EC: 2.6.1.57

aromatic-amino-acid transaminase (aromatic-amino-acid:2-oxoglutarate aminotransferase)

enzyme lambda metabolic reaction experiment
uniprot:O85746 [Pyridoxal phosphate]

L_Phenylalanine + 4_Methylthio_2_oxobutanoate -> L_Methionine + Phenylpyruvate		 (( (Vmax * S) ) / (Km + S)) buffer: 10 mM phosphate
PH: 7.4
Temperature: 37
uniprot:O85746 [Pyridoxal phosphate]

L_Tryptophan + 4_Methylthio_2_oxobutanoate -> L_Methionine + Indolepyruvate		 (( (Vmax * S) ) / (Km + S)) buffer: 10 mM phosphate
PH: 7.4
Temperature: 37

Pathways

pathway id name
BioCyc:META_PWY-6628 superpathway of L-phenylalanine biosynthesis
BioCyc:META_PHESYN L-phenylalanine biosynthesis I
BioCyc:META_TYRFUMCAT-PWY L-tyrosine degradation I
BioCyc:META_ALL-CHORISMATE-PWY superpathway of chorismate metabolism
BioCyc:ECO_LEUSYN-PWY L-leucine biosynthesis
BioCyc:ECO_COMPLETE-ARO-PWY superpathway of aromatic amino acid biosynthesis
BioCyc:MTBCDC1551_HISTSYN-PWY L-histidine biosynthesis
BioCyc:ECOL316407_ALL-CHORISMATE-PWY superpathway of chorismate metabolism
BioCyc:CORYNE_PHESYN L-phenylalanine biosynthesis I
BioCyc:META_LYSINE-AMINOAD-PWY L-lysine biosynthesis IV
BioCyc:META_PWY-5754 4-hydroxybenzoate biosynthesis I (eukaryotes)
BioCyc:META_PWY-5079 L-phenylalanine degradation III
BioCyc:META_LEUSYN-PWY L-leucine biosynthesis
BioCyc:META_PWY-6630 superpathway of L-tyrosine biosynthesis
BioCyc:ECO_BRANCHED-CHAIN-AA-SYN-PWY superpathway of branched chain amino acid biosynthesis
BioCyc:YEAST_PWY-5886 4-hydroxyphenylpyruvate biosynthesis
BioCyc:YEAST_PWY-5082 L-methionine degradation III
BioCyc:YEAST_PWY3O-4108 tyrosine degradation
BioCyc:YEAST_LYSINE-AMINOAD-PWY L-lysine biosynthesis IV
BioCyc:ECOL316407_COMPLETE-ARO-PWY superpathway of phenylalanine, tyrosine, and tryptophan biosynthesis
BioCyc:META_TYRSYN L-tyrosine biosynthesis I
BioCyc:META_PWY-5327 superpathway of L-lysine degradation
BioCyc:META_PWY3O-4108 L-tyrosine degradation III
BioCyc:META_BRANCHED-CHAIN-AA-SYN-PWY superpathway of branched chain amino acid biosynthesis
BioCyc:META_COMPLETE-ARO-PWY superpathway of aromatic amino acid biosynthesis
BioCyc:YEAST_COMPLETE-ARO-YEAST-PWY superpathway of phenylalanine, tyrosine and tryptophan biosynthesis
BioCyc:YEAST_PWY3O-4120 tyrosine biosynthesis
BioCyc:YEAST_PWY-5081 tryptophan degradation VIII (to tryptophol)
BioCyc:YEAST_PWY-5079 phenylalanine degradation
BioCyc:MTBH37RV_HISTSYN-PWY L-histidine biosynthesis
BioCyc:ECOL316407_BRANCHED-CHAIN-AA-SYN-PWY superpathway of leucine, valine, and isoleucine biosynthesis
BioCyc:CORYNE_COMPLETE-ARO-PWY superpathway of aromatic amino acid biosynthesis
BioCyc:CORYNE_PWY-5886 4-hydroxyphenylpyruvate biosynthesis
BioCyc:CORYNE_PWY-6628 superpathway of L-phenylalanine biosynthesis
BioCyc:META_PWY-5081 L-tryptophan degradation VIII (to tryptophol)
BioCyc:META_ANAPHENOXI-PWY L-phenylalanine degradation II (anaerobic)
BioCyc:META_PWY-5082 L-methionine degradation III
BioCyc:META_PWY-5886 4-hydroxyphenylpyruvate biosynthesis
BioCyc:ECO_TYRSYN L-tyrosine biosynthesis I
BioCyc:ECO_ALL-CHORISMATE-PWY superpathway of chorismate metabolism
BioCyc:ECO_PHESYN L-phenylalanine biosynthesis I
BioCyc:ECOL316407_TYRSYN tyrosine biosynthesis I
BioCyc:ECOL316407_LEU-DEG2-PWY leucine degradation I
BioCyc:ECOL316407_PHESYN phenylalanine biosynthesis I
BioCyc:ECOL316407_LEUSYN-PWY leucine biosynthesis
BioCyc:CORYNE_PWY-6630 superpathway of L-tyrosine biosynthesis
BioCyc:CORYNE_TYRSYN L-tyrosine biosynthesis I
PathBank:SMP0000826 Tyrosine Biosynthesis
PathBank:SMP0000831 Leucine Biosynthesis
PathBank:SMP0000938 Phenylalanine Metabolism
PathBank:SMP0000996 Secondary Metabolites: Leucine Biosynthesis
Reactome:R-DDI-71291 Amino acid and derivative metabolism
Reactome:R-DDI-71240 Tryptophan catabolism
Reactome:R-DDI-1430728 Metabolism
Reactome:R-DDI-71064 Lysine catabolism
PathBank:SMP0002353 Tryptophan Metabolism
PathBank:SMP0002352 Tyrosine Metabolism
PathBank:SMP0002310 Methionine Metabolism and Salvage
PathBank:SMP0002349 Phenylalanine Metabolism