4-Trimethylammoniobutanal (BioCAD00000004558)

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Metabolite Card

Formula: C7H16NO (130.1232)
SMILES: C[N+](C)(C)CCCC=O

Synonyms [en]

4-Trimethylammoniobutanal; 4-(trimethylamino)butanal; trimethyl-(4-oxobutyl)ammonium; Trimethylaminobutyraldehyde; N,N,N-trimethyl-4-oxobutan-1-aminium; gamma-trimethylaminobutyraldehyde

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

4-Trimethylammoniobutanal. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000004558). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

4-Trimethylammoniobutanal is a substrate for Serine hydroxymethyltransferase (cytosolic), Serine hydroxymethyltransferase (mitochondrial), Aldehyde dehydrogenase (mitochondrial), Fatty aldehyde dehydrogenase, 4-trimethylaminobutyraldehyde dehydrogenase, Aldehyde dehydrogenase (dimeric NADP-preferring), Aldehyde dehydrogenase family 7 member A1, Aldehyde dehydrogenase 1A3 and Aldehyde dehydrogenase X (mitochondrial).

Cytoplasm Mitochondria
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 64595-66-0
  • PubChem: 133
  • ChEBI: ChEBI:18020
  • HMDB: HMDB0001345
  • KEGG: C01149
  • BioCyc: 4-TRIMETHYLAMMONIOBUTANAL
  • NCBI MeSH: gamma-trimethylaminobutyraldehyde
  • Coconut NaturalProduct: CNP0530420.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R03283 1.2.1.3 4-trimethylammoniobutanal:NAD+ 1-oxidoreductase;
KEGG:R03284 4.1.2.- C01149 + C00037<=>C01259
Rhea:RHEA:17986 1.2.1.47 4-(trimethylamino)butanal + NAD+ + H2O => 4-(trimethylamino)butanoate + NADH + 2 H+
Rhea:RHEA:17987 1.2.1.47 4-(trimethylamino)butanoate + NADH + 2 H+ => 4-(trimethylamino)butanal + NAD+ + H2O
Rhea:RHEA:17988 1.2.1.47 4-(trimethylamino)butanal + NAD+ + H2O <=> 4-(trimethylamino)butanoate + NADH + 2 H+
Rhea:RHEA:79696 (3S)-3-hydroxy-N6,N6,N6-trimethyl-L-lysine => 4-(trimethylamino)butanal + glycine
Rhea:RHEA:79697 4-(trimethylamino)butanal + glycine => (3S)-3-hydroxy-N6,N6,N6-trimethyl-L-lysine
Rhea:RHEA:79698 (3S)-3-hydroxy-N6,N6,N6-trimethyl-L-lysine <=> 4-(trimethylamino)butanal + glycine
BioCyc:RXN-9896 3-HYDROXY-N6N6N6-TRIMETHYL-L-LYSINE --> 4-TRIMETHYLAMMONIOBUTANAL + GLY
BioCyc:1.2.1.47-RXN 1.2.1.47 4-TRIMETHYLAMMONIOBUTANAL + NAD + WATER --> GAMMA-BUTYROBETAINE + NADH + 2 PROTON
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Organism Source

Taxonomy Source

  1. Homo sapiens [ncbi taxid: 9606]
  2. Mus musculus [ncbi taxid: 10090]

Pathway Synthetic

pathway id name
BioCyc:META_PWY-6100 L-carnitine biosynthesis
BioCyc:HUMAN_PWY-6100 L-carnitine biosynthesis
BioCyc:MOUSE_PWY-6100 L-carnitine biosynthesis
BioCyc:FLY_PWY-6100 L-carnitine biosynthesis
PlantCyc:CROSEUS_PWY-6100 L-carnitine biosynthesis
PlantCyc:TPARVULA_PWY-6100 L-carnitine biosynthesis
PlantCyc:CORKOAK_PWY-6100 L-carnitine biosynthesis
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-71291 Amino acid and derivative metabolism
Reactome:R-BTA-71262 Carnitine synthesis
Reactome:R-CFA-1430728 Metabolism
Reactome:R-DRE-71291 Amino acid and derivative metabolism
Reactome:R-DRE-71262 Carnitine synthesis
Reactome:R-MMU-1430728 Metabolism
Reactome:R-SCE-71291 Amino acid and derivative metabolism
Reactome:R-SCE-71262 Carnitine synthesis
Reactome:R-SPO-1430728 Metabolism
Reactome:R-CFA-71291 Amino acid and derivative metabolism
Reactome:R-CFA-71262 Carnitine synthesis
Reactome:R-DME-1430728 Metabolism
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