EC: 3.6.1.5

apyrase (nucleoside triphosphate phosphohydrolase (nucleoside monophosphoate-forming))

enzyme lambda metabolic reaction experiment
uniprot:Q8K0L2 [Ca2+]

H2O + ADP -> Phosphate + AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM MES
PH: 6.4
Temperature: 37
uniprot:Q8K0L2 [Ca2+]

ATP + H2O -> Phosphate + ADP		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM MES
PH: 6.4
Temperature: 37
uniprot:Q8K0L2 [Ca2+]

UDP + H2O -> UMP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM MES
PH: 6.4
Temperature: 37
uniprot:Q8K0L2 [Ca2+]

H2O + UTP -> UDP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM MES
PH: 6.4
Temperature: 37
uniprot:E0D877 [Ca2+]

2 H2O + ATP -> AMP + 2 Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris, 150 mM NaCl, 2.5 mM DTT, 0.05 % Tween20, 0.25 ng/µl BSA
PH: 7.5
Temperature: 37
uniprot:P22413 [apyrase(Enzyme) wildtype NPP1]

2 H2O + PSB_170621A -> 2 Phosphate + PSB_170621B		 (( (( (kcat * E) ) * S) ) / (S + Km)) buffer: 10 mM CHES, 1 mM MgCl2, 2 mM CaCl2
PH: 9
Temperature: 37
uniprot:O75355 [apyrase(Enzyme) wildtype NTPDase3]

PSB_170621A + 2 H2O -> 2 Phosphate + PSB_170621B		 (( (( (kcat * E) ) * S) ) / (S + Km)) buffer: 10 mM HEPES, 1 mM MgCl2, 2 mM CaCl2
PH: 7.4
Temperature: 37
uniprot:Q5MY95 [apyrase(Enzyme) wildtype NTPDase8]

PSB_170621A + 2 H2O -> 2 Phosphate + PSB_170621B		 (( (( (kcat * E) ) * S) ) / (S + Km)) buffer: 10 mM HEPES, 1 mM MgCl2, 2 mM CaCl2
PH: 7.4
Temperature: 37
uniprot:Q9Y5L3 [apyrase(Enzyme) wildtype NTPDase2]

PSB_170621A + 2 H2O -> PSB_170621B + 2 Phosphate		 (( (( (kcat * E) ) * S) ) / (S + Km)) buffer: 10 mM HEPES, 1 mM MgCl2, 2 mM CaCl2
PH: 7.4
Temperature: 37
uniprot:P05186 [apyrase(Enzyme) wildtype TNAP]

2 H2O + PSB_170621A -> PSB_170621B + 2 Phosphate		 (( (( (kcat * E) ) * S) ) / (S + Km)) buffer: 10 mM CHES, 1 mM MgCl2, 2 mM CaCl2
PH: 9
Temperature: 37
uniprot:O14638 [apyrase(Enzyme) wildtype NPP3]

2 H2O + PSB_170621A -> 2 Phosphate + PSB_170621B		 (( (( (kcat * E) ) * S) ) / (S + Km)) buffer: 10 mM CHES, 1 mM MgCl2, 2 mM CaCl2
PH: 9
Temperature: 37
uniprot:P49961 [apyrase(Enzyme) wildtype NTPDase1]

ATP + 2 H2O -> AMP + 2 Phosphate		 (( (( (kcat * E) ) * S) ) / (S + Km)) buffer: 10 mM HEPES, 1 mM MgCl2, 2 mM CaCl2
PH: 7.4
Temperature: 37
uniprot:P49961 [apyrase(Enzyme) wildtype NTPDase1]

PSB_170621A + 2 H2O -> 2 Phosphate + PSB_170621B		 (( (( (kcat * E) ) * S) ) / (S + Km)) buffer: 10 mM HEPES, 1 mM MgCl2, 2 mM CaCl2
PH: 7.4
Temperature: 37
uniprot:P97687 [apyrase(Enzyme) wildtype NTPDase1]

PSB_170621A + 2 H2O -> PSB_170621B + 2 Phosphate		 (( (( (kcat * E) ) * S) ) / (S + Km)) buffer: 10 mM HEPES, 1 mM MgCl2, 2 mM CaCl2
PH: 7.4
Temperature: 37
uniprot:P55772 [apyrase(Enzyme) wildtype NTPDase1]

PSB_170621A + 2 H2O -> PSB_170621B + 2 Phosphate		 (( (( (kcat * E) ) * S) ) / (S + Km)) buffer: 10 mM HEPES, 1 mM MgCl2, 2 mM CaCl2
PH: 7.4
Temperature: 37
uniprot:Q5DRK1 [Ca2+]

ADP + H2O -> Phosphate + AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:O75355 [Ca2+]

ADP + H2O -> AMP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:Q5DRK1 [Ca2+]

H2O + ATP -> ADP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:O75355 [Ca2+]

H2O + ATP -> ADP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:P55772 [Ca2+]

ATP + 2 H2O -> 2 Phosphate + AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:Q5DRK1 [Ca2+]

H2O + UDP -> Phosphate + UMP		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:O75355 [Ca2+]

UDP + H2O -> Phosphate + UMP		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:Q5DRK1 [Ca2+]

H2O + UTP -> Phosphate + UDP		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:O75355 [Ca2+]

H2O + UTP -> UDP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:P49961 [Ca2+]

ADP + H2O -> AMP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:Q9Y5L3 [Ca2+]

H2O + ATP -> Phosphate + ADP		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:P49961 [Ca2+]

2 H2O + ATP -> AMP + 2 Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:P49961 [Ca2+]

UDP + H2O -> Phosphate + UMP		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:Q9Y5L3 [Ca2+]

H2O + UTP -> UDP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:P49961 [Ca2+]

H2O + UTP -> Phosphate + UDP		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:P55772 [Ca2+]

H2O + ADP -> AMP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:O55026 [Ca2+]

H2O + ATP -> ADP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:P55772 [Ca2+]

UDP + H2O -> Phosphate + UMP		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:P55772 [Ca2+]

H2O + UTP -> UDP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:O55026 [Ca2+]

UTP + H2O -> Phosphate + UDP		 (( (Vmax * S) ) / (Km + S)) buffer: 80 mM Tris
PH: 7.4
Temperature: 37
uniprot:Q8BFW6 [apyrase(Enzyme) wildtype]

H2O + ADP -> Phosphate + AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM Tris, 5 mM CaCl2
PH: 7.4
Temperature: 37
uniprot:Q8BFW6 [apyrase(Enzyme) wildtype]

H2O + ATP -> Phosphate + ADP		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM Tris, 5 mM CaCl2
PH: 7.4
Temperature: 37
uniprot:Q9MYU4 [apyrase(Enzyme) wildtype NTPDase1]

2 H2O + ATP -> 2 Phosphate + AMP		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Hepes/OH, 3 mM CaCl2, 8 mM EGTA, 2 mM ouabain
PH: 7.6
Temperature: 37
uniprot:Q8BFW6 [apyrase(Enzyme) wildtype]

H2O + UDP -> Phosphate + UMP		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM Tris, 5 mM CaCl2
PH: 7.4
Temperature: 37
uniprot:Q8BFW6 [apyrase(Enzyme) wildtype]

H2O + UTP -> Phosphate + UDP		 (( (Vmax * S) ) / (Km + S)) buffer: 100 mM Tris, 5 mM CaCl2
PH: 7.4
Temperature: 37
uniprot:Q9MYU4 [apyrase(Enzyme) wildtype NTPDase1]

H2O + ADP -> Phosphate + AMP		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Hepes/OH, 3 mM CaCl2, 8 mM EGTA, 2 mM ouabain
PH: 7.6
Temperature: 37
- [apyrase(Enzyme) wildtype NTPDase2]

ATP + H2O -> Phosphate + ADP		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Hepes/OH, 3 mM CaCl2, 8 mM EGTA, 2 mM ouabain
PH: 7.6
Temperature: 37
uniprot:Q9Y5L3 [Mg2+]

ATP + 2 H2O -> AMP + 2 Phosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 25 mM Tris-Cl
PH: 7.5
Temperature: 37
- [apyrase(Enzyme) wildtype]

H2O + ADP -> Phosphate + AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris, 50 mM imidazole, 1.5 mM CaCl2
PH: 7.4
Temperature: 37
uniprot:Q9Y5L3 [apyrase(Enzyme) wildtype]

H2O + ADP -> AMP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 20 mM Hepes, 125 mM NaCl, 5.2 mM KCl, 2 mM CaCl2, 1.2 mM MgCl2, 5 mM D-glucose
PH: 7.4
Temperature: 37
- [apyrase(Enzyme) wildtype NTPDase2]

ADP + H2O -> AMP + Phosphate		 (( (( (E * kcat) ) * S) ) / (Km + S)) buffer: 50 mM Hepes/OH, 3 mM CaCl2, 8 mM EGTA, 2 mM ouabain
PH: 7.6
Temperature: 37
- [apyrase(Enzyme) wildtype]

ATP + 2 H2O -> AMP + 2 Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris, 50 mM imidazole, 1.5 mM CaCl2
PH: 7.4
Temperature: 37
uniprot:Q9Y5L3 [apyrase(Enzyme) wildtype]

2 H2O + ATP -> AMP + 2 Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 20 mM Hepes, 125 mM NaCl, 5.2 mM KCl, 2 mM CaCl2, 1.2 mM MgCl2, 5 mM D-glucose
PH: 7.4
Temperature: 37
uniprot:O75355 [apyrase(Enzyme) wildtype]

H2O + ADP -> Phosphate + AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 20 mM MOPS/NaOH, 1 mM EGTA
PH: 7.4
Temperature: 37
uniprot:O75355 [apyrase(Enzyme) mutant G64A]

ADP + H2O -> AMP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 20 mM MOPS/NaOH, 1 mM EGTA
PH: 7.4
Temperature: 37
uniprot:O75355 [apyrase(Enzyme) mutant D219A]

ATP + 2 H2O -> AMP + 2 Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 20 mM MOPS/NaOH, 1 mM EGTA
PH: 7.4
Temperature: 37
uniprot:O75355 [apyrase(Enzyme) mutant D219E]

2 H2O + ATP -> 2 Phosphate + AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 20 mM MOPS/NaOH, 1 mM EGTA
PH: 7.4
Temperature: 37
uniprot:O75355 [apyrase(Enzyme) mutant A511STOP]

ATP + 2 H2O -> 2 Phosphate + AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 20 mM MOPS/NaOH, 1 mM EGTA
PH: 7.4
Temperature: 37
uniprot:O75355 [apyrase(Enzyme) mutant D62A]

ATP + 2 H2O -> 2 Phosphate + AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 20 mM MOPS/NaOH, 1 mM EGTA
PH: 7.4
Temperature: 37
uniprot:O75355 [apyrase(Enzyme) wildtype]

2 H2O + ATP -> 2 Phosphate + AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 20 mM MOPS/NaOH, 1 mM EGTA
PH: 7.4
Temperature: 37
uniprot:O75355 [apyrase(Enzyme) mutant D219N]

ATP + 2 H2O -> AMP + 2 Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 20 mM MOPS/NaOH, 1 mM EGTA
PH: 7.4
Temperature: 37
uniprot:O75355 [apyrase(Enzyme) mutant G64A]

ATP + 2 H2O -> 2 Phosphate + AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 20 mM MOPS/NaOH, 1 mM EGTA
PH: 7.4
Temperature: 37
uniprot:O75355 [apyrase(Enzyme) mutant D219E]

ADP + H2O -> AMP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 20 mM MOPS/NaOH, 1 mM EGTA
PH: 7.4
Temperature: 37
uniprot:O75355 [apyrase(Enzyme) mutant A511STOP]

ADP + H2O -> AMP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 20 mM MOPS/NaOH, 1 mM EGTA
PH: 7.4
Temperature: 37
uniprot:O18956 [Ca2+]

ADP + H2O -> AMP + Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-OH, 50 mM imidazole
PH: 7.5
Temperature: 37
uniprot:O18956 [Ca2+]

ATP + 2 H2O -> AMP + 2 Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-OH, 50 mM imidazole
PH: 7.5
Temperature: 37
uniprot:O18956 [Ca2+]

2 H2O + 2_Methylthio_ATP -> 2 Phosphate + 2_Methylthio_AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-OH, 50 mM imidazole
PH: 7.5
Temperature: 37
uniprot:O18956 [Ca2+]

2 H2O + 8_Bromoadenosine_5'_triphosphate -> 2 Phosphate + 8_Bromo_AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-OH, 50 mM imidazole
PH: 7.5
Temperature: 37
uniprot:O18956 [Ca2+]

2_Chloro_ATP + 2 H2O -> 2_Chloro_AMP + 2 Phosphate		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris-OH, 50 mM imidazole
PH: 7.5
Temperature: 37
uniprot:P49961 [Mg2+]

H2O + ADP -> Phosphate + AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris/HCl
PH: 8
Temperature: 30
uniprot:P49961 [Mg2+]

2 H2O + ATP -> 2 Phosphate + AMP		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Tris/HCl
PH: 8
Temperature: 30
uniprot:P02829 [apyrase(Enzyme) wildtype]

H2O + ATP -> ADP + Phosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 25 mM HEPES, 5 mM MgCl2, 400 mM KCl, 0.03% Tween 20, 10% glycerol, 200 μM NADH, 3 mM phosphoenol pyruvate, 15.7 U pyruvate kinase, 24.5 U lactate dehydrogenase
PH: 7.5
Temperature: 36
uniprot:Q9STX5 [apyrase(Enzyme) wildtype]

ATP + H2O -> ADP + Phosphate		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 25 mM HEPES, 5 mM MgCl2, 400 mM KCl, 0.03% Tween 20, 10% glycerol, 200 μM NADH, 3 mM phosphoenol pyruvate, 15.7 U pyruvate kinase, 24.5 U lactate dehydrogenase
PH: 7.5
Temperature: 36
uniprot:Q9STX5 [apyrase(Enzyme) mutant delta22 (488-509 deleted)]

ATP + H2O -> Phosphate + ADP		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 25 mM HEPES, 5 mM MgCl2, 400 mM KCl, 0.03% Tween 20, 10% glycerol, 200 μM NADH, 3 mM phosphoenol pyruvate, 15.7 U pyruvate kinase, 24.5 U lactate dehydrogenase
PH: 7.5
Temperature: 36
uniprot:P41148 [apyrase(Enzyme) wildtype]

ATP + H2O -> Phosphate + ADP		 (( (( (kcat * E) ) * S) ) / (Km + S)) buffer: 25 mM HEPES, 5 mM MgCl2, 400 mM KCl, 0.03% Tween 20, 10% glycerol, 200 μM NADH, 3 mM phosphoenol pyruvate, 15.7 U pyruvate kinase, 24.5 U lactate dehydrogenase
PH: 7.5
Temperature: 36
uniprot:Q9MYU4 [apyrase(Enzyme) wildtype]

ADP + H2O -> Phosphate + AMP		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM 4-(2-hydroxyethyl)-1-piperazine- 2-hydroxypropanesulfonic acid, 1 mM CaCl2
PH: 8
Temperature: 37
uniprot:Q9MYU4 [apyrase(Enzyme) wildtype]

ATP + H2O -> ADP + Phosphate		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM 4-(2-hydroxyethyl)-1-piperazine- 2-hydroxypropanesulfonic acid, 1 mM CaCl2
PH: 8
Temperature: 37

Pathways

pathway id name
BioCyc:HUMAN_PWY-7185 UTP and CTP dephosphorylation I
BioCyc:META_PWY-7177 UTP and CTP dephosphorylation II
BioCyc:META_PWY-7185 UTP and CTP dephosphorylation I
BioCyc:YEAST_PWY-7177 UTP and CTP dephosphorylation II
Reactome:R-HSA-9660826 Purinergic signaling in leishmaniasis infection
Reactome:R-HSA-9664424 Cell recruitment (pro-inflammatory response)
Reactome:R-HSA-9658195 Leishmania infection
Reactome:R-HSA-9824443 Parasitic Infection Pathways
Reactome:R-HSA-1643685 Disease
Reactome:R-MMU-1430728 Metabolism
Reactome:R-SPO-1430728 Metabolism
Reactome:R-SPO-15869 Nucleotide metabolism
Reactome:R-SPO-8956319 Nucleotide catabolism
Reactome:R-SPO-8850843 Phosphate bond hydrolysis by NTPDase proteins
Reactome:R-SCE-1430728 Metabolism
Reactome:R-RNO-1430728 Metabolism
Reactome:R-SCE-15869 Nucleotide metabolism
Reactome:R-SCE-8956319 Nucleotide catabolism
Reactome:R-SCE-8850843 Phosphate bond hydrolysis by NTPDase proteins
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-15869 Nucleotide metabolism
Reactome:R-HSA-8956319 Nucleotide catabolism
Reactome:R-HSA-8850843 Phosphate bond hydrolysis by NTPDase proteins
Reactome:R-HSA-5663205 Infectious disease
Reactome:R-MMU-15869 Nucleotide metabolism
Reactome:R-MMU-8956319 Nucleotide catabolism
Reactome:R-MMU-8850843 Phosphate bond hydrolysis by NTPDase proteins
Reactome:R-RNO-15869 Nucleotide metabolism
Reactome:R-RNO-8956319 Nucleotide catabolism
Reactome:R-RNO-8850843 Phosphate bond hydrolysis by NTPDase proteins
WikiPathways:WP5078 T cell modulation in pancreatic cancer
PathBank:SMP0120670 Adenylosuccinate Lyase Deficiency
PathBank:SMP0000167 Adenylosuccinate Lyase Deficiency
PathBank:SMP0000220 Xanthine Dehydrogenase Deficiency (Xanthinuria)
PathBank:SMP0000512 Xanthinuria Type I
PathBank:SMP0000536 Mitochondrial DNA Depletion Syndrome-3
PathBank:SMP0120669 Adenosine Deaminase Deficiency
PathBank:SMP0120673 AICA-Ribosiduria
PathBank:SMP0120709 Gout or Kelley-Seegmiller Syndrome
PathBank:SMP0120717 Xanthine Dehydrogenase Deficiency (Xanthinuria)
PathBank:SMP0120797 Xanthinuria Type II
PathBank:SMP0120821 Myoadenylate Deaminase Deficiency
PathBank:SMP0000050 Purine Metabolism
PathBank:SMP0000144 Adenosine Deaminase Deficiency
PathBank:SMP0000203 Molybdenum Cofactor Deficiency
PathBank:SMP0000428 Mercaptopurine Action Pathway
PathBank:SMP0000535 Adenine Phosphoribosyltransferase Deficiency (APRT)
PathBank:SMP0120728 Lesch-Nyhan Syndrome (LNS)
PathBank:SMP0120752 Molybdenum Cofactor Deficiency
PathBank:SMP0120756 Purine Nucleoside Phosphorylase Deficiency
PathBank:SMP0120796 Xanthinuria Type I
PathBank:SMP0120820 Mitochondrial DNA Depletion Syndrome
PathBank:SMP0000365 Gout or Kelley-Seegmiller Syndrome
PathBank:SMP0000210 Purine Nucleoside Phosphorylase Deficiency
PathBank:SMP0000430 Thioguanine Action Pathway
PathBank:SMP0000513 Xanthinuria Type II
PathBank:SMP0000537 Myoadenylate Deaminase Deficiency
PathBank:SMP0087332 Purine Metabolism
PathBank:SMP0120819 Adenine Phosphoribosyltransferase Deficiency (APRT)
PathBank:SMP0000364 Lesch-Nyhan Syndrome (LNS)
PathBank:SMP0000168 AICA-Ribosiduria
PathBank:SMP0000427 Azathioprine Action Pathway
PathBank:SMP0087239 Purine Metabolism