Allantoate (BioCAD00000006133)

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Metabolite Card

Formula: C4H8N4O4 (176.0546)
SMILES: NC(=O)NC(NC(N)=O)C(O)=O

Synonyms [en]

ALLANTOIC ACID; Allantoate; Diureidoacetic acid; Bis[(aminocarbonyl)amino]acetic acid; UNII-02WGT7SHWJ; Allantoicacid

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Allantoate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000006133). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Allantoic acid is the end product of Allantoicase [EC:3.5.3.4], an enzyme involved in uric acid degradation (Purine metabolism). Although it is commonly accepted that allantoicase is lost in mammals, it has been identified in mice and humans. (PMID 11852104). A crystalline, transparent, colorless substance found in the allantoic liquid of the fetal calf. It was formerly called allantoic acid and amniotic acid.

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 102185-22-8
  • CAS Registry Number: 6065-82-3
  • CAS Registry Number: 99-16-1
  • PubChem: 203
  • ChEBI: ChEBI:17536
  • ChEBI: ChEBI:30837
  • HMDB: HMDB0001209
  • KEGG: C00499
  • BioCyc: ALLANTOATE
  • NCBI MeSH: allantoic acid
  • Wikipedia: Allantoic_acid
  • RefMet: RM0136075
  • MoNA: FiehnHILIC000172
  • MoNA: FiehnHILIC001060
  • MoNA: FiehnLib001012
  • MoNA: FiehnLib001013
  • MoNA: FiehnLib001014
  • MoNA: HMDB0001209_ms_ms_1466
  • MoNA: HMDB0001209_ms_ms_1467
  • MoNA: HMDB0001209_ms_ms_1468
  • MoNA: KO000223
  • MoNA: KO000224
  • MoNA: KO000225
  • MoNA: KO000226
  • MoNA: KO000227
  • MoNA: MoNA033020
  • MoNA: MoNA033022
  • MoNA: MoNA033023
  • MoNA: MoNA035212
  • MoNA: MoNA035213
  • MoNA: MoNA035214
  • MoNA: MoNA036697
  • MoNA: MoNA036699
  • MoNA: MoNA036701
  • MoNA: MoNA037481
  • MoNA: MoNA038234
  • MoNA: MoNA038779
  • Metlin: METLIN_343
  • Coconut NaturalProduct: CNP0253215.0
  • Coconut NaturalProduct: CNP0270535.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R02422 3.5.3.4 allantoate amidinohydrolase
KEGG:R02423 3.5.3.9 allantoate amidinohydrolase (decarboxylating)
KEGG:R02425 3.5.2.5 (S)-allantoin amidohydrolase
KEGG:R12703 2.1.3.16 C00499 + C00009<=>C02091 + C00169
BioCyc:ALLANTOINASE-RXN 3.5.2.5 S-ALLANTOIN + WATER --> PROTON + ALLANTOATE
BioCyc:ALLANTOATE-DEIMINASE-RXN 3.5.3.9 2 PROTON + ALLANTOATE + WATER --> CPD0-2298 + AMMONIUM + CARBON-DIOXIDE
Rhea:RHEA:11017 3.5.3.4 allantoate + H2O => (S)-ureidoglycolate + urea
Rhea:RHEA:11018 3.5.3.4 (S)-ureidoglycolate + urea => allantoate + H2O
Rhea:RHEA:11019 3.5.3.4 allantoate + H2O <=> (S)-ureidoglycolate + urea
Rhea:RHEA:17030 3.5.2.5 (S)-allantoin + H2O => allantoate + H+
Rhea:RHEA:17031 3.5.2.5 allantoate + H+ => (S)-allantoin + H2O
Rhea:RHEA:17032 3.5.2.5 (S)-allantoin + H2O <=> allantoate + H+
Rhea:RHEA:27486 3.5.3.9 allantoate + H2O + 2 H+ => (S)-2-ureidoglycine + NH4+ + CO2
Rhea:RHEA:27487 3.5.3.9 (S)-2-ureidoglycine + NH4+ + CO2 => allantoate + H2O + 2 H+
Rhea:RHEA:27488 3.5.3.9 allantoate + H2O + 2 H+ <=> (S)-2-ureidoglycine + NH4+ + CO2
Rhea:RHEA:30820 allantoin + H2O => allantoate + H+
Rhea:RHEA:30821 allantoate + H+ => allantoin + H2O
Rhea:RHEA:30822 allantoin + H2O <=> allantoate + H+
Rhea:RHEA:32280 allantoate + 2 H2O + 2 H+ => (S)-ureidoglycolate + 2 NH4+ + CO2
Rhea:RHEA:32281 (S)-ureidoglycolate + 2 NH4+ + CO2 => allantoate + 2 H2O + 2 H+
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Organism Source

Taxonomy Source

  1. Arabidopsis thaliana [ncbi taxid: 3702]
  2. Chlamydomonas reinhardtii [ncbi taxid: 3055]
  3. Citrullus lanatus [ncbi taxid: 3654]
  4. Glycine max [ncbi taxid: 3847]
  5. Homo sapiens [ncbi taxid: 9606]
  6. Robinia pseudoacacia [ncbi taxid: 35938]
  7. Saccharomyces cerevisiae [ncbi taxid: 4932]
  8. Wisteria sinensis [ncbi taxid: 20997]

Pathway Synthetic

pathway id name
PathBank:SMP0000847 Glycolate and Glyoxylate Degradation
PathBank:SMP0002064 Allantoin Degradation (Anaerobic)
Plant Reactome:R-OAU-2744345 Metabolism and regulation
Plant Reactome:R-FVE-5096066 Amine and polyamine biosynthesis
Plant Reactome:R-MES-2744345 Metabolism and regulation
Plant Reactome:R-MES-1119502 Allantoin assimilation
Plant Reactome:R-MES-1119407 ureide biogenesis
Plant Reactome:R-TDI-2744345 Metabolism and regulation
Plant Reactome:R-TDI-5096066 Amine and polyamine biosynthesis
Plant Reactome:R-TDI-5655149 Nucleotide metabolism
Plant Reactome:R-OGU-5096066 Amine and polyamine biosynthesis
Plant Reactome:R-OGU-5655149 Nucleotide metabolism
Plant Reactome:R-OMI-1119407 ureide biogenesis
Plant Reactome:R-PTI-2744345 Metabolism and regulation
Plant Reactome:R-PTI-1119502 Allantoin assimilation
Plant Reactome:R-GMA-2744345 Metabolism and regulation
Plant Reactome:R-GMA-5096066 Amine and polyamine biosynthesis
Plant Reactome:R-GMA-1119407 ureide biogenesis
Plant Reactome:R-PVU-2744345 Metabolism and regulation
Plant Reactome:R-PVU-5096066 Amine and polyamine biosynthesis
View All Pathways