3-Phosphonooxypyruvate (BioCAD00000003800)

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Metabolite Card

Formula: C3H5O7P (183.9773)
SMILES: OC(=O)C(=O)COP(O)(O)=O

Synonyms [en]

3-phosphonooxypyruvate; Phosphohydroxypyruvic acid; 3-Phosphonooxypyruvic acid; 3-Phosphohydroxypyruvic acid; Hydroxypyruvic acid phosphate; 3-phosphohydroxypyruvate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

3-Phosphonooxypyruvate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000003800). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Phosphohydroxypyruvic acid is a prduct of both enzyme phosphoglycerate dehydrogenase [EC 1.1.1.95] and phosphoserine transaminase [EC 2.6.1.52] in glycine, serine and threonine metabolism pathway (KEGG). This compound belongs to the family of Organophosphate Esters. These are organic compounds containing phosphoric acid ester functional group.

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 114887-36-4
  • CAS Registry Number: 3913-50-6
  • PubChem: 105
  • ChEBI: ChEBI:18110
  • ChEBI: ChEBI:30933
  • HMDB: HMDB0001024
  • KEGG: C03232
  • NCBI MeSH: phosphohydroxypyruvic acid
  • Wikipedia: Phosphohydroxypyruvic acid
  • Wikipedia: Phosphohydroxypyruvic_acid
  • RefMet: RM0136053
  • Metlin: METLIN_484
  • Coconut NaturalProduct: CNP0359853.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R01513 1.1.1.95 3-phospho-D-glycerate:NAD+ 2-oxidoreductase
KEGG:R04173 2.6.1.52 3-phosphoserine:2-oxoglutarate aminotransferase
Rhea:RHEA:12642 1.1.1.95 (2R)-3-phosphoglycerate + NAD+ => 3-phosphooxypyruvate + NADH + H+
Rhea:RHEA:12643 1.1.1.95 3-phosphooxypyruvate + NADH + H+ => (2R)-3-phosphoglycerate + NAD+
Rhea:RHEA:12644 1.1.1.95 (2R)-3-phosphoglycerate + NAD+ <=> 3-phosphooxypyruvate + NADH + H+
Rhea:RHEA:14330 2.6.1.52 O-phospho-L-serine + 2-oxoglutarate => 3-phosphooxypyruvate + L-glutamate
Rhea:RHEA:14331 2.6.1.52 3-phosphooxypyruvate + L-glutamate => O-phospho-L-serine + 2-oxoglutarate
Rhea:RHEA:14332 2.6.1.52 O-phospho-L-serine + 2-oxoglutarate <=> 3-phosphooxypyruvate + L-glutamate
Rhea:RHEA:35544 3-phosphooxypyruvate + H2O => 3-hydroxypyruvate + phosphate
Rhea:RHEA:35545 3-hydroxypyruvate + phosphate => 3-phosphooxypyruvate + H2O
Rhea:RHEA:35546 3-phosphooxypyruvate + H2O <=> 3-hydroxypyruvate + phosphate
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Organism Source

Taxonomy Source

  1. Citrullus lanatus [ncbi taxid: 3654]
  2. Escherichia coli [ncbi taxid: 562]
  3. Homo sapiens [ncbi taxid: 9606]
  4. Saccharomyces cerevisiae [ncbi taxid: 4932]

Pathway Synthetic

pathway id name
PathBank:SMP0000821 Cysteine Biosynthesis
PathBank:SMP0000829 Serine Biosynthesis and Metabolism
PathBank:SMP0000993 Secondary Metabolites: Cysteine Biosynthesis from Serine
WikiPathways:WP2525 Trans-sulfuration, one-carbon metabolism and related pathways
WikiPathways:WP3604 Biochemical pathways: part I
WikiPathways:WP5355 Metabolic Epileptic Disorders
WikiPathways:WP3135 Trans-sulfuration and one-carbon metabolism
PathBank:SMP0120694 Dihydropyrimidine Dehydrogenase Deficiency (DHPD)
PathBank:SMP0120754 Non-Ketotic Hyperglycinemia
PathBank:SMP0120770 Hyperglycinemia, Non-Ketotic
PathBank:SMP0000242 Dimethylglycine Dehydrogenase Deficiency
PathBank:SMP0000223 Non-Ketotic Hyperglycinemia
PathBank:SMP0000484 Dimethylglycine Dehydrogenase Deficiency
PathBank:SMP0087338 Glycine and Serine Metabolism
PathBank:SMP0087466 Glycine and Serine Metabolism
PathBank:SMP0120653 3-Phosphoglycerate Dehydrogenase Deficiency
PathBank:SMP0120741 Sarcosinemia
PathBank:SMP0120475 Dimethylglycine Dehydrogenase Deficiency
PathBank:SMP0000004 Glycine and Serine Metabolism
PathBank:SMP0000721 3-Phosphoglycerate Dehydrogenase Deficiency
View All Pathways