Pathways Knowlegdes

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Pathway DOIs Note
TCA cycle, aerobic respiration

Accession ID: BioCyc:CALBI_PWY3B3-100
  • 10.1016/s0021-9258(19)50315-5
  • 10.1074/jbc.272.50.31382
  • 10.1074/jbc.m304091200
  • 10.1128/jb.84.4.778-783.1962
 Yasutake Y, Watanabe S, Yao M, Takada Y, Fukunaga N, Tanaka I. Crystal Structure of the Monomeric Isocitrate Dehydrogenase in the Presence of NADP+. Journal of Biological Chemistry. 2003 Sep;278(38):36897–904. doi: 10.1074/jbc.m304091200.; Oyedotun KS, Lemire BD. The Carboxyl Terminus of the Saccharomyces cerevisiaeSuccinate Dehydrogenase Membrane Subunit, SDH4p, Is Necessary for Ubiquinone Reduction and Enzyme Stability. Journal of Biological Chemistry. 1997 Dec;272(50):31382–8. doi: 10.1074/jbc.272.50.31382.; Haselbeck RJ, McAlister-Henn L. Function and expression of yeast mitochondrial NAD- and NADP-specific isocitrate dehydrogenases. Journal of Biological Chemistry. 1993 Jun;268(16):12116–22. doi: 10.1016/s0021-9258(19)50315-5.; RAO GR, SIRSI M, RAMAKRISHNAN T. Enzymes in Candida albicans. II. Tricarboxylic acid cycle and related enzymes. J Bacteriol. 1962 Oct;84():778–83. PMID: 13973046; PMCID: PMC277958.
gluconeogenesis

Accession ID: BioCyc:CALBI_GLUCONEO-PWY
  • 10.1099/00221287-144-1-13
 Klein CJL, Olsson L, Nielsen J. Glucose control in Saccharomyces cerevisiae: the role of Mig1 in metabolic functions. Microbiology (Reading). 1998 Jan;144 ( Pt 1)():13–24. doi: 10.1099/00221287-144-1-13. PMID: 9467897.
asparagine degradation

Accession ID: BioCyc:CALBI_ASPARAGINE-DEG1-PWY
  • 10.1271/bbb.59.749
 Kil J, Kim G, Park I. Extraction of ExtracellularL-Asparaginase fromCandida utilis. Bioscience, Biotechnology, and Biochemistry. 1995 Jan;59(4):749–50. doi: 10.1271/bbb.59.749.
aspartate biosynthesis

Accession ID: BioCyc:CALBI_ASPBIO-PWY		 -
aspartate degradation

Accession ID: BioCyc:CALBI_MALATE-ASPARTATE-SHUTTLE-PWY		 -
glutamine degradation

Accession ID: BioCyc:CALBI_GLUTAMINEFUM-PWY
  • 10.1016/s0168-6445(99)00030-3
  • 10.1099/00221287-133-1-9
 ter Schure EG, van Riel NA, Verrips CT. The role of ammonia metabolism in nitrogen catabolite repression in Saccharomyces cerevisiae. FEMS Microbiol Rev. 2000 Jan;24(1):67–83. doi: 10.1111/j.1574-6976.2000.tb00533.x. PMID: 10640599.; Soberón M, González A. Glutamine degradation through the omega-amidase pathway in Saccharomyces cerevisiae. J Gen Microbiol. 1987 Jan;133(1):9–14. doi: 10.1099/00221287-133-1-9. PMID: 3309146.
glyoxylate cycle

Accession ID: BioCyc:CALBI_GLYOXYLATE-BYPASS
  • 10.1038/35083594
  • 10.1046/j.1365-2958.2003.03396.x
  • 10.1046/j.1365-2958.2003.03412.x
  • 10.1111/j.1439-0507.2006.01192.x
  • 10.1111/j.1462-5822.2005.00676.x
  • 10.1128/ec.00372-06
  • 10.1128/ec.1.5.657-662.2002
  • 10.1247/csf.21.117
 Ramírez MA, Lorenz MC. Mutations in alternative carbon utilization pathways in Candida albicans attenuate virulence and confer pleiotropic phenotypes. Eukaryot Cell. 2007 Feb;6(2):280–90. PMID: 17158734; PMCID: PMC1797957.; Barelle CJ, Priest CL, MacCallum DM, Gow NAR, Odds FC, Brown AJP. Niche-specific regulation of central metabolic pathways in a fungal pathogen. Cell Microbiol. 2006 Jun;8(6):961–71. doi: 10.1111/j.1462-5822.2005.00676.x.; Lattif AA, Prasad R, Banerjee U, Gupta N, Mohammad S, Baquer NZ. The glyoxylate cycle enzyme activities in the pathogenic isolates of Candida albicans obtained from HIV/AIDS, diabetic and burn patients. Mycoses. 2006 Mar;49(2):85–90. doi: 10.1111/j.1439-0507.2006.01192.x. PMID: 16466439.; Fradin C, Kretschmar M, Nichterlein T, Gaillardin C, D’Enfert C, Hube B. Stage-specific gene expression of Candida albicans in human blood. Molecular Microbiology. 2003 Mar;47(6):1523–43. doi: 10.1046/j.1365-2958.2003.03396.x.; Wang ZY, Thornton CR, Kershaw MJ, Debao L, Talbot NJ. The glyoxylate cycle is required for temporal regulation of virulence by the plant pathogenic fungus Magnaporthe grisea. Mol Microbiol. 2003 Mar;47(6):1601–12. doi: 10.1046/j.1365-2958.2003.03412.x. PMID: 12622815.; Lorenz MC, Fink GR. Life and Death in a Macrophage: Role of the Glyoxylate Cycle in Virulence. Eukaryot Cell. 2002 Oct;1(5):657–62. doi: 10.1128/ec.1.5.657-662.2002.; Lorenz MC, Fink GR. The glyoxylate cycle is required for fungal virulence. Nature. 2001 Jul 05;412(6842):83–6. doi: 10.1038/35083594. PMID: 11452311.; Kamasawa N, Ohtsuka I, Kamada Y, Ueda M, Tanaka A, Osumi M. Immunoelectron microscopic observation of the behaviors of peroxisomal enzymes inducibly synthesized in an n-alkane-utilizable yeast cell, Candida tropicalis. Cell Struct Funct. 1996 Apr;21(2):117–22. doi: 10.1247/csf.21.117. PMID: 8790941.
asparagine biosynthesis

Accession ID: BioCyc:CALBI_ASPARAGINE-BIOSYNTHESIS
  • 10.1046/j.1365-2958.1996.d01-1715.x
 Dang V, Valens M, Bolotin-Fukuhara M, Daignan-Fornier B. Cloning of the ASN1 and ASN2 genes encoding asparagine synthetases in Saccharomyces cerevisiae: differential regulation by the CCAAT-box-binding factor. Molecular Microbiology. 1996 Nov;22(4):681–92. doi: 10.1046/j.1365-2958.1996.d01-1715.x.
Central carbon metabolism

Accession ID: WikiPathways:WP3583
  • 10.1038/msb.2011.9
 2011; 7 477
TCA Cycle

Accession ID: PathBank:SMP0000802		 -
Aspartate Metabolism

Accession ID: PathBank:SMP0000809		 -
L-Glutamate Metabolism

Accession ID: PathBank:SMP0000811		 -
Asparagine Biosynthesis

Accession ID: PathBank:SMP0000833		 -
Threonine Biosynthesis

Accession ID: PathBank:SMP0000837		 -
Gluconeogenesis from L-Malic Acid

Accession ID: PathBank:SMP0000839		 -
Propanoate Metabolism

Accession ID: PathBank:SMP0000957		 -
Secondary Metabolites: Glyoxylate Cycle

Accession ID: PathBank:SMP0000983		 -
TCA cycle (ubiquinol-2)

Accession ID: PathBank:SMP0001018		 -
TCA cycle (ubiquinol-3)

Accession ID: PathBank:SMP0001019		 -
TCA cycle (ubiquinol-4)

Accession ID: PathBank:SMP0001020		 -