Sulcatone (BioCAD00000018078)

breath feces saliva plant natural products microbial natural products

Metabolite Card

Formula: C8H14O (126.1045)
SMILES: CC(C)=CCCC(C)=O

Synonyms [en]

6-methyl-5-hepten-2-one; sulcatone; methylheptenone; 6-Methylhept-5-en-2-one; 6-methylheptan-5-ene-2-one; 2-methylhept-2-en-6-one

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Sulcatone. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000018078). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Sulcatone, also known as methylheptenone or fema 2707, belongs to the class of organic compounds known as ketones. These are organic compounds in which a carbonyl group is bonded to two carbon atoms R2C=O (neither R may be a hydrogen atom). Ketones that have one or more alpha-hydrogen atoms undergo keto-enol tautomerization, the tautomer being an enol. Sulcatone is a very hydrophobic methylketone, practically insoluble in water, and relatively neutral. It exists as a clear, colorless liquid. Sulcatone can be found in all eukaryotes, ranging from yeast to plants to humans. Sulcatone has a musty, apple green-bean, and pear-like taste. and a citrus-like lemongrass odor. It is a volatile oil component of citronella oil, lemon-grass oil and palmarosa oil. Sulcatone is naturally found in bay leaf, blackberry fruit, sour cherries, cloves, ginger and lavender. In insects and animals, it has a role as an alarm or attractant pheromone. In fact, sulcatone is one of a number of mosquito attractants, especially for those species such as Aedes aegypti with the odor receptor gene Or4 (PMID:25391959 ). Sulcatone is secreted by humans in their sweat and is a compound frequently found in human body odors (but in few other mammals). Sulcoatone is used as a pheromone by ferrets, european badgers, red foxes, treefrogs, bedbugs, wasps and butterflies. Sulcatone is one of several ketones found in Cannabis sativa (PMID:6991645 ).

Cytoplasm Extracellular Membrane
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 110-93-0
  • CAS Registry Number: 14129-48-7
  • CAS Registry Number: 1502-38-1
  • CAS Registry Number: 21889-89-4
  • CAS Registry Number: 409-02-9
  • PubChem: 9862
  • ChEBI: ChEBI:16310
  • ChEBI: ChEBI:177003
  • HMDB: HMDB0035915
  • LipidMaps: LMFA12000039
  • KEGG: C07287
  • BioCyc: CPD-7969
  • NCBI MeSH: methylheptenone
  • Wikipedia: Sulcatone
  • RefMet: RM0135017
  • MoNA: HMDB0035915_c_ms_101774
  • MoNA: JP007035
  • Metlin: METLIN_265042
  • Metlin: METLIN_44779
  • Coconut NaturalProduct: CNP0330890.0
  • Coconut NaturalProduct: CNP0421481.0
  • Coconut NaturalProduct: CNP0566501.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R05678 1.1.1.260 sulcatol:NAD+ oxidoreductase
Rhea:RHEA:24485 1.1.1.260 sulcatol + NAD+ => sulcatone + NADH + H+
Rhea:RHEA:24486 1.1.1.260 sulcatone + NADH + H+ => sulcatol + NAD+
Rhea:RHEA:24487 1.1.1.260 sulcatol + NAD+ <=> sulcatone + NADH + H+
Rhea:RHEA:54865 sulcatone + NADPH + O2 + H+ => 4-methylpent-3-en-1-yl acetate + NADP+ + H2O
Rhea:RHEA:54866 4-methylpent-3-en-1-yl acetate + NADP+ + H2O => sulcatone + NADPH + O2 + H+
Rhea:RHEA:54867 sulcatone + NADPH + O2 + H+ <=> 4-methylpent-3-en-1-yl acetate + NADP+ + H2O
BioCyc:RXN-11972 CPD-9762 + WATER --> CPD-7969 + ACETALD
BioCyc:RXN-12396 CPD1F-114 + 2 OXYGEN-MOLECULE --> CPD-13371 + CPD-13373 + CPD-7969
BioCyc:1.1.1.260-RXN 1.1.1.260 NAD + CPD-8169<=>CPD-7969 + PROTON + NADH
BioCyc:RXN-8236 1.13.12.- CPD1F-114 + 2 OXYGEN-MOLECULE --> 2 CPD-7969 + CPD-7968
BioCyc:RXN-11971 geranal lyase
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Organism Source

Taxonomy Source

  1. Aceriphyllum rossii [ncbi taxid: ]
  2. Actaea dahurica [ncbi taxid: 64029]
  3. Actaea heracleifolia [ncbi taxid: 64034]
  4. Actaea simplex [ncbi taxid: 64042]
  5. Agnorhiza bolanderi [ncbi taxid: 230216]
  6. Akebia quinata [ncbi taxid: 13331]
  7. Akebia trifoliata [ncbi taxid: 155132]
  8. Alangium premnifolium [ncbi taxid: 2918396]
  9. Alligator mississippiensis [ncbi taxid: 8496]
  10. Anaxagorea clavata [ncbi taxid: ]
  11. Angelica acutiloba [ncbi taxid: 55605]
  12. Angelica gigas [ncbi taxid: 85712]
  13. Angelica sinensis [ncbi taxid: 165353]
  14. Angelica tarokoensis [ncbi taxid: 2831630]
  15. Araujia sericifera [ncbi taxid: 63463]
  16. Aria pallescens [ncbi taxid: ]
  17. Arnica nevadensis [ncbi taxid: 436208]
  18. Artemisia argyi [ncbi taxid: 259893]
  19. Artemisia capillaris [ncbi taxid: 265783]
  20. Artemisia monogyna [ncbi taxid: 1903222]
  21. Artemisia montana [ncbi taxid: 669134]
  22. Artemisia princeps [ncbi taxid: 223870]
  23. Backhousia angustifolia [ncbi taxid: 1288326]
  24. Backhousia citriodora [ncbi taxid: 39976]
  25. Bassia butyracea [ncbi taxid: ]
  26. Beyeria brevifolia [ncbi taxid: 2752376]
  27. Bombax ceiba [ncbi taxid: 45325]
  28. Bragantia wallichii [ncbi taxid: ]
  29. Bursaria spinosa [ncbi taxid: 105281]
  30. Calothrix & Plectonema sp. [ncbi taxid: ]
  31. Campylobacter jejuni [ncbi taxid: 197]
  32. Capsicum annuum [ncbi taxid: 4072]
  33. Chloranthus tianmushanensis [ncbi taxid: ]
  34. Chromolaena odorata [ncbi taxid: 103745]
  35. Chromolaena pulchella [ncbi taxid: ]
  36. Cimicifuga foetida [ncbi taxid: ]
  37. Cinamomum cassia [ncbi taxid: ]
  38. Cinnamomum aromaticum [ncbi taxid: 119260]
  39. Citrullus lanatus [ncbi taxid: 3654]
  40. Citrullus lanatus subsp. vulgaris [ncbi taxid: ]
  41. Citrus aurantifolia [ncbi taxid: ]
  42. Citrus aurantium [ncbi taxid: ]
  43. Citrus grandis [ncbi taxid: ]
  44. Citrus hystrix [ncbi taxid: 170989]
  45. Citrus limon [ncbi taxid: ]
  46. Citrus medica var. sarcodactylis [ncbi taxid: 381790]
  47. Citrus paradisi [ncbi taxid: ]
  48. Citrus reticulata [ncbi taxid: 85571]
  49. Citrus sinensis [ncbi taxid: 2711]
  50. Cladonia evansii [ncbi taxid: 197026]
  51. Clonostachys rosea [ncbi taxid: 29856]
  52. Clostridium difficile [ncbi taxid: ]
  53. Coccus fagi [ncbi taxid: ]
  54. Colobocentrotus atratus [ncbi taxid: 39290]
  55. Commiphora quadricincta [ncbi taxid: 2248429]
  56. Craibiodendron yunnanese [ncbi taxid: ]
  57. Crataegus pinnatifida [ncbi taxid: 510735]
  58. Crocus sativus [ncbi taxid: 82528]
  59. Daucus carota [ncbi taxid: 4039]
  60. Delphinium andersoni [ncbi taxid: ]
  61. Dendrosenecio kilimanjari [ncbi taxid: 109559]
  62. Diphasia angolensis [ncbi taxid: ]
  63. Dipterocarpus alatus [ncbi taxid: 340438]
  64. Drosera peltata [ncbi taxid: 4369]
  65. Echinops amplexicaulis [ncbi taxid: 910522]
  66. Elettaria cardamomum [ncbi taxid: 105181]
  67. Elsholtzia ciliata [ncbi taxid: 662901]
  68. Epaltes gariepina [ncbi taxid: 1548596]
  69. Ephedra sinica [ncbi taxid: 33152]
  70. Epimedium davidii [ncbi taxid: 253605]
  71. Erysimum odoratum [ncbi taxid: 1137569]
  72. Eucheuma muricatum [ncbi taxid: ]
  73. Eupolyphaga sinensis [ncbi taxid: 367774]
  74. Eutypella scoparia [ncbi taxid: ]
  75. Exodermis poria [ncbi taxid: ]
  76. Ficus formosana [ncbi taxid: 1127366]
  77. Fragaria x ananassa [ncbi taxid: 3747]
  78. Frullania tamarisci [ncbi taxid: 95764]
  79. Fusarium gibbosum [ncbi taxid: 2126134]
  80. Galenia africana [ncbi taxid: ]
  81. Ganoderma lucidum [ncbi taxid: 5315]
  82. Gardenia fosbergii [ncbi taxid: ]
  83. Globba malaccensis [ncbi taxid: ]
  84. Gnidia lamprantha [ncbi taxid: ]
  85. Hericium erinaceus [ncbi taxid: 91752]
  86. Hesperis matronalis [ncbi taxid: 264418]
  87. Heterotheca inuloides [ncbi taxid: 3015714]
  88. Hippophae rhamnoides [ncbi taxid: 193516]
  89. Homo sapiens [ncbi taxid: 9606]
  90. Humulus lupulus [ncbi taxid: 3486]
  91. Hypericum perforatum [ncbi taxid: 65561]
  92. Ilex affinis [ncbi taxid: 185489]
  93. Ilex amara [ncbi taxid: 185490]
  94. Iridomyrmex purpureus [ncbi taxid: 561532]
  95. Isodon japonicus [ncbi taxid: 425908]
  96. Isodon kameba [ncbi taxid: ]
  97. Ixora chinensis [ncbi taxid: 591727]
  98. Kaempferia pulchra [ncbi taxid: 199647]
  99. Knightia excelsa [ncbi taxid: 35944]
  100. Kobus ellipsiprymnus [ncbi taxid: 9962]
  101. Lactarius scrobiculatus [ncbi taxid: 93011]
  102. Laurencia distichophylla [ncbi taxid: ]
  103. Laurus nobilis L. [ncbi taxid: ]
  104. Leonurus glaucescens [ncbi taxid: 445399]
  105. Lepidium draba [ncbi taxid: 153317]
  106. Litsea cubeba [ncbi taxid: 155299]
  107. Maba buxifolia [ncbi taxid: ]
  108. Magnolia liliflora [ncbi taxid: ]
  109. Magnolia liliiflora [ncbi taxid: 3403]
  110. Mentha x piperita [ncbi taxid: 34256]
  111. Micromeria pineolens [ncbi taxid: 306397]
  112. Mosla chinensis [ncbi taxid: 516065]
  113. Nelumbo nucifera [ncbi taxid: 4432]
  114. Nemalion vermiculare [ncbi taxid: 935621]
  115. Nidula candida [ncbi taxid: 1348642]
  116. Odixia angusta [ncbi taxid: 125740]
  117. Ophiocoma scolopendrina [ncbi taxid: 1365868]
  118. Penicillium citreonigrum [ncbi taxid: 69768]
  119. Perilla frutescens var. arguta [ncbi taxid: 381201]
  120. Pheidole pallidula [ncbi taxid: 190770]
  121. Piper cubeba [ncbi taxid: 405322]
  122. Prosopis glandulosa [ncbi taxid: ]
  123. Prunus armeniaca [ncbi taxid: 36596]
  124. Prunus armeniaca L. (K604-19,K113-40,K33-81) [ncbi taxid: ]
  125. Prunus laurocerasus [ncbi taxid: 32242]
  126. Pseudoconidiaphora coerulescens [ncbi taxid: ]
  127. Pseudopterogorgia kallos [ncbi taxid: ]
  128. Pteris prolifera [ncbi taxid: ]
  129. Pterocarpus grandiflorus [ncbi taxid: ]
  130. Pyrosoma giganteum [ncbi taxid: ]
  131. Quercus aegilops [ncbi taxid: ]
  132. Quercus sessiliflora [ncbi taxid: ]
  133. Radix et rhizoma rhodiolae [ncbi taxid: ]
  134. Rhizobium phaseoli [ncbi taxid: 396]
  135. Rhodiola crenulata [ncbi taxid: 242839]
  136. Rhodiola rosea L. [ncbi taxid: ]
  137. Salacia madagascariensis [ncbi taxid: 670374]
  138. Salvia officinalis [ncbi taxid: 38868]
  139. Saussurea carthamoides [ncbi taxid: ]
  140. Securidaca inappendiculata [ncbi taxid: 3091905]
  141. Senecio squalidus [ncbi taxid: 121554]
  142. Senna alexandrina [ncbi taxid: 72402]
  143. Seriphidium cinum [ncbi taxid: ]
  144. Sesbania punicea [ncbi taxid: 543741]
  145. Simira eliezeriana [ncbi taxid: ]
  146. Solanum acaule [ncbi taxid: 103871]
  147. Solanum lycopersicum [ncbi taxid: 4081]
  148. Spodoptera eridania [ncbi taxid: 37547]
  149. Stenostomum lucidum [ncbi taxid: 43446]
  150. Streptomyces althioticus [ncbi taxid: 83380]
  151. Streptomyces griseovariabilis [ncbi taxid: 284636]
  152. Styrax benzoin [ncbi taxid: 153524]
  153. Succinus [ncbi taxid: ]
  154. Swertia delavayi [ncbi taxid: 166617]
  155. Taxodium mucronatum [ncbi taxid: 99812]
  156. Vaccinium vitis-idaea [ncbi taxid: 180772]
  157. Vallota purpurea [ncbi taxid: ]
  158. Vismia jefensis [ncbi taxid: ]
  159. Vitex madiensis [ncbi taxid: 1899206]
  160. Zanthoxylum bungeanum [ncbi taxid: 328401]
  161. Zanthoxylum piperitum [ncbi taxid: 354529]
  162. Zanthoxylum schinifolium [ncbi taxid: 354530]
  163. Zingiber officinale [ncbi taxid: 94328]
  164. Angelica dahurica [ncbi taxid: 48101]
  165. Eucalyptus camaldulensis [ncbi taxid: 34316]

Pathway Synthetic

pathway id name
BioCyc:META_PWY-6678 geraniol and nerol degradation
BioCyc:META_PWY-5305 bixin biosynthesis
BioCyc:META_PWY-6806 carotenoid cleavage
BioCyc:ARA_PWY-6806 carotenoid cleavage
Plant Reactome:R-OSA-2744345 Metabolism and regulation
Plant Reactome:R-OSA-2744344 Secondary metabolism
Plant Reactome:R-OSA-9609352 Lycopene cleavage
PlantCyc:SVIRIDIS_PWY-5305 bixin biosynthesis
PlantCyc:ASPARAGUS_PWY-5305 bixin biosynthesis
PlantCyc:CORN_PWY-6806 carotenoid cleavage
PlantCyc:LJAPONICUS_PWY-5305 bixin biosynthesis
PlantCyc:LER_PWY-6806 carotenoid cleavage
PlantCyc:ORYZA_PWY-5305 bixin biosynthesis
PlantCyc:PLANT_PWY-6806 carotenoid cleavage
PlantCyc:ARA_PWY-6806 carotenoid cleavage
PlantCyc:BREADWHEAT_PWY-5305 bixin biosynthesis
PlantCyc:DROTUNDATA_PWY-5305 bixin biosynthesis
PlantCyc:PLANT_PWY-5305 bixin biosynthesis
PlantCyc:SOY_PWY-5305 bixin biosynthesis
PlantCyc:ACOERULEA_PWY-5305 bixin biosynthesis
View All Pathways