EC: 2.4.1.122

N-acetylgalactosaminide beta-1,3-galactosyltransferase (UDP-alpha-D-galactose:N-acetyl-alpha-D-galactosaminyl-R beta-1,3-galactosyltransferase (configuration-inverting))

enzyme lambda metabolic reaction experiment
uniprot:Q9JJ05 [glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase(Enzyme) wildtype]

UDPgalactose + GalNAc_alpha1_O_phenyl -> beta_D_Galactosyl_1,3_N_acetyl_alpha_D_galactosamine_O_phenyl + UDP		 (( (Vmax * S) ) / (S + Km)) buffer: 100 mM MES, 0.2% Triton X-100, 20 mM MnCl2, 2 mM ATP.
PH: 6.8
Temperature: 37
uniprot:Q9JJ05 [glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase(Enzyme) wildtype]

GalNAc_alpha1_O_phenyl + UDPgalactose -> beta_D_Galactosyl_1,3_N_acetyl_alpha_D_galactosamine_O_phenyl + UDP		 (( (Vmax * S) ) / (S + Km)) buffer: 100 mM MES, 0.2% Triton X-100, 20 mM MnCl2, 2 mM ATP.
PH: 6.8
Temperature: 37

Pathways

pathway id name
BioCyc:META_PWY-7433 mucin core 1 and core 2 O-glycosylation
BioCyc:HUMAN_PWY-7433 mucin core 1 and core 2 O-glycosylation
BioCyc:META_PWY-7290 Escherichia coli serotype O86 O-antigen biosynthesis
Reactome:R-BTA-597592 Post-translational protein modification
Reactome:R-BTA-5173105 O-linked glycosylation
Reactome:R-GGA-597592 Post-translational protein modification
Reactome:R-GGA-913709 O-linked glycosylation of mucins
Reactome:R-HSA-392499 Metabolism of proteins
Reactome:R-HSA-597592 Post-translational protein modification
Reactome:R-HSA-5173105 O-linked glycosylation
Reactome:R-HSA-1643685 Disease
Reactome:R-HSA-3906995 Diseases associated with O-glycosylation of proteins
Reactome:R-RNO-597592 Post-translational protein modification
Reactome:R-RNO-5173105 O-linked glycosylation
Reactome:R-HSA-3781865 Diseases of glycosylation
Reactome:R-MMU-913709 O-linked glycosylation of mucins
Reactome:R-RNO-392499 Metabolism of proteins
Reactome:R-BTA-392499 Metabolism of proteins
Reactome:R-GGA-392499 Metabolism of proteins
Reactome:R-HSA-5668914 Diseases of metabolism
Reactome:R-HSA-5083632 Defective C1GALT1C1 causes TNPS
Reactome:R-MMU-392499 Metabolism of proteins
Reactome:R-MMU-597592 Post-translational protein modification
Reactome:R-MMU-5173105 O-linked glycosylation
Reactome:R-BTA-913709 O-linked glycosylation of mucins
Reactome:R-GGA-5173105 O-linked glycosylation
Reactome:R-HSA-913709 O-linked glycosylation of mucins
Reactome:R-RNO-913709 O-linked glycosylation of mucins