Delta1-Piperideine-2-carboxylate (BioCAD00000009669)
Metabolite Card
Formula: C6H9NO2 (127.0633)
SMILES: OC(=O)C1=NCCCC1
Synonyms [en]
Delta1-piperideine-2-carboxylate; delta(1)-Piperidine-2-carboxylic acid; 1-Piperideine-2-carboxylic acid; 3,4,5,6-tetrahydro-2-pyridinecarboxylic acid; D-1-Piperideine-2-carboxylic acid; 1-P-2-CA
Last reviewed on 2024-06-28.
Cite this Page
Delta1-Piperideine-2-carboxylate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000009669). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
1-Piperideine-2-carboxylic acid (P2C), also known as Δ1-pipecolic acid, is classified as a member of the tetrahydropyridines. Tetrahydropyridines are derivatives of pyridine in which two double bonds in the pyridine moiety are reduced by adding four hydrogen atoms. 1-Piperideine-2-carboxylic acid is considered to be slightly soluble (in water) and acidic. 1-Piperideine-2-carboxylic acid is an intermediate of the L-lysine metabolic pathway in the brain; the uptake of P2C into the synaptosome of the cerebral cortex was Na+ and temperature-dependent (PMID: 7654748).
DBLinks
- CAS Registry Number: 2756-89-0
- PubChem CID: 1194
- ChEBI: 30912
- HMDB: HMDB0001084
- LipidMaps:
- KEGG: C04092
- BioCyc:
- NCBI MeSH: delta(1)-piperidine-2-carboxylic acid
- Wikipedia:
Other DBLinks
- CAS Registry Number: 2756-89-0
- CAS Registry Number: 3038-89-9
- PubChem: 1194
- PubChem: 165067
- ChEBI: ChEBI:30912
- ChEBI: ChEBI:49015
- HMDB: HMDB0001084
- HMDB: HMDB01084
- KEGG: C04092
- NCBI MeSH: delta(1)-piperidine-2-carboxylic acid
- NCBI MeSH: delta-1-piperidine-6-carboxylic acid
- RefMet: RM0136054
- Metlin: METLIN_5992
- Coconut NaturalProduct: CNP0002372.0
Class / Ontology
- WishartLab ClassyFire: [Hydropyridines] Hydropyridines
- RefMet: [Amino acids] Amino acids
- ChEBI: [CHEBI:30912] 1-piperideine-2-carboxylic acid
- ChEBI: [CHEBI:49015] 1-piperideine-6-carboxylic acid
- Coconut NaturalProduct: [Aminoacids] Aminoacids
| ID | EC Number | Name |
|---|---|---|
| KEGG:R00445 | 1.4.1.15 | L-lysine:NAD+ oxidoreductase (deaminating, cyclizing) |
| KEGG:R02201 | 1.5.1.1 | L-pipecolate:NAD+ 2-oxidoreductase |
| KEGG:R02203 | 1.5.1.1 | L-pipecolate:NADP+ 2-oxidoreductase |
| KEGG:R04175 | C03239<=>C04092 + C00001 |
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| Reactome:R-BTA-1430728 | Metabolism |
| Reactome:R-BTA-71291 | Amino acid and derivative metabolism |
| Reactome:R-CFA-1430728 | Metabolism |
| Reactome:R-DRE-71291 | Amino acid and derivative metabolism |
| Reactome:R-HSA-71064 | Lysine catabolism |
| Reactome:R-MMU-1430728 | Metabolism |
| Reactome:R-MMU-71064 | Lysine catabolism |
| Reactome:R-RNO-71064 | Lysine catabolism |
| Reactome:R-SCE-71291 | Amino acid and derivative metabolism |
| Reactome:R-SPO-1430728 | Metabolism |
| Reactome:R-SSC-71064 | Lysine catabolism |
| Reactome:R-BTA-71064 | Lysine catabolism |
| Reactome:R-CFA-71291 | Amino acid and derivative metabolism |
| Reactome:R-DRE-71064 | Lysine catabolism |
| Reactome:R-DDI-71291 | Amino acid and derivative metabolism |
| Reactome:R-DME-1430728 | Metabolism |
| Reactome:R-DME-71291 | Amino acid and derivative metabolism |
| Reactome:R-GGA-71291 | Amino acid and derivative metabolism |
| Reactome:R-SCE-1430728 | Metabolism |
| Reactome:R-SCE-71064 | Lysine catabolism |