Pathways Knowlegdes

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Pathway DOIs Note
Eicosanoid metabolism via lipooxygenases (LOX)

Accession ID: WikiPathways:WP4721
  • 10.1038/nri3859
 Dennis EA, Norris PC. Eicosanoid storm in infection and inflammation. Nature Reviews Immunology. 2015 Jul 03;15(8):511–23. doi: 10.1038/nri3859.
Prostaglandin and leukotriene metabolism in senescence

Accession ID: WikiPathways:WP5122
  • 10.3389/fcell.2020.593283
 Lin Y, Xu Z. Fibroblast Senescence in Idiopathic Pulmonary Fibrosis. Front Cell Dev Biol. 2020;8():593283. PMID: 33324646; PMCID: PMC7723977.
Folic acid network

Accession ID: WikiPathways:WP1311
  • 10.1016/j.febslet.2006.08.065
 Lu C, Qiu F, Zhou H, Peng Y, Hao W, Xu J, Yuan J, Wang S, Qiang B, Xu C, Peng X. Identification and characterization of selenoprotein K: an antioxidant in cardiomyocytes. FEBS Lett. 2006 Oct 02;580(22):5189–97. doi: 10.1016/j.febslet.2006.08.065. PMID: 16962588.
Selenium micronutrient network

Accession ID: WikiPathways:WP1272		 - Guzik TJ, Korbut R, Adamek-Guzik T. Nitric oxide and superoxide in inflammation and immune regulation. J Physiol Pharmacol. 2003 Dec;54(4):469–87. PMID: 14726604.
Eicosanoid synthesis

Accession ID: WikiPathways:WP318
  • 10.1126/science.294.5548.1871
 Funk CD. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science. 2001 Nov 30;294(5548):1871–5. doi: 10.1126/science.294.5548.1871. PMID: 11729303.
Prostaglandin and leukotriene metabolism in senescence

Accession ID: WikiPathways:WP5321
  • 10.2174/138161210790883822
 Menna C, Olivieri F, Catalano A, Procopio A. Lipoxygenase inhibitors for cancer prevention: promises and risks. Curr Pharm Des. 2010;16(6):725–33. doi: 10.2174/138161210790883822. PMID: 20388082.
Selenium micronutrient network

Accession ID: WikiPathways:WP15
  • 10.1515/bchm2.1968.349.1.664
 STOFFEL W, LEKIM D, STICHT G. Metabolism of Sphingosine Bases, V. Biosynthesis of Dihydrosphingosinein vitro. Hoppe-Seyler´s Zeitschrift für physiologische Chemie. 1968 Jan;349(1):664–70. doi: 10.1515/bchm2.1968.349.1.664.
Leukotriene metabolic pathway

Accession ID: WikiPathways:WP5171
  • 10.1016/s0022-3565(24)37958-3
 Wheelan P, Hankin JA, Bilir B, Guenette D, Murphy RC. Metabolic Transformations of Leukotriene B4 in Primary Cultures of Human Hepatocytes. The Journal of Pharmacology and Experimental Therapeutics. 1999 Jan;288(1):326–34. doi: 10.1016/s0022-3565(24)37958-3.
Selenium micronutrient network

Accession ID: WikiPathways:WP1310		 - Guzik TJ, Korbut R, Adamek-Guzik T. Nitric oxide and superoxide in inflammation and immune regulation. J Physiol Pharmacol. 2003 Dec;54(4):469–87. PMID: 14726604.
Eicosanoid synthesis

Accession ID: WikiPathways:WP854
  • 10.1126/science.294.5548.1871
 Funk CD. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science. 2001 Nov 30;294(5548):1871–5. doi: 10.1126/science.294.5548.1871. PMID: 11729303.
Eicosanoid synthesis

Accession ID: WikiPathways:WP1090
  • 10.1126/science.294.5548.1871
 Funk CD. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science. 2001 Nov 30;294(5548):1871–5. doi: 10.1126/science.294.5548.1871. PMID: 11729303.
Eicosanoid synthesis

Accession ID: WikiPathways:WP1318
  • 10.1126/science.294.5548.1871
 Funk CD. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science. 2001 Nov 30;294(5548):1871–5. doi: 10.1126/science.294.5548.1871. PMID: 11729303.
Metabolism of alpha-linolenic acid

Accession ID: WikiPathways:WP4586		 -
Arachidonic acid (AA, ARA) oxylipin metabolism

Accession ID: WikiPathways:WP5155
  • 10.1021/cr2002992
 Smith WL, Urade Y, Jakobsson PJ. Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis. Chem Rev. 2011 Oct 12;111(10):5821–65. PMID: 21942677; PMCID: PMC3285496.
Eicosanoid synthesis

Accession ID: WikiPathways:WP293
  • 10.1126/science.294.5548.1871
 Funk CD. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science. 2001 Nov 30;294(5548):1871–5. doi: 10.1126/science.294.5548.1871. PMID: 11729303.
Folic acid network

Accession ID: WikiPathways:WP1273		 -
Eicosanoid metabolism via lipoxygenases (LOX)

Accession ID: WikiPathways:WP4348
  • 10.1038/nri3859
 Dennis EA, Norris PC. Eicosanoid storm in infection and inflammation. Nature Reviews Immunology. 2015 Jul 03;15(8):511–23. doi: 10.1038/nri3859.
Selenium micronutrient network

Accession ID: WikiPathways:WP3257
  • 10.1016/s0022-2275(20)42349-1
 Holleran W, Williams M, Gao W, Elias P. Serine-palmitoyl transferase activity in cultured human keratinocytes. Journal of Lipid Research. 1990 Sep;31(9):1655–61. doi: 10.1016/s0022-2275(20)42349-1.
Eicosanoid synthesis

Accession ID: WikiPathways:WP972
  • 10.1126/science.294.5548.1871
 Funk CD. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science. 2001 Nov 30;294(5548):1871–5. doi: 10.1126/science.294.5548.1871. PMID: 11729303.
Eicosanoid synthesis

Accession ID: WikiPathways:WP167
  • 10.1126/science.294.5548.1871
 Funk CD. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science. 2001 Nov 30;294(5548):1871–5. doi: 10.1126/science.294.5548.1871. PMID: 11729303.