Pathways Knowlegdes

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Pathway DOIs Note
superpathway of central carbon metabolism

Accession ID: BioCyc:LEISH_PWY3IU-99
  • 10.1073/pnas.0603539103
 Sernee MF, Ralton JE, Dinev Z, Khairallah GN, O’Hair RA, Williams SJ, McConville MJ. Leishmania ß-1,2-mannan is assembled on a mannose-cyclic phosphate primer. Proc. Natl. Acad. Sci. U.S.A. 2006 Jun 20;103(25):9458–63. doi: 10.1073/pnas.0603539103.
glycolysis I

Accession ID: BioCyc:LEISH_GLYCOLYSIS
  • 10.1016/j.bbamcr.2006.08.019
 Michels PAM, Bringaud F, Herman M, Hannaert V. Metabolic functions of glycosomes in trypanosomatids. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2006 Dec;1763(12):1463–77. doi: 10.1016/j.bbamcr.2006.08.019.
gluconeogenesis I

Accession ID: BioCyc:LEISH_GLUCONEO-PWY
  • 10.1073/pnas.0509196103
  • 10.1074/jbc.m603265200
 Rodríguez-Contreras D, Landfear SM. Metabolic Changes in Glucose Transporter-deficient Leishmania mexicana and Parasite Virulence. Journal of Biological Chemistry. 2006 Jul;281(29):20068–76. doi: 10.1074/jbc.m603265200.; Naderer T, Ellis MA, Sernee MF, De Souza DP, Curtis J, Handman E, McConville MJ. Virulence of Leishmania major in macrophages and mice requires the gluconeogenic enzyme fructose-1,6-bisphosphatase. Proc. Natl. Acad. Sci. U.S.A. 2006 Apr 04;103(14):5502–7. doi: 10.1073/pnas.0509196103.
galactitol degradation

Accession ID: BioCyc:LEISH_GALACTITOLCAT-PWY		 -
lactose and galactose degradation I

Accession ID: BioCyc:LEISH_LACTOSECAT-PWY		 -
formaldehyde assimilation II (RuMP Cycle)

Accession ID: BioCyc:TRYPANO_PWY-1861		 -
sucrose degradation to ethanol and lactate (anaerobic)

Accession ID: BioCyc:TRYPANO_PWY-3801		 -
pentose phosphate pathway (partial)

Accession ID: BioCyc:TRYPANO_P21-PWY		 -
superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass

Accession ID: BioCyc:TRYPANO_GLYCOLYSIS-TCA-GLYOX-BYPASS		 -
glyoxalase pathway

Accession ID: BioCyc:LEISH_PWY3IU-139
  • 10.1073/pnas.0402918101
  • 10.1073/pnas.84.20.7129
  • 10.1111/j.1742-4658.2005.04632.x
 Sousa Silva M, Ferreira AEN, Tomás AM, Cordeiro C, Ponces Freire A. Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation. The FEBS Journal. 2005 Apr 22;272(10):2388–98. doi: 10.1111/j.1742-4658.2005.04632.x.; Vickers TJ, Greig N, Fairlamb AH. A trypanothione-dependent glyoxalase I with a prokaryotic ancestry in Leishmania major. Proc. Natl. Acad. Sci. U.S.A. 2004 Aug 25;101(36):13186–91. doi: 10.1073/pnas.0402918101.; Darling TN, Davis DG, London RE, Blum JJ. Products of Leishmania braziliensis glucose catabolism: release of D-lactate and, under anaerobic conditions, glycerol. Proc. Natl. Acad. Sci. U.S.A. 1987 Oct;84(20):7129–33. doi: 10.1073/pnas.84.20.7129.
superpathway of glycolysis, pyruvate dehydrogenase and TCA cycle

Accession ID: BioCyc:LEISH_PWY3IU-61		 -
superpathway of glycolysis and Entner-Doudoroff

Accession ID: BioCyc:TRYPANO_GLYCOLYSIS-E-D		 -
pentose phosphate pathway (non-oxidative branch)

Accession ID: BioCyc:TRYPANO_NONOXIPENT-PWY		 -
glycolysis II

Accession ID: BioCyc:TRYPANO_PWY-5484		 -
heterolactic fermentation

Accession ID: BioCyc:TRYPANO_P122-PWY		 -
gluconeogenesis I

Accession ID: BioCyc:TRYPANO_GLUCONEO-PWY		 -
pentose phosphate pathway (non-oxidative branch)

Accession ID: BioCyc:LEISH_NONOXIPENT-PWY
  • 10.1016/s0166-6851(03)00173-7
 Maugeri DA, Cazzulo JJ, Burchmore RJS, Barrett MP, Ogbunude POJ. Pentose phosphate metabolism in Leishmania mexicana. Molecular and Biochemical Parasitology. 2003 Aug;130(2):117–25. doi: 10.1016/s0166-6851(03)00173-7.
Bifidobacterium shunt

Accession ID: BioCyc:TRYPANO_P124-PWY		 -
Entner-Doudoroff pathway III (semi-phosphorylative)

Accession ID: BioCyc:TRYPANO_PWY-2221		 -
glycolysis I

Accession ID: BioCyc:TRYPANO_GLYCOLYSIS		 -