2-Aminomuconate (BioCAD00000002349)
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Metabolite Card
Formula: C6H7NO4 (157.0375)
SMILES: N\C(=C\C=C/C(O)=O)C(O)=O
Synonyms [en]
2-Aminomuconic acid; 2-aminohexa-2,4-dienedioic acid; 2-Aminomuconate; 2-amino-2,4-hexadienedioic acid; (2E,4Z)-2-Aminohexa-2,4-dienedioic acid; alpha-aminomuconic acid
Last reviewed on 2024-06-28.
Cite this Page
2-Aminomuconate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000002349). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
2-Aminomuconic acid is a product of the Tryptophan metabolism degradation pathway (kinurenine pathway), in a reaction catabolized by the enzyme aminocarboxymuconate semialdehyde decarboxylase [EC:4.1.1.45]. The kynurenine pathway is the major route of L-tryptophan degradation in mammals. (BioCyc).
DBLinks
- CAS Registry Number: 4548-99-6
- PubChem CID: 5280499
- ChEBI: 16886
- HMDB: HMDB0001241
- LipidMaps: LMFA01170082
- KEGG: C02220
- BioCyc:
- NCBI MeSH:
- Wikipedia: 2-Aminomuconic acid
Other DBLinks
- CAS Registry Number: 4548-99-6
- PubChem: 5280499
- PubChem: 5459864
- ChEBI: ChEBI:15745
- ChEBI: ChEBI:16886
- ChEBI: ChEBI:189698
- HMDB: HMDB0001241
- LipidMaps: LMFA01170082
- KEGG: C02220
- Wikipedia: 2-Aminomuconic acid
- Wikipedia: 2-Aminomuconic_acid
- RefMet: RM0131450
- Metlin: METLIN_45922
- Coconut NaturalProduct: CNP0360097.0
Class / Ontology
- WishartLab ClassyFire: [Amino acids, peptides, and analogues] Amino acids, peptides, and analogues
- RefMet: [Amino acids] Amino acids
- LipidMaps: [Dicarboxylic acids [FA0117]] Dicarboxylic acids [FA0117]
- ChEBI: [CHEBI:16886] 2-aminomuconic acid
- ChEBI: [CHEBI:189698] (2E,4Z)-2-aminomuconic acid
- Coconut NaturalProduct: [Aminoacids] Aminoacids
| ID | EC Number | Name |
|---|---|---|
| KEGG:R01937 | 1.5.1.- | C00322 + C00014 + C00003<=>C02220 + C00004 + C00080 + C00001 |
| KEGG:R01938 | 1.5.1.- | C00322 + C00014 + C00006<=>C02220 + C00005 + C00080 + C00001 |
| KEGG:R03887 | 3.5.99.5 | 2-aminomuconate aminohydrolase |
| KEGG:R03889 | 1.2.1.32 | 2-aminomuconate semialdehyde:NAD+ 6-oxidoreductase |
| KEGG:R11532 | 3.5.99.11 | 2-aminomuconate aminohydrolase (2-hydroxymuconate-forming) |
Taxonomy Source
- Homo sapiens [ncbi taxid: 9606]
- Mus musculus [ncbi taxid: 10090]
- Pseudomonas pseudoalcaligenes [ncbi taxid: ]
Pathway Synthetic
| pathway id | name |
|---|---|
| WikiPathways:WP3604 | Biochemical pathways: part I |
| WikiPathways:WP465 | Tryptophan metabolism |
| PathBank:SMP0121131 | 2-Amino-3-Carboxymuconate Semialdehyde Degradation |