Pathways Knowlegdes

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Pathway DOIs Note
Eicosanoid metabolism via cytochrome P450 monooxygenases pathway

Accession ID: WikiPathways:WP4720
  • 10.1074/jbc.m110.182915
 Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, Myers DS, Glass CK, Hardiman G, Reichart D, Merrill AH, Sullards MC, Wang E, Murphy RC, Raetz CRH, Garrett TA, Guan Z, Ryan AC, Russell DW, McDonald JG, Thompson BM, Shaw WA, Sud M, Zhao Y, Gupta S, Maurya MR, Fahy E, Subramaniam S. A Mouse Macrophage Lipidome. Journal of Biological Chemistry. 2010 Dec;285(51):39976–85. doi: 10.1074/jbc.m110.182915.
Arachidonate epoxygenase / epoxide hydrolase

Accession ID: WikiPathways:WP1250
  • 10.1016/0006-291x(85)90297-9
 Oliw EH, Benthin G. On the metabolism of epoxyeicosatrienoic acids by ram seminal vesicles: Isolation of 5(6)epoxy-prostaglandin F1a. Biochemical and Biophysical Research Communications. 1985 Feb;126(3):1090–6. doi: 10.1016/0006-291x(85)90297-9.
Arachidonate epoxygenase / epoxide hydrolase

Accession ID: WikiPathways:WP678
  • 10.1016/0006-291x(85)90297-9
 Oliw EH, Benthin G. On the metabolism of epoxyeicosatrienoic acids by ram seminal vesicles: Isolation of 5(6)epoxy-prostaglandin F1a. Biochemical and Biophysical Research Communications. 1985 Feb;126(3):1090–6. doi: 10.1016/0006-291x(85)90297-9.
Arachidonic acid (AA, ARA) oxylipin metabolism

Accession ID: WikiPathways:WP5155
  • 10.1021/cr2002992
 Smith WL, Urade Y, Jakobsson PJ. Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis. Chem Rev. 2011 Oct 12;111(10):5821–65. PMID: 21942677; PMCID: PMC3285496.
Arachidonate epoxygenase / epoxide hydrolase

Accession ID: WikiPathways:WP1285
  • 10.1161/01.res.0000187474.47805.30
 Vriens J, Owsianik G, Fisslthaler B, Suzuki M, Janssens A, Voets T, Morisseau C, Hammock BD, Fleming I, Busse R, Nilius B. Modulation of the Ca 2 Permeable Cation Channel TRPV4 by Cytochrome P450 Epoxygenases in Vascular Endothelium. Circulation Research. 2005 Oct 28;97(9):908–15. doi: 10.1161/01.res.0000187474.47805.30.
Eicosanoid metabolism via cytochrome P450 monooxygenases

Accession ID: WikiPathways:WP4349
  • 10.1038/nri3859
 Dennis EA, Norris PC. Eicosanoid storm in infection and inflammation. Nature Reviews Immunology. 2015 Jul 03;15(8):511–23. doi: 10.1038/nri3859.
Arachidonate epoxygenase / epoxide hydrolase

Accession ID: WikiPathways:WP1000
  • 10.1016/s1098-8823(03)00077-7
 Sacerdoti D, Gatta A, McGiff JC. Role of cytochrome P450-dependent arachidonic acid metabolites in liver physiology and pathophysiology. Prostaglandins Other Lipid Mediat. 2003 Oct;72(1-2):51–71. doi: 10.1016/s1098-8823(03)00077-7. PMID: 14626496.
Leukotriene C4 Synthesis Deficiency

Accession ID: PathBank:SMP0120730		 -
Acetylsalicylic Acid Action Pathway

Accession ID: PathBank:SMP0000083		 -
Rofecoxib Action Pathway

Accession ID: PathBank:SMP0000087		 -
Sulindac Action Pathway

Accession ID: PathBank:SMP0000094		 -
Indomethacin Action Pathway

Accession ID: PathBank:SMP0000104		 -
Naproxen Action Pathway

Accession ID: PathBank:SMP0000120		 -
Meloxicam Action Pathway

Accession ID: PathBank:SMP0000106		 -
Antrafenine Action Pathway

Accession ID: PathBank:SMP0000693		 -
Flurbiprofen Action Pathway

Accession ID: PathBank:SMP0000697		 -
Phenylbutazone Action Pathway

Accession ID: PathBank:SMP0000701		 -
Tiaprofenic Acid Action Pathway

Accession ID: PathBank:SMP0000705		 -
Salicylic Acid Action Pathway

Accession ID: PathBank:SMP0000709		 -
Arachidonic Acid Metabolism

Accession ID: PathBank:SMP0000075		 -