EC: 5.1.99.1

methylmalonyl-CoA epimerase (methylmalonyl-CoA 2-epimerase)

enzyme lambda metabolic reaction experiment
- [methylmalonyl-CoA epimerase(Enzyme) wildtype]

(R)_2_Methyl_3_oxopropanoyl_CoA -> (S)_2_Methyl_3_oxopropanoyl_CoA		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 10 mM Potassium phosphate, 150 mM NaCl, 0.1 mM CoCl2, 0.1 mg/ml BSA
PH: 7.5
Temperature: 30
- [Co2+]

(S)_2_Methyl_3_oxopropanoyl_CoA -> (R)_2_Methyl_3_oxopropanoyl_CoA		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 2.5 mM Potassium phosphate, 37.5 mM NaCl, 25 µg/ml BSA
PH: 7.5
Temperature: 30
- [Co2+]

(S)_2_Methyl_3_oxopropanoyl_CoA -> (R)_2_Methyl_3_oxopropanoyl_CoA		 (( (( (E * kcat) ) * M) ) / (Km + M)) buffer: 2.5 mM Potassium phosphate, 37.5 mM NaCl, 25 µg/ml BSA
PH: 7.5
Temperature: 30

Pathways

pathway id name
BioCyc:HUMAN_PWY-5328 superpathway of methionine degradation
BioCyc:META_PWY-5328 superpathway of L-methionine salvage and degradation
BioCyc:META_PWY-5130 2-oxobutanoate degradation I
BioCyc:MOUSE_PWY-5328 superpathway of methionine degradation
BioCyc:MOUSE_PWY3DJ-0 isoleucine degradation
BioCyc:HUMAN_PROPIONMET-PWY propionyl-CoA degradation
BioCyc:MOUSE_PROPIONMET-PWY methylmalonyl pathway
BioCyc:HUMAN_PWY-5130 2-oxobutanoate degradation
BioCyc:META_PROPIONMET-PWY propanoyl CoA degradation I
BioCyc:MOUSE_PWY3DJ-86 valine degradation
Reactome:R-DDI-77289 Mitochondrial Fatty Acid Beta-Oxidation
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-556833 Metabolism of lipids
Reactome:R-DDI-8978868 Fatty acid metabolism
Reactome:R-DDI-71032 Propionyl-CoA catabolism
Reactome:R-HSA-556833 Metabolism of lipids
Reactome:R-HSA-8978868 Fatty acid metabolism
Reactome:R-HSA-77289 Mitochondrial Fatty Acid Beta-Oxidation
Reactome:R-MMU-8978868 Fatty acid metabolism
Reactome:R-MMU-77289 Mitochondrial Fatty Acid Beta-Oxidation
Reactome:R-HSA-71032 Propionyl-CoA catabolism
Reactome:R-MMU-71032 Propionyl-CoA catabolism
Reactome:R-DDI-1430728 Metabolism
Reactome:R-DDI-556833 Metabolism of lipids
Reactome:R-HSA-1430728 Metabolism
PathBank:SMP0000016 Propanoate Metabolism
PathBank:SMP0087234 Valine, Leucine, and Isoleucine Degradation
PathBank:SMP0087262 Threonine and 2-Oxobutanoate Degradation
PathBank:SMP0000201 Methylmalonic Aciduria Due to Cobalamin-Related Disorders
PathBank:SMP0087248 Propanoate Metabolism
PathBank:SMP0000198 Malonic Aciduria
PathBank:SMP0000502 Malonyl-CoA Decarboxylase Deficiency