Methyl ethyl ketone (BioCAD00000014001)

blood breath feces saliva urine epidermis pancreas

Metabolite Card

Formula: C4H8O (72.0575)
SMILES: CCC(C)=O

Synonyms [en]

Butanone; methyl ethyl ketone; 2-butanone; Butan-2-one; ethyl methyl ketone; methylacetone

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Methyl ethyl ketone. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000014001). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Butanone occurs as a natural product. It is made by some trees and found in some fruits and vegetables in small amounts. It is also released to the air from car and truck exhausts. The known health effects to people from exposure to butanone are irritation of the nose, throat, skin, and eyes. (wikipedia).

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 2919-23-5
  • CAS Registry Number: 78-93-3
  • PubChem: 6569
  • ChEBI: ChEBI:28398
  • HMDB: HMDB0000474
  • HMDB: HMDB00474
  • LipidMaps: LMFA12000043
  • KEGG: C02845
  • BioCyc: MEK
  • NCBI MeSH: methylethyl ketone
  • Wikipedia: Butanone
  • RefMet: RM0135018
  • MoNA: HMDB0000474_c_ms_99572
  • MoNA: HMDB0000474_c_ms_99573
  • MoNA: HMDB0000474_c_ms_99574
  • MoNA: HMDB0000474_ms_ms_692
  • MoNA: HMDB0000474_ms_ms_693
  • MoNA: HMDB0000474_ms_ms_694
  • MoNA: JP001803
  • MoNA: JP006442
  • MoNA: JP008197
  • MoNA: PS103301
  • Metlin: METLIN_4138
  • Coconut NaturalProduct: CNP0486447.0
  • Coconut NaturalProduct: CNP0562500.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R09358 4.1.2.46 (2R)-2-hydroxy-2-methylbutanenitrile butan-2-one-lyase (cyanide forming)
Rhea:RHEA:28171 4.1.2.46 (2R)-2-hydroxy-2-methylbutanenitrile => butan-2-one + hydrogen cyanide
Rhea:RHEA:28172 4.1.2.46 butan-2-one + hydrogen cyanide => (2R)-2-hydroxy-2-methylbutanenitrile
Rhea:RHEA:28173 4.1.2.46 (2R)-2-hydroxy-2-methylbutanenitrile <=> butan-2-one + hydrogen cyanide
Rhea:RHEA:55793 butan-2-one + NADH + O2 + H+ => 1-hydroxy-2-butanone + NAD+ + H2O
Rhea:RHEA:55794 1-hydroxy-2-butanone + NAD+ + H2O => butan-2-one + NADH + O2 + H+
Rhea:RHEA:55795 butan-2-one + NADH + O2 + H+ <=> 1-hydroxy-2-butanone + NAD+ + H2O
Rhea:RHEA:64561 butan-2-ol + NAD+ => butan-2-one + NADH + H+
Rhea:RHEA:64562 butan-2-one + NADH + H+ => butan-2-ol + NAD+
Rhea:RHEA:64563 butan-2-ol + NAD+ <=> butan-2-one + NADH + H+
Rhea:RHEA:65293 6.4.1.6 butan-2-one + hydrogencarbonate + 2 ATP + 3 H2O => 3-oxopentanoate + 2 AMP + 4 phosphate + 4 H+
Rhea:RHEA:65294 6.4.1.6 3-oxopentanoate + 2 AMP + 4 phosphate + 4 H+ => butan-2-one + hydrogencarbonate + 2 ATP + 3 H2O
Rhea:RHEA:65295 6.4.1.6 butan-2-one + hydrogencarbonate + 2 ATP + 3 H2O <=> 3-oxopentanoate + 2 AMP + 4 phosphate + 4 H+
Rhea:RHEA:66441 butan-2-one + NADP+ => but-3-en-2-one + NADPH + H+
Rhea:RHEA:66442 but-3-en-2-one + NADPH + H+ => butan-2-one + NADP+
Rhea:RHEA:66443 butan-2-one + NADP+ <=> but-3-en-2-one + NADPH + H+
Rhea:RHEA:76848 (R)-sec-butylamine + NAD+ + H2O => butan-2-one + NH4+ + NADH + H+
Rhea:RHEA:76849 butan-2-one + NH4+ + NADH + H+ => (R)-sec-butylamine + NAD+ + H2O
Rhea:RHEA:76850 (R)-sec-butylamine + NAD+ + H2O <=> butan-2-one + NH4+ + NADH + H+
Rhea:RHEA:76852 (S)-sec-butylamine + NAD+ + H2O => butan-2-one + NH4+ + NADH + H+
View More
Organism Source

Taxonomy Source

  1. Acacia dealbata [ncbi taxid: 205042]
  2. Aloe africana [ncbi taxid: 1080010]
  3. Aloe ferox [ncbi taxid: 117798]
  4. Aloe spicata [ncbi taxid: 992642]
  5. Aloe vera [ncbi taxid: 34199]
  6. Amaranthus retroflexus [ncbi taxid: 124763]
  7. Camellia saluenensis [ncbi taxid: 319929]
  8. Daucus carota [ncbi taxid: 4039]
  9. Fragaria x ananassa [ncbi taxid: 3747]
  10. Homo sapiens [ncbi taxid: 9606]
  11. Capsicum annuum [ncbi taxid: 4072]
  12. Cnidium monieri [ncbi taxid: ]
  13. Cnidium monnieri [ncbi taxid: 94007]
  14. Hypericum japonicum [ncbi taxid: 282542]
  15. Torilis japonica [ncbi taxid: 49576]

Pathway Synthetic

pathway id name
BioCyc:META_PWY-6002 lotaustralin degradation
BioCyc:ARA_PWY-6786 detoxification of reactive carbonyls in chloroplasts
BioCyc:META_PWY-6604 superpathway of Clostridium acetobutylicum acidogenic and solventogenic fermentation
BioCyc:META_PWY-6588 pyruvate fermentation to acetone
BioCyc:META_PWY-6594 superpathway of Clostridium acetobutylicum solventogenic fermentation
BioCyc:META_PWY-6786 detoxification of reactive carbonyls in chloroplasts
BioCyc:THAPS_PWY-6002 lotaustralin degradation
BioCyc:META_PWY-7092 neolinustatin bioactivation
PlantCyc:ARA_PWY-6786 detoxification of reactive carbonyls in chloroplasts
PlantCyc:WHEATA_PWY-6786 detoxification of reactive carbonyls in chloroplasts
PlantCyc:WHEATD_PWY-6786 detoxification of reactive carbonyls in chloroplasts
PlantCyc:CACUMINATA_PWY-6786 detoxification of reactive carbonyls in chloroplasts
PlantCyc:CASTORBEAN_PWY-6002 lotaustralin degradation
PlantCyc:CCAPSULARIS_PWY-6786 detoxification of reactive carbonyls in chloroplasts
PlantCyc:RUBBERTREE_PWY-7092 neolinustatin bioactivation
PlantCyc:CHINESECABBAGE_PWY-6786 detoxification of reactive carbonyls in chloroplasts
PlantCyc:SPIDERFLOWER_PWY-6786 detoxification of reactive carbonyls in chloroplasts
PlantCyc:CLEMENTINE_PWY-6786 detoxification of reactive carbonyls in chloroplasts
PlantCyc:SWEETCHERRY_PWY-6786 detoxification of reactive carbonyls in chloroplasts
PlantCyc:COMMONBEAN_PWY-6002 lotaustralin degradation
View All Pathways