Metabolite List

metabolites which its exact mass nearly 396.1970342 with tolerance error 0.01 da.

1-[2-Amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea (BioCAD00000174929)
Formula: C20H24N6O3 (Exact Mass: 396.191)

PD-166866 is a member of the class of pyridopyrimidines that is pyrido[2,3-d]pyrimidine substituted by an amino group at position 2, 3,5-dimethoxyphenyl group at position 6, and by a (tert-butylcarbamoyl)nitrilo group at position 7. It is a selective ATP competitive inhibitor of the human fibroblast growth factor-1 receptor (FGFR1) tyrosine kinase with an IC50 of 52.4 nM. It has a role as an apoptosis inducer, an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an angiogenesis inhibitor. It is a dimethoxybenzene, a pyridopyrimidine, a member of ureas, a biaryl and a primary arylamine.

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PD-166866 (BioCAD00000483965)
Formula: C20H24N6O3 (Exact Mass: 396.191)

A member of the class of pyridopyrimidines that is pyrido[2,3-d]pyrimidine substituted by an amino group at position 2, 3,5-dimethoxyphenyl group at position 6, and by a (tert-butylcarbamoyl)nitrilo group at position 7. It is a selective ATP competitive inhibitor of the human fibroblast growth factor-1 receptor (FGFR1) tyrosine kinase with an IC50 of 52.4 nM." []

LSM-21029 (BioCAD00000568916)
Formula: C19H28N2O7 (Exact Mass: 396.1896)

5-(5-acetyl-2-propoxy-3-pyridinyl)-2-(3-azetidinyl)-3-ethyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one (BioCAD00000647248)
Formula: C20H24N6O3 (Exact Mass: 396.191)

methyl (4aS,7aS)-1-(propan-2-ylcarbamoyloxy)-7-(propan-2-ylcarbamoyloxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate (BioCAD00000686275)
Formula: C19H28N2O7 (Exact Mass: 396.1896)

(S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-((1S,2S,3S,4S)-2,3,4-trihydroxy-cyclohexyl)-acetic acid ethyl ester (BioCAD00000712146)
Formula: C19H28N2O7 (Exact Mass: 396.1896)

(R)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-((1S,2S,3S,4S)-2,3,4-trihydroxy-cyclohexyl)-acetic acid ethyl ester (BioCAD00000712147)
Formula: C19H28N2O7 (Exact Mass: 396.1896)

NPD8410 (BioCAD00001576922)
Formula: C19H28N2O7 (Exact Mass: 396.1896)

AKOS030490313 (BioCAD00001588932)
Formula: C20H24N6O3 (Exact Mass: 396.191)

AKOS032448077 (BioCAD00001590644)
Formula: C20H24N6O3 (Exact Mass: 396.191)

1-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-2-[6-(dimethylamino)-9H-purin-9-yl]ethanone (BioCAD00001608709)
Formula: C20H24N6O3 (Exact Mass: 396.191)

2-[(2-HYDROXYETHYL)SULFANYL]-3-(2-METHYLPROP-2-EN-1-YL)-4,6-DIHYDRO-3H-SPIRO[BENZO[H]QUINAZOLINE-5,1'-CYCLOHEXAN]-4-ONE (BioCAD00001626000)
Formula: C23H28N2O2S (Exact Mass: 396.1871)

(BioCAD00001632714)
Formula: C20H24N6O3 (Exact Mass: 396.191)

NCGC00391416-01 (BioCAD00001634069)
Formula: C20H24N6O3 (Exact Mass: 396.191)

3-CYCLOPENTYL-2-[(2-HYDROXYETHYL)SULFANYL]-4,6-DIHYDRO-3H-SPIRO[BENZO[H]QUINAZOLINE-5,1'-CYCLOPENTAN]-4-ONE (BioCAD00001675038)
Formula: C23H28N2O2S (Exact Mass: 396.1871)

(BioCAD00001677684)
Formula: C23H28N2O2S (Exact Mass: 396.1871)

(BioCAD00001772429)
Formula: C23H28N2O2S (Exact Mass: 396.1871)

(BioCAD00001784812)
Formula: C23H28N2O2S (Exact Mass: 396.1871)

(BioCAD00001791029)
Formula: C23H28N2O2S (Exact Mass: 396.1871)

NCGC00391358-01 (BioCAD00001852845)
Formula: C23H28N2O2S (Exact Mass: 396.1871)