Pathways Knowlegdes

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Pathway DOIs Note
Omega-3 / omega-6 fatty acid synthesis

Accession ID: WikiPathways:WP4350
  • 10.1074/jbc.m110.182915
 Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, Myers DS, Glass CK, Hardiman G, Reichart D, Merrill AH, Sullards MC, Wang E, Murphy RC, Raetz CRH, Garrett TA, Guan Z, Ryan AC, Russell DW, McDonald JG, Thompson BM, Shaw WA, Sud M, Zhao Y, Gupta S, Maurya MR, Fahy E, Subramaniam S. A Mouse Macrophage Lipidome. Journal of Biological Chemistry. 2010 Dec;285(51):39976–85. doi: 10.1074/jbc.m110.182915.
Elongation of (very) long chain fatty acids

Accession ID: WikiPathways:WP4491
  • 10.1038/s41586-019-0904-1
 Vriens K, Christen S, Parik S, Broekaert D, Yoshinaga K, Talebi A, Dehairs J, Escalona-Noguero C, Schmieder R, Cornfield T, Charlton C, Romero-Pérez L, Rossi M, Rinaldi G, Orth MF, Boon R, Kerstens A, Kwan SY, Faubert B, Méndez-Lucas A, Kopitz CC, Chen T, Fernandez-Garcia J, Duarte JAG, Schmitz AA, Steigemann P, Najimi M, Hägebarth A, Van Ginderachter JA, Sokal E, Gotoh N, Wong KK, Verfaillie C, Derua R, Munck S, Yuneva M, Beretta L, DeBerardinis RJ, Swinnen JV, Hodson L, Cassiman D, Verslype C, Christian S, Grünewald S, Grünewald TGP, Fendt SM. Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity. Nature. 2019 Feb;566(7744):403–6. PMID: 30728499; PMCID: PMC6390935.
Mitochondrial beta-oxidation

Accession ID: WikiPathways:WP5241
  • 10.1074/jbc.m411069200
 Alphey MS, Yu W, Byres E, Li D, Hunter WN. Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site. J Biol Chem. 2005 Jan 28;280(4):3068–77. doi: 10.1074/jbc.m411069200. PMID: 15531764.
Metabolism of alpha-linolenic acid

Accession ID: WikiPathways:WP4586		 -
Omega-3 / omega-6 fatty acid synthesis

Accession ID: WikiPathways:WP4723
  • 10.1074/jbc.m110.182915
 Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, Myers DS, Glass CK, Hardiman G, Reichart D, Merrill AH, Sullards MC, Wang E, Murphy RC, Raetz CRH, Garrett TA, Guan Z, Ryan AC, Russell DW, McDonald JG, Thompson BM, Shaw WA, Sud M, Zhao Y, Gupta S, Maurya MR, Fahy E, Subramaniam S. A Mouse Macrophage Lipidome. Journal of Biological Chemistry. 2010 Dec;285(51):39976–85. doi: 10.1074/jbc.m110.182915.
Linoleic acid metabolism affected by SARS-CoV-2

Accession ID: WikiPathways:WP4853
  • 10.1038/srep13092
 Miao H, Chen L, Hao L, Zhang X, Chen Y, Ruan Z, Liang H. Stearic acid induces proinflammatory cytokine production partly through activation of lactate-HIF1a pathway in chondrocytes. Scientific Reports. 2015 Aug 14;5(1):13092. doi: 10.1038/srep13092.
Triacylglycerol Degradation TG(16:0/16:0/18:3(6Z,9Z,12Z))

Accession ID: PathBank:SMP0012473		 -
Triacylglycerol Degradation TG(16:0/18:0/18:3(6Z,9Z,12Z))

Accession ID: PathBank:SMP0012485		 -
Triacylglycerol Degradation TG(16:0/18:1(9Z)/18:3(6Z,9Z,12Z))

Accession ID: PathBank:SMP0012497		 -
Triacylglycerol Degradation TG(16:0/18:1(11Z)/18:3(6Z,9Z,12Z))

Accession ID: PathBank:SMP0012509		 -
Triacylglycerol Degradation TG(16:0/18:2(9Z,12Z)/18:3(6Z,9Z,12Z))

Accession ID: PathBank:SMP0012521		 -
Triacylglycerol Degradation TG(16:0/18:3(6Z,9Z,12Z)/18:0)

Accession ID: PathBank:SMP0012529		 -
Triacylglycerol Degradation TG(16:0/18:3(6Z,9Z,12Z)/18:3(6Z,9Z,12Z))

Accession ID: PathBank:SMP0012533		 -
Triacylglycerol Degradation TG(16:0/18:3(6Z,9Z,12Z)/20:1(13Z))

Accession ID: PathBank:SMP0012537		 -
Triacylglycerol Degradation TG(16:0/18:3(9Z,12Z,15Z)/18:3(6Z,9Z,12Z))

Accession ID: PathBank:SMP0012545		 -
Triacylglycerol Degradation TG(16:0/20:0/18:3(6Z,9Z,12Z))

Accession ID: PathBank:SMP0012557		 -
Triacylglycerol Degradation TG(16:0/20:1(11Z)/18:3(6Z,9Z,12Z))

Accession ID: PathBank:SMP0012569		 -
Triacylglycerol Degradation TG(16:0/20:1(13Z)/18:3(6Z,9Z,12Z))

Accession ID: PathBank:SMP0012581		 -
Triacylglycerol Degradation TG(16:0/22:0/18:3(6Z,9Z,12Z))

Accession ID: PathBank:SMP0012593		 -
Triacylglycerol Degradation TG(16:0/22:1(13Z)/18:3(6Z,9Z,12Z))

Accession ID: PathBank:SMP0012605		 -