EC: 1.1.1.4

(R,R)-butanediol dehydrogenase ((R,R)-butane-2,3-diol:NAD+ oxidoreductase)

enzyme lambda metabolic reaction experiment
uniprot:Q0KDL6 [(R,R)-butanediol dehydrogenase(Enzyme) wildtype]

NAD+ + erythro_2,3_Butanediol -> H+ + Acetoin + NADH		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM Glycine/NaOH
PH: 9.2
Temperature: 30
uniprot:Q0KDL6 [(R,R)-butanediol dehydrogenase(Enzyme) wildtype]

erythro_2,3_Butanediol + NAD+ -> Acetoin + H+ + NADH		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 100 mM Glycine/NaOH
PH: 9.2
Temperature: 30
uniprot:Q0KDL6 [(R,R)-butanediol dehydrogenase(Enzyme) wildtype]

NAD+ + threo_2,3_Butanediol -> Acetoin + NADH + H+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM Glycine/NaOH
PH: 9.2
Temperature: 30
uniprot:Q0KDL6 [(R,R)-butanediol dehydrogenase(Enzyme) wildtype]

threo_2,3_Butanediol + NAD+ -> Acetoin + H+ + NADH		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 100 mM Glycine/NaOH
PH: 9.2
Temperature: 30
uniprot:Q0KDL6 [(R,R)-butanediol dehydrogenase(Enzyme) wildtype]

NADH + H+ + Acetoin -> 2,3_Butanediol + NAD+		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM Citrate
PH: 5.8
Temperature: 30
uniprot:Q0KDL6 [(R,R)-butanediol dehydrogenase(Enzyme) wildtype]

Acetoin + H+ + NADH -> 2,3_Butanediol + NAD+		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 100 mM Citrate
PH: 5.8
Temperature: 30
uniprot:Q0KDL6 [(R,R)-butanediol dehydrogenase(Enzyme) wildtype]

Acetoin + NADPH + H+ -> 2,3_Butanediol + NADP+		 (( (( (E * kcat) ) * B) ) / (Km + B)) buffer: 100 mM Citrate
PH: 5.8
Temperature: 30
uniprot:Q0KDL6 [(R,R)-butanediol dehydrogenase(Enzyme) wildtype]

NADPH + H+ + Acetoin -> NADP+ + 2,3_Butanediol		 (( (( (E * kcat) ) * A) ) / (Km + A)) buffer: 100 mM Citrate
PH: 5.8
Temperature: 30

Pathways

pathway id name
BioCyc:META_PWY-6396 superpathway of 2,3-butanediol biosynthesis
BioCyc:YEAST_PWY3O-981 superpathway of acetoin and butanediol biosynthesis
BioCyc:YEAST_PWY3O-246 (R,R)-butanediol degradation
BioCyc:BSUB_P125-PWY superpathway of (R,R)-butanediol biosynthesis
BioCyc:META_PWY-6392 meso-butanediol biosynthesis II
BioCyc:YEAST_PWY-5938 (R)-acetoin biosynthesis I
BioCyc:YEAST_PWY3O-661 butanediol biosynthesis
BioCyc:HUMAN_PWY-4101 sorbitol degradation I
BioCyc:YEAST_PWY-6392 meso-butanediol biosynthesis II
BioCyc:META_PWY3O-246 (R,R)-butanediol degradation
BioCyc:META_PWY-5938 pyruvate fermentation to (R)-acetoin I
BioCyc:META_PWY-5951 (R,R)-butanediol biosynthesis
BioCyc:YEAST_PWY-5951 (R,R)-butanediol biosynthesis
BioCyc:BSUB_PWY3O-246 (R,R)-butanediol degradation
BioCyc:BSUB_PWY-5951 (R,R)-butanediol biosynthesis
Reactome:R-HSA-5661270 Formation of xylulose-5-phosphate
Reactome:R-HSA-71387 Carbohydrate metabolism
Reactome:R-HSA-5652084 Fructose metabolism
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-5652227 Fructose biosynthesis
WikiPathways:WP5283 Chronic hyperglycemia impairment of neuron function
PathBank:SMP0000064 Fructose and Mannose Degradation
PathBank:SMP0000725 Fructose Intolerance, Hereditary
PathBank:SMP0000561 Fructosuria