3beta-Hydroxypregn-5-en-20-one sulfate (BioCAD00000004124)

blood urine kidney liver

Metabolite Card

Formula: C21H32O5S (396.197)
SMILES: CC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OS(O)(=O)=O

Synonyms [en]

pregnenolone sulfate; (3beta)-3-(sulfooxy)pregn-5-en-20-one; 3beta-Hydroxypregn-5-en-20-one sulfate; 5-Pregnen-3beta-ol-20-one sulfate; 20-oxopregn-5-en-3beta-yl sulfate; 3beta-Hydroxy-5-pregnen-20-one monosulfate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

3beta-Hydroxypregn-5-en-20-one sulfate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000004124). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

3beta-Hydroxypregn-5-en-20-one sulfate is a metabolite of pregnenolone. Pregnenolone, also known as 3α,5β-tetrahydroprogesterone (3α,5β-THP), is an endogenous steroid hormone involved in the steroidogenesis of progestogens, mineralocorticoids, glucocorticoids, androgens, and estrogens, as well as the neuroactive steroids. As such it is a prohormone, though it also has biological effects of its own, behaving namely as a neuroactive steroid in its own right with potent anxiolytic effects. (Wikipedia)

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 1247-64-9
  • PubChem: 105074
  • ChEBI: ChEBI:35420
  • HMDB: HMDB0060382
  • LipidMaps: LMST05020014
  • KEGG: C18044
  • NCBI MeSH: pregnenolone sulfate
  • Wikipedia: Pregnenolone sulfate
  • Wikipedia: Pregnenolone_sulfate
  • RefMet: RM0138917
  • Coconut NaturalProduct: CNP0218718.2

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R08942 3.1.6.2 pregnenolone-sulfate sulfohydrolase;
KEGG:R08978 2.8.2.2 3'-phosphoadenylyl-sulfate:pregnenolone sulfotransferase
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
Reactome:R-BTA-1430728 Metabolism
Reactome:R-CEL-211859 Biological oxidations
Reactome:R-CEL-156584 Cytosolic sulfonation of small molecules
Reactome:R-CFA-1430728 Metabolism
Reactome:R-CFA-156580 Phase II - Conjugation of compounds
Reactome:R-DRE-156584 Cytosolic sulfonation of small molecules
Reactome:R-GGA-156580 Phase II - Conjugation of compounds
Reactome:R-HSA-211859 Biological oxidations
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-211859 Biological oxidations
Reactome:R-XTR-156584 Cytosolic sulfonation of small molecules
Reactome:R-BTA-211859 Biological oxidations
Reactome:R-CFA-156584 Cytosolic sulfonation of small molecules
Reactome:R-GGA-156584 Cytosolic sulfonation of small molecules
Reactome:R-HSA-156580 Phase II - Conjugation of compounds
Reactome:R-MMU-156580 Phase II - Conjugation of compounds
Reactome:R-RNO-211859 Biological oxidations
Reactome:R-SSC-1430728 Metabolism
Reactome:R-SSC-211859 Biological oxidations
Reactome:R-BTA-156584 Cytosolic sulfonation of small molecules
View All Pathways