Pathways Knowlegdes

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Pathway DOIs Note
superpathway of leucine, valine, and isoleucine biosynthesis

Accession ID: BioCyc:CALBI_BRANCHED-CHAIN-AA-SYN-PWY
  • 10.1128/mmbr.67.1.1-15.2003
 Kohlhaw GB. Leucine biosynthesis in fungi: entering metabolism through the back door. Microbiol Mol Biol Rev. 2003 Mar;67(1):1–15, table of contents. PMID: 12626680; PMCID: PMC150519.
cysteine degradation

Accession ID: BioCyc:CALBI_CYSTEINE-DEG-PWY
  • 10.1038/213396a0
 Falcone G, Giambanco V. Synthesis of seleno-amino-acids in cell free extracts of Candida albicans. Nature. 1967 Jan 28;213(5074):396–8. doi: 10.1038/213396a0. PMID: 6029526.
alanine biosynthesis

Accession ID: BioCyc:CALBI_ALANINE-SYN2-PWY
  • 10.1016/0378-1097(91)90285-i
  • 10.1016/j.ijmm.2007.03.020
  • 10.1271/bbb.58.283
 Kusch H, Engelmann S, Bode R, Albrecht D, Morschhäuser J, Hecker M. A proteomic view of Candida albicans yeast cell metabolism in exponential and stationary growth phases. International Journal of Medical Microbiology. 2008 Apr;298(3-4):291–318. doi: 10.1016/j.ijmm.2007.03.020.; Biallasiewicz D, Kwasniewska J. [The capability of deamination of aminoacids by selected strains of fungi]. Wiad Parazytol. 2001;47(3):339–44. PMID: 16894744.; Umemura I, Yanagiya K, Komatsubara S, Sato T, Tosa T. Purification and Some Properties of Alanine Aminotransferase fromCandida maltosa. Bioscience, Biotechnology, and Biochemistry. 1994 Jan;58(2):283–7. doi: 10.1271/bbb.58.283.; Kaur S, Mishra P. Amino acid uptake as a function of differentiation in Candida albicans: studies of a non-germinative variant. FEMS Microbiol Lett. 1991 Aug 15;66(3):341–4. doi: 10.1016/0378-1097(91)90285-i. PMID: 1769529.; Verma RS, Prasad R. Absence of derepression of amino acids transport in Candida. Biochem Int. 1983 Dec;7(6):707–17. PMID: 6385985.
valine biosynthesis

Accession ID: BioCyc:CALBI_VALSYN-PWY
  • 10.1007/bf00387766
  • 10.1128/ec.5.5.816-824.2006
  • 10.1128/jb.151.3.1247-1252.1982
 Kingsbury JM, Goldstein AL, McCusker JH. Role of Nitrogen and Carbon Transport, Regulation, and Metabolism Genes for Saccharomyces cerevisiae Survival In Vivo. Eukaryot Cell. 2006 May;5(5):816–24. doi: 10.1128/ec.5.5.816-824.2006.; Holmberg S, Petersen JG. Regulation of isoleucine-valine biosynthesis in Saccharomyces cerevisiae. Curr Genet. 1988 Mar;13(3):207–17. doi: 10.1007/bf00387766. PMID: 3289762.; Kakar SN, Magee PT. Genetic analysis of Candida albicans: identification of different isoleucine-valine, methionine, and arginine alleles by complementation. J Bacteriol. 1982 Sep;151(3):1247–52. doi: 10.1128/jb.151.3.1247-1252.1982.; Szentirmai A, Horváth I. Regulation of branched-chain amino acid biosynthesis. Acta Microbiol Acad Sci Hung. 1976;23(2):137–49. PMID: 788468.
glycolysis

Accession ID: BioCyc:CALBI_GLYCOLYSIS
  • 10.1007/bf00442632
  • 10.1016/j.bbrc.2006.07.066
  • 10.1016/s0378-1097(00)00311-6
  • 10.1080/02681219480000611
  • 10.1086/432104
  • 10.1128/mmbr.62.2.334-361.1998
 Watanabe T, Ogasawara A, Mikami T, Matsumoto T. Hyphal formation of Candida albicans is controlled by electron transfer system. Biochemical and Biophysical Research Communications. 2006 Sep;348(1):206–11. doi: 10.1016/j.bbrc.2006.07.066.; Andes D, Lepak A, Pitula A, Marchillo K, Clark J. A simple approach for estimating gene expression in Candida albicans directly from a systemic infection site. J Infect Dis. 2005 Sep 01;192(5):893–900. doi: 10.1086/432104. PMID: 16088840.; Saeed FA. Production of pyruvate by Candida albicans: proposed role in virulence. FEMS Microbiol Lett. 2000 Sep 01;190(1):35–8. doi: 10.1111/j.1574-6968.2000.tb09258.x. PMID: 10981686.; Gancedo JM. Yeast Carbon Catabolite Repression. Microbiol Mol Biol Rev. 1998 Jun;62(2):334–61. doi: 10.1128/mmbr.62.2.334-361.1998.; Cho T, Hagihara Y, Kaminishi H, Watanabe K. The relationship between the glucose uptake system and growth cessation in Candida albicans. J Med Vet Mycol. 1994 Dec;32(6):461–6. doi: 10.1080/02681219480000611. PMID: 7738728.; Schwartz DS, Larsh HW. Comparative activities of glycolytic enzymes in yeast and mycelial forms of Candida albicans. Mycopathologia. 1982 May 22;78(2):93–8. doi: 10.1007/bf00442632. PMID: 6212766.
N-acetylglucosamine , N-acetylmannosamine and N-acetylneuraminic acid dissimilation

Accession ID: BioCyc:CALBI_GLCMANNANAUT-PWY
  • 10.1073/pnas.250452997
  • 10.1128/iai.69.12.7898-7903.2001
 Singh P, Ghosh S, Datta A. Attenuation of Virulence and Changes in Morphology in Candida albicans by Disruption of the N -Acetylglucosamine Catabolic Pathway. Infect Immun. 2001 Dec;69(12):7898–903. doi: 10.1128/iai.69.12.7898-7903.2001.; Kumar MJ, Jamaluddin MS, Natarajan K, Kaur D, Datta A. The inducible N -acetylglucosamine catabolic pathway gene cluster in Candida albicans : Discrete N -acetylglucosamine-inducible factors interact at the promoter of NAG1. Proc. Natl. Acad. Sci. U.S.A. 2000 Dec 12;97(26):14218–23. doi: 10.1073/pnas.250452997.
Central carbon metabolism

Accession ID: WikiPathways:WP3583
  • 10.1038/msb.2011.9
 2011; 7 477
2,3-Dihydroxybenzoate Biosynthesis

Accession ID: PathBank:SMP0000774		 -
Biosynthesis of Siderophore Group Nonribosomal Peptides

Accession ID: PathBank:SMP0000783		 -
D-Alanine Metabolism

Accession ID: PathBank:SMP0000791		 -
Lysine Biosynthesis

Accession ID: PathBank:SMP0000794		 -
Glycolysis and Pyruvate Dehydrogenase

Accession ID: PathBank:SMP0000807		 -
L-Alanine Metabolism

Accession ID: PathBank:SMP0000810		 -
D-Glucarate and D-Galactarate Degradation

Accession ID: PathBank:SMP0000816		 -
Serine Biosynthesis and Metabolism

Accession ID: PathBank:SMP0000829		 -
Valine Biosynthesis

Accession ID: PathBank:SMP0000832		 -
Tryptophan Metabolism

Accession ID: PathBank:SMP0000835		 -
Isoleucine Biosynthesis

Accession ID: PathBank:SMP0000838		 -
Gluconeogenesis from L-Malic Acid

Accession ID: PathBank:SMP0000839		 -
Galactitol and Galactonate Degradation

Accession ID: PathBank:SMP0000840		 -