf051541g
  • 10.1021/jf901215j
  • 10.1093/jn/136.4.906
  • 10.1093/pcp/pcp088
  • 10.1111/j.1365-313x.2008.03428.x
  • 10.1248/bpb.32.1516
 Um MY, Ahn JY, Kim S, Kim MK, Ha TY. Sesaminol Glucosides Protect .BETA.-Amyloid Peptide-Induced Cognitive Deficits in Mice. Biological & Pharmaceutical Bulletin. 2009;32(9):1516–20. doi: 10.1248/bpb.32.1516.; Masada S, Terasaka K, Oguchi Y, Okazaki S, Mizushima T, Mizukami H. Functional and structural characterization of a flavonoid glucoside 1,6-glucosyltransferase from Catharanthus roseus. Plant Cell Physiol. 2009 Aug;50(8):1401–15. doi: 10.1093/pcp/pcp088. PMID: 19561332.; Jan KC, Hwang LS, Ho CT. Biotransformation of sesaminol triglucoside to mammalian lignans by intestinal microbiota. J Agric Food Chem. 2009 Jul 22;57(14):6101–6. doi: 10.1021/jf901215j. PMID: 19537732.; Noguchi A, Fukui Y, Iuchi-Okada A, Kakutani S, Satake H, Iwashita T, Nakao M, Umezawa T, Ono E. Sequential glucosylation of a furofuran lignan, (+)-sesaminol, by Sesamum indicum UGT71A9 and UGT94D1 glucosyltransferases. The Plant Journal. 2008 Jan 31;54(3):415–27. doi: 10.1111/j.1365-313x.2008.03428.x.; Lee SY, Son DJ, Lee YK, Lee JW, Lee HJ, Yun YW, Ha TY, Hong JT. Inhibitory effect of sesaminol glucosides on lipopolysaccharide-induced NF-kappaB activation and target gene expression in cultured rat astrocytes. Neurosci Res. 2006 Oct;56(2):204–12. doi: 10.1016/j.neures.2006.06.005. PMID: 16842873.; Liu Z, Saarinen NM, Thompson LU. Sesamin Is One of the Major Precursors of Mammalian Lignans in Sesame Seed (Sesamum indicum) as Observed In Vitro and in Rats , The Journal of Nutrition. 2006 Apr;136(4):906–12. doi: 10.1093/jn/136.4.906.; Moazzami AA, Andersson RE, Kamal-Eldin A. HPLC analysis of sesaminol glucosides in sesame seeds. J Agric Food Chem. 2006 Feb 08;54(3):633–8. doi: 10.1021/jf051541g. PMID: 16448160.
sesaminol glucoside biosynthesis

Accession ID: PlantCyc:SPENNELLII_PWY-7139		 -
sesamin biosynthesis

Accession ID: PlantCyc:ALYRATA_PWY-5469		 -
sesamin biosynthesis

Accession ID: PlantCyc:SWITCHGRASS_PWY-5469		 -
sesamin biosynthesis

Accession ID: PlantCyc:TPARVULA_PWY-5469		 -
sesamin biosynthesis

Accession ID: PlantCyc:ASPARAGUS_PWY-5469		 -
sesamin biosynthesis

Accession ID: PlantCyc:BARLEY_PWY-5469		 -
sesamin biosynthesis

Accession ID: PlantCyc:BRACHYPODIUM_PWY-5469		 -
sesamin biosynthesis

Accession ID: PlantCyc:BRAPA_FPSC_PWY-5469		 -
sesamin biosynthesis

Accession ID: PlantCyc:BSTRICTA_PWY-5469		 -
sesamin biosynthesis

Accession ID: PlantCyc:CARIETINUM_ICC4958_PWY-5469		 -
sesaminol glucoside biosynthesis

Accession ID: PlantCyc:CGIGANTEA_PWY-7139		 -
sesamin biosynthesis

Accession ID: PlantCyc:DROTUNDATA_PWY-5469		 -
sesamin biosynthesis

Accession ID: PlantCyc:HOP_PWY-5469		 -
sesamin biosynthesis

Accession ID: PlantCyc:KFEDTSCHENKOI_PWY-5469		 -
sesamin biosynthesis

Accession ID: PlantCyc:LPERRIERI_PWY-5469		 -
sesamin biosynthesis

Accession ID: PlantCyc:NTABACUM_TN90_PWY-5469		 -
sesaminol glucoside biosynthesis

Accession ID: PlantCyc:OEUROPAEA_SYLVESTRIS_PWY-7139		 -
sesamin biosynthesis

Accession ID: PlantCyc:OILSEEDRAPE_PWY-5469		 -