EC: 3.1.1.64

retinoid isomerohydrolase (all-trans-retinyl ester acylhydrolase, 11-cis retinol forming)

enzyme lambda metabolic reaction experiment
uniprot:Q28175 [all-trans-retinyl-palmitate hydrolase(Enzyme) wildtype]

H2O + All_trans_Retinyl_palmitate -> Palmitate + 11_cis_Retinol		 (( (Vmax * A) ) / (Km + A)) buffer: 25 mM HEPES, 100 mM NaCl, 2 mM CaCl2, 2 mM MgCl2, 20 mM leupeptin, 6 mM sodium cholate, 5% BSA
PH: 7.5
Temperature: 37

Pathways

pathway id name
BioCyc:META_PWY-6861 the visual cycle I (vertebrates)
BioCyc:HUMAN_PWY-6861 the visual cycle I (vertebrates)
Reactome:R-HSA-9709957 Sensory Perception
Reactome:R-MMU-9709957 Sensory Perception
Reactome:R-DRE-9709957 Sensory Perception
Reactome:R-RNO-9709957 Sensory Perception
Reactome:R-MMU-2453902 The canonical retinoid cycle in rods (twilight vision)
Reactome:R-DRE-2453902 The canonical retinoid cycle in rods (twilight vision)
Reactome:R-MMU-2187338 Visual phototransduction
Reactome:R-DRE-2187338 Visual phototransduction
Reactome:R-HSA-2187338 Visual phototransduction
Reactome:R-RNO-2187338 Visual phototransduction
Reactome:R-HSA-2453902 The canonical retinoid cycle in rods (twilight vision)
Reactome:R-RNO-2453902 The canonical retinoid cycle in rods (twilight vision)
WikiPathways:WP5188 Retinol metabolism
PathBank:SMP0000074 Retinol Metabolism
PathBank:SMP0000336 Vitamin A Deficiency