EC: 3.6.5.3

protein-synthesizing GTPase (GTP phosphohydrolase (mRNA-translation-assisting))

enzyme lambda metabolic reaction experiment

Pathways

pathway id name
PathBank:SMP0001006 Operon: Elongation Factor
Reactome:R-HSA-9633012 Response of EIF2AK4 (GCN2) to amino acid deficiency
Reactome:R-HSA-9648895 Response of EIF2AK1 (HRI) to heme deficiency
Reactome:R-HSA-9679506 SARS-CoV Infections
Reactome:R-HSA-9694516 SARS-CoV-2 Infection
Reactome:R-SPO-9840373 Cellular response to mitochondrial stress
Reactome:R-HSA-9711097 Cellular response to starvation
Reactome:R-BTA-9840373 Cellular response to mitochondrial stress
Reactome:R-DME-9840373 Cellular response to mitochondrial stress
Reactome:R-MMU-9840373 Cellular response to mitochondrial stress
Reactome:R-SCE-9840373 Cellular response to mitochondrial stress
Reactome:R-HSA-9754560 SARS-CoV-2 modulates autophagy
Reactome:R-HSA-9824446 Viral Infection Pathways
Reactome:R-DRE-9840373 Cellular response to mitochondrial stress
Reactome:R-DDI-9840373 Cellular response to mitochondrial stress
Reactome:R-HSA-9840373 Cellular response to mitochondrial stress
Reactome:R-RNO-9840373 Cellular response to mitochondrial stress
Reactome:R-HSA-9705683 SARS-CoV-2-host interactions
Reactome:R-HSA-9833482 PKR-mediated signaling
Reactome:R-MMU-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
Reactome:R-BTA-72695 Formation of the ternary complex, and subsequently, the 43S complex
Reactome:R-BTA-72731 Recycling of eIF2:GDP
Reactome:R-BTA-8953897 Cellular responses to stimuli
Reactome:R-BTA-2262752 Cellular responses to stress
Reactome:R-DRE-382551 Transport of small molecules
Reactome:R-DRE-392499 Metabolism of proteins
Reactome:R-DRE-72695 Formation of the ternary complex, and subsequently, the 43S complex
Reactome:R-DDI-72766 Translation
Reactome:R-DDI-72613 Eukaryotic Translation Initiation
Reactome:R-DDI-382551 Transport of small molecules
Reactome:R-DME-72737 Cap-dependent Translation Initiation
Reactome:R-DME-381119 Unfolded Protein Response (UPR)
Reactome:R-DME-381042 PERK regulates gene expression
Reactome:R-DME-382556 ABC-family proteins mediated transport
Reactome:R-HSA-392499 Metabolism of proteins
Reactome:R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex
Reactome:R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
Reactome:R-HSA-1643685 Disease
Reactome:R-HSA-1169410 Antiviral mechanism by IFN-stimulated genes
Reactome:R-MMU-72702 Ribosomal scanning and start codon recognition
Reactome:R-RNO-72766 Translation
Reactome:R-RNO-72613 Eukaryotic Translation Initiation
Reactome:R-RNO-72731 Recycling of eIF2:GDP
Reactome:R-RNO-382551 Transport of small molecules
Reactome:R-SCE-8953897 Cellular responses to stimuli
Reactome:R-SCE-382556 ABC-family proteins mediated transport
Reactome:R-SCE-72737 Cap-dependent Translation Initiation
Reactome:R-SCE-72702 Ribosomal scanning and start codon recognition
Reactome:R-SPO-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
Reactome:R-BTA-72737 Cap-dependent Translation Initiation
Reactome:R-BTA-72702 Ribosomal scanning and start codon recognition
Reactome:R-DRE-8953897 Cellular responses to stimuli
Reactome:R-DRE-72702 Ribosomal scanning and start codon recognition
Reactome:R-DRE-381119 Unfolded Protein Response (UPR)
Reactome:R-DRE-381042 PERK regulates gene expression
Reactome:R-DDI-392499 Metabolism of proteins
Reactome:R-DDI-72695 Formation of the ternary complex, and subsequently, the 43S complex
Reactome:R-DDI-72731 Recycling of eIF2:GDP
Reactome:R-DDI-381119 Unfolded Protein Response (UPR)
Reactome:R-DDI-2262752 Cellular responses to stress
Reactome:R-DME-72613 Eukaryotic Translation Initiation
Reactome:R-DME-72731 Recycling of eIF2:GDP
Reactome:R-DME-8953897 Cellular responses to stimuli
Reactome:R-DME-382551 Transport of small molecules
Reactome:R-HSA-382556 ABC-family proteins mediated transport
Reactome:R-HSA-2262752 Cellular responses to stress
Reactome:R-HSA-72702 Ribosomal scanning and start codon recognition
Reactome:R-HSA-5368287 Mitochondrial translation
Reactome:R-HSA-913531 Interferon Signaling
Reactome:R-MMU-382556 ABC-family proteins mediated transport
Reactome:R-MMU-72737 Cap-dependent Translation Initiation
Reactome:R-RNO-392499 Metabolism of proteins
Reactome:R-RNO-72695 Formation of the ternary complex, and subsequently, the 43S complex
Reactome:R-RNO-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
Reactome:R-RNO-8953897 Cellular responses to stimuli
Reactome:R-RNO-2262752 Cellular responses to stress
Reactome:R-SCE-382551 Transport of small molecules
Reactome:R-SCE-72766 Translation
Reactome:R-SCE-72613 Eukaryotic Translation Initiation
Reactome:R-SPO-72737 Cap-dependent Translation Initiation
Reactome:R-SPO-72702 Ribosomal scanning and start codon recognition
Reactome:R-SPO-2262752 Cellular responses to stress
Reactome:R-BTA-392499 Metabolism of proteins
Reactome:R-BTA-381119 Unfolded Protein Response (UPR)
Reactome:R-BTA-381042 PERK regulates gene expression
Reactome:R-BTA-382551 Transport of small molecules
Reactome:R-DRE-2262752 Cellular responses to stress
Reactome:R-DRE-382556 ABC-family proteins mediated transport
Reactome:R-DRE-72766 Translation
Reactome:R-DRE-72613 Eukaryotic Translation Initiation
Reactome:R-DRE-72731 Recycling of eIF2:GDP
Reactome:R-DDI-72737 Cap-dependent Translation Initiation
Reactome:R-DDI-72702 Ribosomal scanning and start codon recognition
Reactome:R-DDI-8953897 Cellular responses to stimuli
Reactome:R-DDI-382556 ABC-family proteins mediated transport
Reactome:R-DME-392499 Metabolism of proteins
Reactome:R-DME-72702 Ribosomal scanning and start codon recognition
Reactome:R-DME-2262752 Cellular responses to stress
Reactome:R-HSA-72766 Translation
Reactome:R-HSA-72613 Eukaryotic Translation Initiation
Reactome:R-HSA-72731 Recycling of eIF2:GDP
Reactome:R-HSA-5389840 Mitochondrial translation elongation
Reactome:R-HSA-381119 Unfolded Protein Response (UPR)
Reactome:R-HSA-168256 Immune System
Reactome:R-MMU-392499 Metabolism of proteins
Reactome:R-MMU-72695 Formation of the ternary complex, and subsequently, the 43S complex
Reactome:R-MMU-72731 Recycling of eIF2:GDP
Reactome:R-RNO-72737 Cap-dependent Translation Initiation
Reactome:R-RNO-381119 Unfolded Protein Response (UPR)
Reactome:R-RNO-381042 PERK regulates gene expression
Reactome:R-RNO-382556 ABC-family proteins mediated transport
Reactome:R-SCE-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
Reactome:R-SPO-382551 Transport of small molecules
Reactome:R-SPO-392499 Metabolism of proteins
Reactome:R-SPO-72695 Formation of the ternary complex, and subsequently, the 43S complex
Reactome:R-SPO-72731 Recycling of eIF2:GDP
Reactome:R-SPO-8953897 Cellular responses to stimuli
Reactome:R-BTA-72766 Translation
Reactome:R-BTA-72613 Eukaryotic Translation Initiation
Reactome:R-BTA-382556 ABC-family proteins mediated transport
Reactome:R-DRE-72737 Cap-dependent Translation Initiation
Reactome:R-DDI-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
Reactome:R-DDI-381042 PERK regulates gene expression
Reactome:R-DME-72766 Translation
Reactome:R-DME-72695 Formation of the ternary complex, and subsequently, the 43S complex
Reactome:R-HSA-382551 Transport of small molecules
Reactome:R-HSA-8953897 Cellular responses to stimuli
Reactome:R-HSA-72737 Cap-dependent Translation Initiation
Reactome:R-HSA-381042 PERK regulates gene expression
Reactome:R-HSA-5663205 Infectious disease
Reactome:R-HSA-1280215 Cytokine Signaling in Immune system
Reactome:R-MMU-382551 Transport of small molecules
Reactome:R-MMU-8953897 Cellular responses to stimuli
Reactome:R-MMU-2262752 Cellular responses to stress
Reactome:R-MMU-72766 Translation
Reactome:R-MMU-72613 Eukaryotic Translation Initiation
Reactome:R-MMU-381119 Unfolded Protein Response (UPR)
Reactome:R-MMU-381042 PERK regulates gene expression
Reactome:R-RNO-72702 Ribosomal scanning and start codon recognition
Reactome:R-SCE-2262752 Cellular responses to stress
Reactome:R-SCE-392499 Metabolism of proteins
Reactome:R-SCE-72695 Formation of the ternary complex, and subsequently, the 43S complex
Reactome:R-SCE-72731 Recycling of eIF2:GDP
Reactome:R-SPO-382556 ABC-family proteins mediated transport
Reactome:R-SPO-72766 Translation
Reactome:R-SPO-72613 Eukaryotic Translation Initiation