EC: 3.5.1.25

N-acetylglucosamine-6-phosphate deacetylase (N-acetyl-D-glucosamine-6-phosphate amidohydrolase)

enzyme lambda metabolic reaction experiment
uniprot:Q5BJY6 [N-acetylglucosamine-6-phosphate deacetylase(Enzyme) wildtype]

N_Acetyl_D_glucosamine_6_phosphate + H2O -> D_Glucosamine_6_phosphate + Acetate
(( (Vmax * A) ) / (Km + A)) buffer: 0.01 M Tris-HCl
PH: 8
Temperature: 37
uniprot:P0AF18 [N-acetylglucosamine-6-phosphate deacetylase(Enzyme) wildtype]

N_Acetyl_D_glucosamine_6_phosphate + H2O -> D_Glucosamine_6_phosphate + Acetate
(( (Vmax * A) ) / (Km + A)) buffer: 20 mM Sodium phosphate, 0.2 mM NADP, 50 µg/ml Glucosamine 6-phosphate deaminase, 8 units/ml Glucose phosphate isomerase, 3 units/ml Glucose 6-phosphate dehydrogenase
PH: 8
Temperature: 37
uniprot:O34450 [N-acetylglucosamine-6-phosphate deacetylase(Enzyme) wildtype]

N_Acetyl_D_glucosamine_6_phosphate + H2O -> D_Glucosamine_6_phosphate + Acetate
(( (Vmax * A) ) / (Km + A)) buffer: 100 mM Tris-HCl
PH: 8.5
Temperature: 36

Pathways

pathway id name
BioCyc:HUMAN_PWY-6517 N-acetylglucosamine degradation II
BioCyc:META_PWY-6906 chitin derivatives degradation
BioCyc:META_P441-PWY superpathway of N-acetylneuraminate degradation
BioCyc:META_PWY-7077 N-acetyl-D-galactosamine degradation
BioCyc:ECOO157_GLUAMCAT-PWY N-acetylglucosamine degradation I
BioCyc:ECOO157_P441-PWY superpathway of N-acetylneuraminate degradation
BioCyc:META_GLUAMCAT-PWY N-acetylglucosamine degradation I
BioCyc:META_PWY0-1261 anhydromuropeptides recycling I
BioCyc:ECO_GLUAMCAT-PWY N-acetylglucosamine degradation I
BioCyc:MOUSE_GLCMANNANAUT-PWY superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation
BioCyc:MOUSE_PWY-6517 N-acetylglucosamine degradation II
BioCyc:BSUB_GLUAMCAT-PWY N-acetylglucosamine degradation I
BioCyc:ECOL316407_GLCMANNANAUT-PWY superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation
BioCyc:ECOL316407_PWY0-1261 anhydromuropeptides recycling
BioCyc:META_PWY-6517 N-acetylglucosamine degradation II
BioCyc:META_GLCMANNANAUT-PWY superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation
BioCyc:ECO_GLCMANNANAUT-PWY superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation
BioCyc:VCHO_P441-PWY superpathway of N-acetylneuraminate degradation
BioCyc:ECOO157_PWY-7395 D-galactosamine and N-acetyl-D-galactosamine degradation
BioCyc:ECOO157_PWY0-1261 anhydromuropeptides recycling
BioCyc:ECOO157_GLCMANNANAUT-PWY superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation
BioCyc:ECOL316407_GLUAMCAT-PWY N-acetylglucosamine degradation I
BioCyc:HUMAN_GLUAMCAT-PWY N-acetylglucosamine degradation I
BioCyc:ECO_PWY0-1261 anhydromuropeptides recycling I
BioCyc:VCHO_GLCMANNANAUT-PWY superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation
BioCyc:VCHO_GLUAMCAT-PWY N-acetylglucosamine degradation I
BioCyc:MOUSE_GLUAMCAT-PWY N-acetylglucosamine degradation I
PathBank:SMP0000905 Amino Sugar and Nucleotide Sugar Metabolism I
PathBank:SMP0000906 Amino Sugar and Nucleotide Sugar Metabolism II
PathBank:SMP0000914 Amino Sugar and Nucleotide Sugar Metabolism III
PathBank:SMP0002044 N-Acetylneuraminate, N-Acetylmannosamine, and N-Acetylglucosamine Degradation
PathBank:SMP0002076 1,6-Anhydro-N-acetylmuramic Acid Recycling
Reactome:R-BTA-597592 Post-translational protein modification
Reactome:R-CEL-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-DRE-392499 Metabolism of proteins
Reactome:R-DRE-446219 Synthesis of substrates in N-glycan biosythesis
Reactome:R-DME-597592 Post-translational protein modification
Reactome:R-DME-446219 Synthesis of substrates in N-glycan biosythesis
Reactome:R-HSA-392499 Metabolism of proteins
Reactome:R-HSA-597592 Post-translational protein modification
Reactome:R-MMU-446219 Synthesis of substrates in N-glycan biosythesis
Reactome:R-RNO-597592 Post-translational protein modification
Reactome:R-BTA-446219 Synthesis of substrates in N-glycan biosythesis
Reactome:R-CEL-392499 Metabolism of proteins
Reactome:R-CEL-597592 Post-translational protein modification
Reactome:R-CEL-446203 Asparagine N-linked glycosylation
Reactome:R-CEL-446210 Synthesis of UDP-N-acetyl-glucosamine
Reactome:R-DRE-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-DME-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-HSA-446219 Synthesis of substrates in N-glycan biosythesis
Reactome:R-MMU-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-RNO-392499 Metabolism of proteins
Reactome:R-RNO-446219 Synthesis of substrates in N-glycan biosythesis
Reactome:R-BTA-392499 Metabolism of proteins
Reactome:R-BTA-446203 Asparagine N-linked glycosylation
Reactome:R-BTA-446210 Synthesis of UDP-N-acetyl-glucosamine
Reactome:R-CEL-446219 Synthesis of substrates in N-glycan biosythesis
Reactome:R-DME-392499 Metabolism of proteins
Reactome:R-HSA-446203 Asparagine N-linked glycosylation
Reactome:R-HSA-446210 Synthesis of UDP-N-acetyl-glucosamine
Reactome:R-MMU-392499 Metabolism of proteins
Reactome:R-MMU-597592 Post-translational protein modification
Reactome:R-RNO-446203 Asparagine N-linked glycosylation
Reactome:R-RNO-446210 Synthesis of UDP-N-acetyl-glucosamine
Reactome:R-BTA-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-DRE-597592 Post-translational protein modification
Reactome:R-DRE-446203 Asparagine N-linked glycosylation
Reactome:R-DRE-446210 Synthesis of UDP-N-acetyl-glucosamine
Reactome:R-DME-446203 Asparagine N-linked glycosylation
Reactome:R-DME-446210 Synthesis of UDP-N-acetyl-glucosamine
Reactome:R-HSA-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Reactome:R-MMU-446203 Asparagine N-linked glycosylation
Reactome:R-MMU-446210 Synthesis of UDP-N-acetyl-glucosamine
Reactome:R-RNO-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
PathBank:SMP0120818 G(M2)-Gangliosidosis: Variant B, Tay-Sachs Disease
PathBank:SMP0120524 Salla Disease/Infantile Sialic Acid Storage Disease
PathBank:SMP0000240 Salla Disease/Infantile Sialic Acid Storage Disease
PathBank:SMP0087374 Amino Sugar Metabolism
PathBank:SMP0120737 Sialuria or French Type Sialuria
PathBank:SMP0120765 Tay-Sachs Disease
PathBank:SMP0000045 Amino Sugar Metabolism
PathBank:SMP0000216 Sialuria or French Type Sialuria
PathBank:SMP0087281 Amino Sugar Metabolism
PathBank:SMP0120744 Salla Disease/Infantile Sialic Acid Storage Disease
PathBank:SMP0120517 Sialuria or French Type Sialuria
PathBank:SMP0120545 Tay-Sachs Disease
PathBank:SMP0000390 Tay-Sachs Disease
PathBank:SMP0087175 Amino Sugar Metabolism
PathBank:SMP0120599 G(M2)-Gangliosidosis: Variant B, Tay-Sachs Disease
PathBank:SMP0000534 G(M2)-Gangliosidosis: Variant B, Tay-Sachs Disease
PathBank:SMP0063580 Amino Sugar Metabolism