Pathways Knowlegdes

Necessitatibus eius consequatur ex aliquid fuga eum quidem sint consectetur velit

Pathway DOIs Note
pyridine nucleotide cycling (plants)

Accession ID: BioCyc:LEISH_PWY-5381		 -
aldoxime degradation

Accession ID: BioCyc:TRYPANO_P345-PWY		 -
pyridine nucleotide cycling

Accession ID: BioCyc:TRYPANO_PYRNUCYC-PWY		 -
NAD salvage pathway I

Accession ID: WikiPathways:WP2486
  • 10.1002/prot.340200407
 Bork P, Koonin EV. A P-loop-like motif in a widespread ATP pyrophosphatase domain: implications for the evolution of sequence motifs and enzyme activity. Proteins. 1994 Dec;20(4):347–55. doi: 10.1002/prot.340200407. PMID: 7731953.
NAD Salvage

Accession ID: PathBank:SMP0000850		 -
Adenosylcobalamin Salvage from Cobinamide

Accession ID: PathBank:SMP0001898		 -
trigonelline biosynthesis

Accession ID: PlantCyc:SOY_PWY-5110
  • 10.1002/(sici)1521-3773(20000417)39:8<1400::aid-anie1400>3.0.co;2-z
  • 10.1007/s004250000272
  • 10.1016/0003-9861(88)90396-7
  • 10.1016/0006-291x(83)91763-1
  • 10.1016/s0021-9258(18)50141-1
  • 10.1016/s0021-9258(18)64575-2
  • 10.1093/jxb/eri156
 Zheng XQ, Hayashibe E, Ashihara H. Changes in trigonelline (N-methylnicotinic acid) content and nicotinic acid metabolism during germination of mungbean (Phaseolus aureus) seeds. J Exp Bot. 2005 Jun;56(416):1615–23. doi: 10.1093/jxb/eri156. PMID: 15837705.; Mazzuca S, Bitonti MB, Innocenti AM, Francis D. Inactivation of DNA replication origins by the cell cycle regulator, trigonelline, in root meristems of Lactuca sativa. Planta. 2000 Jun;211(1):127–32. doi: 10.1007/s004250000272. PMID: 10923713.; Ueda, Yamamura. Chemistry and Biology of Plant Leaf Movements. Angew Chem Int Ed Engl. 2000 Apr;39(8):1400–14. doi: 10.1002/(sici)1521-3773(20000417)39:8<1400::aid-anie1400>3.0.co;2-z. PMID: 10777626.; Upmeier B, Gross W, Ko¨ster S, Barz W. Purification and properties of S-adenosyl-l-methionine:Nicotinic acid-N-methyltransferase from cell suspension cultures of Glycine max L. Archives of Biochemistry and Biophysics. 1988 May;262(2):445–54. doi: 10.1016/0003-9861(88)90396-7.; Taguchi H, Shimabayashi Y. Findings of trigonelline demethylating enzyme activity in various organisms and some properties of the enzyme from hog liver. Biochemical and Biophysical Research Communications. 1983 Jun;113(2):569–74. doi: 10.1016/0006-291x(83)91763-1.; Heeger V, Leienbach KW, Barz W. [Metabolism of nicotinic acid in plant cell suspension cultures, III: Formation and metabolism of trigonelline (author's transl)]. Hoppe Seylers Z Physiol Chem. 1976 Aug;357(8):1081–7. PMID: 185134.; Joshi JG, Handler P. Metabolism of Trigonelline. Journal of Biological Chemistry. 1962 Oct;237(10):3185–8. doi: 10.1016/s0021-9258(18)50141-1.; Joshi JG, Handler P. Biosynthesis of Trigonelline. Journal of Biological Chemistry. 1960 Oct;235(10):2981–3. doi: 10.1016/s0021-9258(18)64575-2.
pyridine nucleotide cycling (plants)

Accession ID: PlantCyc:ARA_PWY-5381
  • 10.1016/s0006-291x(82)80105-8
  • 10.1016/s0021-9258(18)64575-2
  • 10.1023/a:1026590521318
  • 10.1038/212933a0
  • 10.1093/jxb/eri156
  • 10.1093/jxb/erj202
  • 10.1104/pp.53.4.603
 Noctor G, Queval G, Gakière B. NAD(P) synthesis and pyridine nucleotide cycling in plants and their potential importance in stress conditions. J Exp Bot. 2006;57(8):1603–20. doi: 10.1093/jxb/erj202. PMID: 16714307.; Zheng XQ, Hayashibe E, Ashihara H. Changes in trigonelline (N-methylnicotinic acid) content and nicotinic acid metabolism during germination of mungbean (Phaseolus aureus) seeds. J Exp Bot. 2005 Jun;56(416):1615–23. doi: 10.1093/jxb/eri156. PMID: 15837705.; Sinclair SJ, Murphy KJ, Birch CD, Hamill JD. Molecular characterization of quinolinate phosphoribosyltransferase (QPRtase) in Nicotiana. Plant Mol Biol. 2000 Nov;44(5):603–17. doi: 10.1023/a:1026590521318. PMID: 11198422.; Eastwell KC, Stumpf PK. The presence of 5'-nucleotidase in Swiss chard chloroplasts. Biochemical and Biophysical Research Communications. 1982 Oct;108(4):1690–4. doi: 10.1016/s0006-291x(82)80105-8.; Mann DF, Byerrum RU. Activation of the de Novo Pathway for Pyridine Nucleotide Biosynthesis Prior to Ricinine Biosynthesis in Castor Beans. Plant Physiol. 1974 Apr 01;53(4):603–9. doi: 10.1104/pp.53.4.603.; Gholson RK. The pyridine nucleotide cycle. Nature. 1966 Nov 26;212(5065):933–5. doi: 10.1038/212933a0. PMID: 4306794.; Joshi JG, Handler P. Biosynthesis of Trigonelline. Journal of Biological Chemistry. 1960 Oct;235(10):2981–3. doi: 10.1016/s0021-9258(18)64575-2.
nicotine biosynthesis

Accession ID: PlantCyc:NTABACUM_TN90_PWY-5316
  • 10.1007/s11103-004-3352-7
  • 10.1073/pnas.0506581102
 Siminszky B, Gavilano L, Bowen SW, Dewey RE. Conversion of nicotine to nornicotine in Nicotiana tabacum is mediated by CYP82E4, a cytochrome P450 monooxygenase. Proc. Natl. Acad. Sci. U.S.A. 2005 Sep 28;102(41):14919–24. doi: 10.1073/pnas.0506581102.; Heim WG, Jelesko JG. Association of diamine oxidase and S-adenosylhomocysteine hydrolase in Nicotiana tabacum extracts. Plant Mol Biol. 2004 Sep;56(2):299–308. doi: 10.1007/s11103-004-3352-7. PMID: 15604745.
NAD salvage (plants)

Accession ID: PlantCyc:NTABACUM_TN90_PWY-5381		 -
trigonelline biosynthesis

Accession ID: PlantCyc:PLANT_PWY-5110
  • 10.1002/(sici)1521-3773(20000417)39:8<1400::aid-anie1400>3.0.co;2-z
  • 10.1007/s004250000272
  • 10.1016/0003-9861(88)90396-7
  • 10.1016/0006-291x(83)91763-1
  • 10.1016/s0021-9258(18)64575-2
  • 10.1093/jxb/eri156
 Zheng XQ, Hayashibe E, Ashihara H. Changes in trigonelline (N-methylnicotinic acid) content and nicotinic acid metabolism during germination of mungbean (Phaseolus aureus) seeds. J Exp Bot. 2005 Jun;56(416):1615–23. doi: 10.1093/jxb/eri156. PMID: 15837705.; Mazzuca S, Bitonti MB, Innocenti AM, Francis D. Inactivation of DNA replication origins by the cell cycle regulator, trigonelline, in root meristems of Lactuca sativa. Planta. 2000 Jun;211(1):127–32. doi: 10.1007/s004250000272. PMID: 10923713.; Ueda, Yamamura. Chemistry and Biology of Plant Leaf Movements. Angew Chem Int Ed Engl. 2000 Apr;39(8):1400–14. doi: 10.1002/(sici)1521-3773(20000417)39:8<1400::aid-anie1400>3.0.co;2-z. PMID: 10777626.; Upmeier B, Gross W, Ko¨ster S, Barz W. Purification and properties of S-adenosyl-l-methionine:Nicotinic acid-N-methyltransferase from cell suspension cultures of Glycine max L. Archives of Biochemistry and Biophysics. 1988 May;262(2):445–54. doi: 10.1016/0003-9861(88)90396-7.; Taguchi H, Shimabayashi Y. Findings of trigonelline demethylating enzyme activity in various organisms and some properties of the enzyme from hog liver. Biochemical and Biophysical Research Communications. 1983 Jun;113(2):569–74. doi: 10.1016/0006-291x(83)91763-1.; Heeger V, Leienbach KW, Barz W. [Metabolism of nicotinic acid in plant cell suspension cultures, III: Formation and metabolism of trigonelline (author's transl)]. Hoppe Seylers Z Physiol Chem. 1976 Aug;357(8):1081–7. PMID: 185134.; Joshi JG, Handler P. Biosynthesis of Trigonelline. Journal of Biological Chemistry. 1960 Oct;235(10):2981–3. doi: 10.1016/s0021-9258(18)64575-2.
N-glucosylnicotinate metabolism

Accession ID: PlantCyc:PLANT_PWY-5388
  • 10.1016/0003-9861(75)90485-3
 Sutter A, Grisebach H. Free reversibility of the UDP-glucose: Flavonol 3-O-glucosyltransferase reaction. Archives of Biochemistry and Biophysics. 1975 Apr;167(2):444–7. doi: 10.1016/0003-9861(75)90485-3.
pyridine nucleotide cycling (plants)

Accession ID: PlantCyc:PLANT_PWY-5381
  • 10.1016/s0006-291x(82)80105-8
  • 10.1016/s0021-9258(18)64575-2
  • 10.1023/a:1026590521318
  • 10.1038/212933a0
  • 10.1093/jxb/eri156
  • 10.1093/jxb/erj202
  • 10.1104/pp.53.4.603
 Noctor G, Queval G, Gakière B. NAD(P) synthesis and pyridine nucleotide cycling in plants and their potential importance in stress conditions. J Exp Bot. 2006;57(8):1603–20. doi: 10.1093/jxb/erj202. PMID: 16714307.; Zheng XQ, Hayashibe E, Ashihara H. Changes in trigonelline (N-methylnicotinic acid) content and nicotinic acid metabolism during germination of mungbean (Phaseolus aureus) seeds. J Exp Bot. 2005 Jun;56(416):1615–23. doi: 10.1093/jxb/eri156. PMID: 15837705.; Sinclair SJ, Murphy KJ, Birch CD, Hamill JD. Molecular characterization of quinolinate phosphoribosyltransferase (QPRtase) in Nicotiana. Plant Mol Biol. 2000 Nov;44(5):603–17. doi: 10.1023/a:1026590521318. PMID: 11198422.; Eastwell KC, Stumpf PK. The presence of 5'-nucleotidase in Swiss chard chloroplasts. Biochemical and Biophysical Research Communications. 1982 Oct;108(4):1690–4. doi: 10.1016/s0006-291x(82)80105-8.; Mann DF, Byerrum RU. Activation of the de Novo Pathway for Pyridine Nucleotide Biosynthesis Prior to Ricinine Biosynthesis in Castor Beans. Plant Physiol. 1974 Apr 01;53(4):603–9. doi: 10.1104/pp.53.4.603.; Gholson RK. The pyridine nucleotide cycle. Nature. 1966 Nov 26;212(5065):933–5. doi: 10.1038/212933a0. PMID: 4306794.; Joshi JG, Handler P. Biosynthesis of Trigonelline. Journal of Biological Chemistry. 1960 Oct;235(10):2981–3. doi: 10.1016/s0021-9258(18)64575-2.
trigonelline biosynthesis

Accession ID: PlantCyc:AHALLERI_PWY-5110		 -
NAD salvage (plants)

Accession ID: PlantCyc:BANANA_PWY-5381		 -
NAD salvage (plants)

Accession ID: PlantCyc:BRACHYPODIUM_PWY-5381		 -
trigonelline biosynthesis

Accession ID: PlantCyc:CAMELINA_PWY-5110		 -
trigonelline biosynthesis

Accession ID: PlantCyc:CANNUUM_PWY-5110		 -
NAD salvage (plants)

Accession ID: PlantCyc:CASHEW_PWY-5381		 -
trigonelline biosynthesis

Accession ID: PlantCyc:CASHEW_PWY-5110		 -