EC: 1.4.3.4

monoamine oxidase (amine:oxygen oxidoreductase (deaminating))

enzyme lambda metabolic reaction experiment
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y402A]

O2 + 2_Phenylethylamine + H2O -> H2O2 + NH3 + Phenylacetaldehyde		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) wildtype MAO-A]

O2 + 2_Phenylethylamine + H2O -> Phenylacetaldehyde + H2O2 + NH3		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y407F]

O2 + H2O + 2_Phenylethylamine -> H2O2 + Phenylacetaldehyde + NH3		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y402F]

H2O + 2_Phenylethylamine + O2 -> H2O2 + NH3 + Phenylacetaldehyde		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y410A]

O2 + Serotonin + H2O -> 5_Hydroxyindoleacetaldehyde + NH3 + H2O2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) wildtype MAO-A]

H2O + O2 + Serotonin -> NH3 + 5_Hydroxyindoleacetaldehyde + H2O2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y402F]

Serotonin + O2 + H2O -> NH3 + H2O2 + 5_Hydroxyindoleacetaldehyde		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y402A]

O2 + H2O + Serotonin -> NH3 + 5_Hydroxyindoleacetaldehyde + H2O2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y407F]

O2 + H2O + Serotonin -> 5_Hydroxyindoleacetaldehyde + NH3 + H2O2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) wildtype MAO-A]

Tyramine + O2 + H2O -> H2O2 + NH3 + 4_Hydroxyphenylacetaldehyde		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y402A]

O2 + H2O + Tyramine -> H2O2 + NH3 + 4_Hydroxyphenylacetaldehyde		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y407F]

Tyramine + O2 + H2O -> H2O2 + NH3 + 4_Hydroxyphenylacetaldehyde		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y402F]

Tyramine + H2O + O2 -> H2O2 + 4_Hydroxyphenylacetaldehyde + NH3		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y410A]

Tyramine + H2O + O2 -> H2O2 + NH3 + 4_Hydroxyphenylacetaldehyde		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y410A]

O2 + H2O + 2_Phenylethylamine -> H2O2 + Phenylacetaldehyde + NH3		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y402A]

Tryptamine + O2 + H2O -> NH3 + H2O2 + Indole_3_acetaldehyde		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) wildtype MAO-A]

Tryptamine + H2O + O2 -> NH3 + Indole_3_acetaldehyde + H2O2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y402F]

O2 + H2O + Tryptamine -> H2O2 + Indole_3_acetaldehyde + NH3		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y407A]

Tryptamine + O2 + H2O -> NH3 + Indole_3_acetaldehyde + H2O2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y410A]

H2O + Tryptamine + O2 -> H2O2 + NH3 + Indole_3_acetaldehyde		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [monoamine oxidase(Enzyme) mutant MAO-A Y407F]

O2 + H2O + Tryptamine -> Indole_3_acetaldehyde + NH3 + H2O2		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer:
PH: 7
Temperature: 30
uniprot:P21396 [FAD]

Tyramine + O2 + H2O -> NH3 + H2O2 + 4_Hydroxyphenylacetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

H2O + O2 + Serotonin -> NH3 + 5_Hydroxyindoleacetaldehyde + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P19643 [FAD]

O2 + Serotonin + H2O -> H2O2 + NH3 + 5_Hydroxyindoleacetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

H2O + Serotonin + O2 -> H2O2 + 5_Hydroxyindoleacetaldehyde + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

O2 + H2O + Tyramine -> H2O2 + NH3 + 4_Hydroxyphenylacetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P19643 [FAD]

O2 + H2O + Tyramine -> H2O2 + NH3 + 4_Hydroxyphenylacetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P19643 [FAD]

Tyramine + O2 + H2O -> 4_Hydroxyphenylacetaldehyde + H2O2 + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

Tyramine + O2 + H2O -> H2O2 + 4_Hydroxyphenylacetaldehyde + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

Tyramine + H2O + O2 -> 4_Hydroxyphenylacetaldehyde + H2O2 + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

Tyramine + O2 + H2O -> NH3 + 4_Hydroxyphenylacetaldehyde + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P19643 [FAD]

O2 + H2O + Tryptamine -> Indole_3_acetaldehyde + NH3 + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

H2O + Tryptamine + O2 -> NH3 + H2O2 + Indole_3_acetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P19643 [FAD]

H2O + O2 + Tryptamine -> NH3 + Indole_3_acetaldehyde + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

2_Phenylethylamine + O2 + H2O -> NH3 + H2O2 + Phenylacetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P19643 [FAD]

2_Phenylethylamine + O2 + H2O -> H2O2 + NH3 + Phenylacetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P19643 [FAD]

2_Phenylethylamine + H2O + O2 -> NH3 + Phenylacetaldehyde + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P19643 [FAD]

O2 + 2_Phenylethylamine + H2O -> H2O2 + NH3 + Phenylacetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P19643 [FAD]

O2 + H2O + 2_Phenylethylamine -> H2O2 + Phenylacetaldehyde + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

Tryptamine + O2 + H2O -> NH3 + Indole_3_acetaldehyde + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

Tryptamine + O2 + H2O -> NH3 + Indole_3_acetaldehyde + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

Tryptamine + O2 + H2O -> H2O2 + Indole_3_acetaldehyde + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

Tryptamine + O2 + H2O -> H2O2 + NH3 + Indole_3_acetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

O2 + 2_Phenylethylamine + H2O -> Phenylacetaldehyde + H2O2 + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

H2O + O2 + 2_Phenylethylamine -> Phenylacetaldehyde + NH3 + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

2_Phenylethylamine + O2 + H2O -> NH3 + H2O2 + Phenylacetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [FAD]

O2 + 2_Phenylethylamine + H2O -> H2O2 + NH3 + Phenylacetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) wildtype]

O2 + H2O + Benzylamine -> Benzaldehyde + H2O2 + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 0.3 M phosphate
PH: 7.5
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO AAB]

O2 + Serotonin + H2O -> H2O2 + 5_Hydroxyindoleacetaldehyde + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [monoamine oxidase(Enzyme) wildtype MAO A]

O2 + 2_Phenylethylamine + H2O -> H2O2 + NH3 + Phenylacetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [monoamine oxidase(Enzyme) wildtype MAO A]

Serotonin + H2O + O2 -> 5_Hydroxyindoleacetaldehyde + NH3 + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P21396 [monoamine oxidase(Enzyme) wildtype MAO A]

Benzylamine + H2O + O2 -> NH3 + Benzaldehyde + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO ABB]

2_Phenylethylamine + O2 + H2O -> Phenylacetaldehyde + NH3 + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO ABA]

2_Phenylethylamine + H2O + O2 -> NH3 + H2O2 + Phenylacetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO AAB]

H2O + 2_Phenylethylamine + O2 -> H2O2 + Phenylacetaldehyde + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO ABA]

H2O + O2 + Serotonin -> H2O2 + NH3 + 5_Hydroxyindoleacetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO ABB]

H2O + Serotonin + O2 -> NH3 + 5_Hydroxyindoleacetaldehyde + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO BBA]

H2O + Serotonin + O2 -> H2O2 + 5_Hydroxyindoleacetaldehyde + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO ABA]

H2O + Benzylamine + O2 -> H2O2 + NH3 + Benzaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO AAB]

O2 + H2O + Benzylamine -> Benzaldehyde + H2O2 + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO ABB]

H2O + Benzylamine + O2 -> H2O2 + NH3 + Benzaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO BBA]

2_Phenylethylamine + O2 + H2O -> H2O2 + Phenylacetaldehyde + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO (AB)BA]

2_Phenylethylamine + O2 + H2O -> NH3 + Phenylacetaldehyde + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P19643 [monoamine oxidase(Enzyme) wildtype MAO B]

2_Phenylethylamine + H2O + O2 -> NH3 + Phenylacetaldehyde + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO (AB)BA]

O2 + H2O + Serotonin -> 5_Hydroxyindoleacetaldehyde + H2O2 + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO (BA)AB]

H2O + Serotonin + O2 -> 5_Hydroxyindoleacetaldehyde + NH3 + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P19643 [monoamine oxidase(Enzyme) wildtype MAO B]

Serotonin + O2 + H2O -> H2O2 + NH3 + 5_Hydroxyindoleacetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO (AB)BA]

H2O + O2 + Benzylamine -> Benzaldehyde + H2O2 + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO BBA]

O2 + H2O + Benzylamine -> H2O2 + NH3 + Benzaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
uniprot:P19643 [monoamine oxidase(Enzyme) wildtype MAO B]

O2 + Benzylamine + H2O -> Benzaldehyde + H2O2 + NH3		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO (BA)AB]

2_Phenylethylamine + H2O + O2 -> NH3 + H2O2 + Phenylacetaldehyde		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37
- [monoamine oxidase(Enzyme) mutant chimeric protein MAO (BA)AB]

O2 + H2O + Benzylamine -> NH3 + Benzaldehyde + H2O2		 (( (Vmax * S) ) / (Km + S)) buffer: 50 mM Phosphate
PH: 7.4
Temperature: 37

Pathways

pathway id name
BioCyc:HUMAN_PWY-6307 tryptophan degradation via tryptamine
BioCyc:HUMAN_PWY66-401 superpathway of tryptophan utilization
BioCyc:HUMAN_PWY-6402 superpathway of melatonin degradation
BioCyc:META_PWY-6307 L-tryptophan degradation X (mammalian, via tryptamine)
BioCyc:META_PWY6666-2 dopamine degradation
BioCyc:META_PWY-6313 serotonin degradation
BioCyc:META_PWY-6342 noradrenaline and adrenaline degradation
BioCyc:MOUSE_THRDLCTCAT-PWY threonine degradation III (to methylglyoxal)
BioCyc:HUMAN_PWY-6313 serotonin degradation
BioCyc:META_PWY-0 putrescine degradation III
BioCyc:MOUSE_PWY6666-2 dopamine degradation
BioCyc:HUMAN_PWY6666-2 dopamine degradation
BioCyc:HUMAN_PWY-0 putrescine degradation III
BioCyc:HUMAN_PWY-6342 noradrenaline and adrenaline degradation
BioCyc:HUMAN_PWY-6399 melatonin degradation II
BioCyc:META_PWY-6318 L-phenylalanine degradation IV (mammalian, via side chain)
BioCyc:MOUSE_PWY-0 putrescine degradation III
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-211945 Phase I - Functionalization of compounds
Reactome:R-BTA-112310 Neurotransmitter release cycle
Reactome:R-BTA-379397 Enzymatic degradation of dopamine by COMT
Reactome:R-DRE-112315 Transmission across Chemical Synapses
Reactome:R-DRE-112311 Neurotransmitter clearance
Reactome:R-DRE-380615 Clearance of seratonin
Reactome:R-DRE-140179 Amine Oxidase reactions
Reactome:R-HSA-211859 Biological oxidations
Reactome:R-HSA-112315 Transmission across Chemical Synapses
Reactome:R-HSA-112311 Neurotransmitter clearance
Reactome:R-HSA-380615 Clearance of seratonin
Reactome:R-HSA-1643685 Disease
Reactome:R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-211859 Biological oxidations
Reactome:R-MMU-181430 Norepinephrine Neurotransmitter Release Cycle
Reactome:R-MMU-379398 Enzymatic degradation of Dopamine by monoamine oxidase
Reactome:R-RNO-211945 Phase I - Functionalization of compounds
Reactome:R-RNO-112316 Neuronal System
Reactome:R-RNO-379401 Clearance of dopamine
Reactome:R-RNO-380612 Metabolism of serotonin
Reactome:R-BTA-211859 Biological oxidations
Reactome:R-BTA-112316 Neuronal System
Reactome:R-BTA-379401 Clearance of dopamine
Reactome:R-BTA-380612 Metabolism of serotonin
Reactome:R-DRE-181430 Norepinephrine Neurotransmitter Release Cycle
Reactome:R-DRE-379398 Enzymatic degradation of Dopamine by monoamine oxidase
Reactome:R-DRE-211945 Phase I - Functionalization of compounds
Reactome:R-HSA-141333 Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB
Reactome:R-HSA-181430 Norepinephrine Neurotransmitter Release Cycle
Reactome:R-HSA-379398 Enzymatic degradation of Dopamine by monoamine oxidase
Reactome:R-HSA-5579012 Defective MAOA causes BRUNS
Reactome:R-HSA-449147 Signaling by Interleukins
Reactome:R-MMU-141333 Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB
Reactome:R-MMU-112310 Neurotransmitter release cycle
Reactome:R-MMU-379397 Enzymatic degradation of dopamine by COMT
Reactome:R-RNO-211859 Biological oxidations
Reactome:R-RNO-112315 Transmission across Chemical Synapses
Reactome:R-RNO-112311 Neurotransmitter clearance
Reactome:R-RNO-380615 Clearance of seratonin
Reactome:R-BTA-140179 Amine Oxidase reactions
Reactome:R-BTA-181430 Norepinephrine Neurotransmitter Release Cycle
Reactome:R-BTA-379398 Enzymatic degradation of Dopamine by monoamine oxidase
Reactome:R-DRE-112316 Neuronal System
Reactome:R-DRE-379401 Clearance of dopamine
Reactome:R-DRE-380612 Metabolism of serotonin
Reactome:R-DRE-1430728 Metabolism
Reactome:R-DRE-141333 Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB
Reactome:R-HSA-211945 Phase I - Functionalization of compounds
Reactome:R-HSA-112316 Neuronal System
Reactome:R-HSA-379401 Clearance of dopamine
Reactome:R-HSA-380612 Metabolism of serotonin
Reactome:R-HSA-5668914 Diseases of metabolism
Reactome:R-HSA-5579029 Metabolic disorders of biological oxidation enzymes
Reactome:R-HSA-168256 Immune System
Reactome:R-MMU-211945 Phase I - Functionalization of compounds
Reactome:R-MMU-112315 Transmission across Chemical Synapses
Reactome:R-MMU-112311 Neurotransmitter clearance
Reactome:R-MMU-380615 Clearance of seratonin
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-140179 Amine Oxidase reactions
Reactome:R-RNO-112310 Neurotransmitter release cycle
Reactome:R-RNO-379397 Enzymatic degradation of dopamine by COMT
Reactome:R-BTA-141333 Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB
Reactome:R-BTA-112315 Transmission across Chemical Synapses
Reactome:R-BTA-112311 Neurotransmitter clearance
Reactome:R-BTA-380615 Clearance of seratonin
Reactome:R-DRE-112310 Neurotransmitter release cycle
Reactome:R-DRE-379397 Enzymatic degradation of dopamine by COMT
Reactome:R-DRE-211859 Biological oxidations
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-140179 Amine Oxidase reactions
Reactome:R-HSA-112310 Neurotransmitter release cycle
Reactome:R-HSA-379397 Enzymatic degradation of dopamine by COMT
Reactome:R-HSA-1280215 Cytokine Signaling in Immune system
Reactome:R-MMU-140179 Amine Oxidase reactions
Reactome:R-MMU-112316 Neuronal System
Reactome:R-MMU-379401 Clearance of dopamine
Reactome:R-MMU-380612 Metabolism of serotonin
Reactome:R-RNO-141333 Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB
Reactome:R-RNO-181430 Norepinephrine Neurotransmitter Release Cycle
Reactome:R-RNO-379398 Enzymatic degradation of Dopamine by monoamine oxidase
WikiPathways:WP5298 Dravet syndrome: Scn1a-A1783V point mutation model
WikiPathways:WP4157 GABA metabolism (aka GHB)
WikiPathways:WP5372 Involvement of -secretase in neurodegenerative diseases
WikiPathways:WP4156 Biosynthesis and regeneration of tetrahydrobiopterin and catabolism of phenylalanine
PathBank:SMP0120540 Phenylketonuria
PathBank:SMP0000190 Hawkinsinuria
PathBank:SMP0000242 Dimethylglycine Dehydrogenase Deficiency
PathBank:SMP0000223 Non-Ketotic Hyperglycinemia
PathBank:SMP0000484 Dimethylglycine Dehydrogenase Deficiency
PathBank:SMP0120471 Cystathionine beta-Synthase Deficiency
PathBank:SMP0120487 Glycine N-Methyltransferase Deficiency
PathBank:SMP0120511 Tyrosinemia Type 3 (TYRO3)
PathBank:SMP0120519 Methionine Adenosyltransferase Deficiency
PathBank:SMP0120527 S-Adenosylhomocysteine (SAH) Hydrolase Deficiency
PathBank:SMP0000004 Glycine and Serine Metabolism
PathBank:SMP0000169 Alkaptonuria
PathBank:SMP0000429 Disulfiram Action Pathway
PathBank:SMP0000721 3-Phosphoglycerate Dehydrogenase Deficiency
PathBank:SMP0063637 Methionine Metabolism
PathBank:SMP0120461 Canavan Disease
PathBank:SMP0120513 Tyrosinemia Type 2 (or Richner-Hanhart Syndrome)
PathBank:SMP0120634 Homocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type
PathBank:SMP0000044 Histidine Metabolism
PathBank:SMP0000191 Histidinemia
PathBank:SMP0000218 Tyrosinemia Type I
PathBank:SMP0000179 Dihydropyrimidine Dehydrogenase Deficiency (DHPD)
PathBank:SMP0000485 Hyperglycinemia, Non-Ketotic
PathBank:SMP0000533 Monoamine Oxidase-A Deficiency (MAO-A)
PathBank:SMP0120498 Hypermethioninemia
PathBank:SMP0120502 Hypoacetylaspartia
PathBank:SMP0000006 Tyrosine Metabolism
PathBank:SMP0000244 Sarcosinemia
PathBank:SMP0000424 Citalopram Action Pathway
PathBank:SMP0000494 Tyrosinemia, Transient, of the Newborn
PathBank:SMP0000498 Dopamine beta-Hydroxylase Deficiency
PathBank:SMP0000627 Citalopram Metabolism Pathway
PathBank:SMP0063597 Aspartate Metabolism
PathBank:SMP0063649 Phenylalanine and Tyrosine Metabolism