EC: 3.5.1.98

histone deacetylase (histone amidohydrolase)

enzyme lambda metabolic reaction experiment
- [histone deacetylase(Enzyme) wildtype HD2]

Acetylhistone + H2O -> Histone + Acetate
(( (Vmax * A) ) / (Km + A)) buffer: not available
PH: 7.5
Temperature: 30

Pathways

pathway id name
Reactome:R-RNO-9029569 LXRs regulate gene expression linked to cholesterol transport and efflux
Reactome:R-MMU-9029569 LXRs regulate gene expression linked to cholesterol transport and efflux
Reactome:R-HSA-9609690 HCMV Early Events
Reactome:R-RNO-9024446 LXR-mediated signaling
Reactome:R-MMU-9024446 LXR-mediated signaling
Reactome:R-HSA-9609646 HCMV Infection
Reactome:R-HSA-9029569 LXRs regulate gene expression linked to cholesterol transport and efflux
Reactome:R-HSA-9024446 LXR-mediated signaling
Reactome:R-HSA-9619665 EGR2 and SOX10-mediated initiation of Schwann cell myelination
Reactome:R-HSA-9675151 Disorders of Developmental Biology
Reactome:R-DDI-3214815 HDACs deacetylate histones
Reactome:R-HSA-9700206 Signaling by ALK in cancer
Reactome:R-DME-9856651 MITF-M-dependent gene expression
Reactome:R-GGA-9730414 MITF-M-regulated melanocyte development
Reactome:R-HSA-9856651 MITF-M-dependent gene expression
Reactome:R-HSA-9843745 Adipogenesis
Reactome:R-HSA-9675108 Nervous system development
Reactome:R-RNO-3214815 HDACs deacetylate histones
Reactome:R-HSA-9697154 Disorders of Nervous System Development
Reactome:R-BTA-9730414 MITF-M-regulated melanocyte development
Reactome:R-GGA-9824594 Regulation of MITF-M-dependent genes involved in apoptosis
Reactome:R-HSA-9856649 Transcriptional and post-translational regulation of MITF-M expression and activity
Reactome:R-HSA-9824594 Regulation of MITF-M-dependent genes involved in apoptosis
Reactome:R-MMU-9730414 MITF-M-regulated melanocyte development
Reactome:R-MMU-9843745 Adipogenesis
Reactome:R-RNO-9730414 MITF-M-regulated melanocyte development
Reactome:R-RNO-9843745 Adipogenesis
Reactome:R-HSA-9707616 Heme signaling
Reactome:R-HSA-9725370 Signaling by ALK fusions and activated point mutants
Reactome:R-HSA-9824446 Viral Infection Pathways
Reactome:R-BTA-9759476 Regulation of Homotypic Cell-Cell Adhesion
Reactome:R-HSA-9759476 Regulation of Homotypic Cell-Cell Adhesion
Reactome:R-RNO-9759476 Regulation of Homotypic Cell-Cell Adhesion
Reactome:R-BTA-9856651 MITF-M-dependent gene expression
Reactome:R-DME-9824594 Regulation of MITF-M-dependent genes involved in apoptosis
Reactome:R-HSA-9843743 Transcriptional regulation of brown and beige adipocyte differentiation
Reactome:R-MMU-9856651 MITF-M-dependent gene expression
Reactome:R-RNO-9856651 MITF-M-dependent gene expression
Reactome:R-HSA-9725371 Nuclear events stimulated by ALK signaling in cancer
Reactome:R-DME-9759476 Regulation of Homotypic Cell-Cell Adhesion
Reactome:R-GGA-9759476 Regulation of Homotypic Cell-Cell Adhesion
Reactome:R-MMU-9759476 Regulation of Homotypic Cell-Cell Adhesion
Reactome:R-BTA-9824594 Regulation of MITF-M-dependent genes involved in apoptosis
Reactome:R-DME-9730414 MITF-M-regulated melanocyte development
Reactome:R-GGA-9856651 MITF-M-dependent gene expression
Reactome:R-HSA-9730414 MITF-M-regulated melanocyte development
Reactome:R-HSA-9825892 Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
Reactome:R-HSA-9844594 Transcriptional regulation of brown and beige adipocyte differentiation by EBF2
Reactome:R-MMU-9824594 Regulation of MITF-M-dependent genes involved in apoptosis
Reactome:R-RNO-9824594 Regulation of MITF-M-dependent genes involved in apoptosis
Reactome:R-HSA-9818564 Epigenetic regulation of gene expression by MLL3 and MLL4 complexes
Reactome:R-HSA-9845323 Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Reactome:R-RNO-9825892 Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
Reactome:R-RNO-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes
Reactome:R-BTA-9764725 Negative Regulation of CDH1 Gene Transcription
Reactome:R-DME-9764274 Regulation of Expression and Function of Type I Classical Cadherins
Reactome:R-GGA-9764560 Regulation of CDH1 Gene Transcription
Reactome:R-HSA-9764265 Regulation of CDH1 Expression and Function
Reactome:R-MMU-9764265 Regulation of CDH1 Expression and Function
Reactome:R-RNO-9764725 Negative Regulation of CDH1 Gene Transcription
Reactome:R-HSA-9917777 Epigenetic regulation by WDR5-containing histone modifying complexes
Reactome:R-HSA-9842860 Regulation of endogenous retroelements
Reactome:R-MMU-9825892 Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
Reactome:R-RNO-9841922 MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Reactome:R-BTA-9764560 Regulation of CDH1 Gene Transcription
Reactome:R-DME-9764725 Negative Regulation of CDH1 Gene Transcription
Reactome:R-GGA-9764265 Regulation of CDH1 Expression and Function
Reactome:R-HSA-9764274 Regulation of Expression and Function of Type I Classical Cadherins
Reactome:R-HSA-9764725 Negative Regulation of CDH1 Gene Transcription
Reactome:R-MMU-9764274 Regulation of Expression and Function of Type I Classical Cadherins
Reactome:R-RNO-9764560 Regulation of CDH1 Gene Transcription
Reactome:R-HSA-9851695 Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes
Reactome:R-HSA-9843940 Regulation of endogenous retroelements by KRAB-ZFP proteins
Reactome:R-RNO-9818564 Epigenetic regulation of gene expression by MLL3 and MLL4 complexes
Reactome:R-HSA-9909396 Circadian clock
Reactome:R-HSA-9933387 RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression
Reactome:R-BTA-9764274 Regulation of Expression and Function of Type I Classical Cadherins
Reactome:R-DME-9764265 Regulation of CDH1 Expression and Function
Reactome:R-GGA-9764725 Negative Regulation of CDH1 Gene Transcription
Reactome:R-HSA-9764560 Regulation of CDH1 Gene Transcription
Reactome:R-MMU-9764560 Regulation of CDH1 Gene Transcription
Reactome:R-RNO-9764274 Regulation of Expression and Function of Type I Classical Cadherins
Reactome:R-BTA-9825892 Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
Reactome:R-DME-9825892 Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
Reactome:R-GGA-9825892 Regulation of MITF-M-dependent genes involved in cell cycle and proliferation
Reactome:R-HSA-9841922 MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Reactome:R-RNO-9851695 Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes
Reactome:R-HSA-9931509 Expression of BMAL (ARNTL), CLOCK, and NPAS2
Reactome:R-BTA-9764265 Regulation of CDH1 Expression and Function
Reactome:R-DME-9764560 Regulation of CDH1 Gene Transcription
Reactome:R-GGA-9764274 Regulation of Expression and Function of Type I Classical Cadherins
Reactome:R-MMU-9764725 Negative Regulation of CDH1 Gene Transcription
Reactome:R-RNO-9764265 Regulation of CDH1 Expression and Function
Reactome:R-DME-418990 Adherens junctions interactions
Reactome:R-DME-421270 Cell-cell junction organization
Reactome:R-BTA-597592 Post-translational protein modification
Reactome:R-BTA-2990846 SUMOylation
Reactome:R-BTA-74160 Gene expression (Transcription)
Reactome:R-BTA-73857 RNA Polymerase II Transcription
Reactome:R-BTA-3700989 Transcriptional Regulation by TP53
Reactome:R-BTA-5633007 Regulation of TP53 Activity
Reactome:R-BTA-1640170 Cell Cycle
Reactome:R-BTA-1538133 G0 and Early G1
Reactome:R-BTA-109582 Hemostasis
Reactome:R-BTA-1500931 Cell-Cell communication
Reactome:R-BTA-170834 Signaling by TGF-beta Receptor Complex
Reactome:R-BTA-8939211 ESR-mediated signaling
Reactome:R-BTA-6807070 PTEN Regulation
Reactome:R-DRE-3247509 Chromatin modifying enzymes
Reactome:R-DDI-3247509 Chromatin modifying enzymes
Reactome:R-DDI-597592 Post-translational protein modification
Reactome:R-DDI-3108232 SUMO E3 ligases SUMOylate target proteins
Reactome:R-DDI-4551638 SUMOylation of chromatin organization proteins
Reactome:R-DDI-1538133 G0 and Early G1
Reactome:R-DME-195721 Signaling by WNT
Reactome:R-DME-201722 Formation of the beta-catenin:TCF transactivating complex
Reactome:R-DME-9006931 Signaling by Nuclear Receptors
Reactome:R-DME-9018519 Estrogen-dependent gene expression
Reactome:R-DME-8943724 Regulation of PTEN gene transcription
Reactome:R-DME-69278 Cell Cycle, Mitotic
Reactome:R-DME-1266738 Developmental Biology
Reactome:R-DME-446728 Cell junction organization
Reactome:R-DME-983231 Factors involved in megakaryocyte development and platelet production
Reactome:R-GGA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity
Reactome:R-GGA-5633007 Regulation of TP53 Activity
Reactome:R-GGA-8878159 Transcriptional regulation by RUNX3
Reactome:R-GGA-446728 Cell junction organization
Reactome:R-GGA-9006936 Signaling by TGFB family members
Reactome:R-GGA-195721 Signaling by WNT
Reactome:R-GGA-201722 Formation of the beta-catenin:TCF transactivating complex
Reactome:R-GGA-9006925 Intracellular signaling by second messengers
Reactome:R-GGA-6807070 PTEN Regulation
Reactome:R-GGA-597592 Post-translational protein modification
Reactome:R-GGA-983231 Factors involved in megakaryocyte development and platelet production
Reactome:R-HSA-418990 Adherens junctions interactions
Reactome:R-HSA-400206 Regulation of lipid metabolism by PPARalpha
Reactome:R-HSA-9006936 Signaling by TGFB family members
Reactome:R-HSA-201681 TCF dependent signaling in response to WNT
Reactome:R-HSA-9006925 Intracellular signaling by second messengers
Reactome:R-HSA-392499 Metabolism of proteins
Reactome:R-HSA-597592 Post-translational protein modification
Reactome:R-HSA-2990846 SUMOylation
Reactome:R-HSA-4090294 SUMOylation of intracellular receptors
Reactome:R-HSA-1643685 Disease
Reactome:R-HSA-3214815 HDACs deacetylate histones
Reactome:R-HSA-74160 Gene expression (Transcription)
Reactome:R-HSA-73857 RNA Polymerase II Transcription
Reactome:R-HSA-6804758 Regulation of TP53 Activity through Acetylation
Reactome:R-HSA-8941326 RUNX2 regulates bone development
Reactome:R-HSA-9022692 Regulation of MECP2 expression and activity
Reactome:R-HSA-427389 Activation of rRNA Expression by ERCC6 (CSB) and EHMT2 (G9a)
Reactome:R-MMU-1640170 Cell Cycle
Reactome:R-MMU-1538133 G0 and Early G1
Reactome:R-MMU-381340 Transcriptional regulation of white adipocyte differentiation
Reactome:R-MMU-418990 Adherens junctions interactions
Reactome:R-MMU-74160 Gene expression (Transcription)
Reactome:R-MMU-73857 RNA Polymerase II Transcription
Reactome:R-MMU-3700989 Transcriptional Regulation by TP53
Reactome:R-MMU-5633007 Regulation of TP53 Activity
Reactome:R-MMU-162582 Signaling Pathways
Reactome:R-MMU-6807070 PTEN Regulation
Reactome:R-RNO-597592 Post-translational protein modification
Reactome:R-RNO-2990846 SUMOylation
Reactome:R-RNO-4090294 SUMOylation of intracellular receptors
Reactome:R-RNO-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity
Reactome:R-RNO-6804758 Regulation of TP53 Activity through Acetylation
Reactome:R-RNO-8878171 Transcriptional regulation by RUNX1
Reactome:R-RNO-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Reactome:R-RNO-421270 Cell-cell junction organization
Reactome:R-RNO-162582 Signaling Pathways
Reactome:R-RNO-9006936 Signaling by TGFB family members
Reactome:R-RNO-9006931 Signaling by Nuclear Receptors
Reactome:R-RNO-9018519 Estrogen-dependent gene expression
Reactome:R-RNO-8943724 Regulation of PTEN gene transcription
Reactome:R-RNO-109582 Hemostasis
Reactome:R-RNO-1266738 Developmental Biology
Reactome:R-SCE-8953897 Cellular responses to stimuli
Reactome:R-SCE-3371556 Cellular response to heat stress
Reactome:R-SCE-597592 Post-translational protein modification
Reactome:R-SCE-3108232 SUMO E3 ligases SUMOylate target proteins
Reactome:R-XTR-4839726 Chromatin organization
Reactome:R-BTA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity
Reactome:R-BTA-6804758 Regulation of TP53 Activity through Acetylation
Reactome:R-BTA-453279 Mitotic G1 phase and G1/S transition
Reactome:R-BTA-1266738 Developmental Biology
Reactome:R-BTA-418990 Adherens junctions interactions
Reactome:R-BTA-162582 Signaling Pathways
Reactome:R-BTA-9006936 Signaling by TGFB family members
Reactome:R-BTA-1257604 PI3K/AKT Signaling
Reactome:R-DRE-4839726 Chromatin organization
Reactome:R-DDI-4839726 Chromatin organization
Reactome:R-DDI-392499 Metabolism of proteins
Reactome:R-DDI-2990846 SUMOylation
Reactome:R-DDI-453279 Mitotic G1 phase and G1/S transition
Reactome:R-DME-162582 Signaling Pathways
Reactome:R-DME-8939211 ESR-mediated signaling
Reactome:R-DME-6807070 PTEN Regulation
Reactome:R-DME-1500931 Cell-Cell communication
Reactome:R-DME-8878171 Transcriptional regulation by RUNX1
Reactome:R-DME-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Reactome:R-DME-109582 Hemostasis
Reactome:R-DME-209459 Imd pathway
Reactome:R-GGA-1500931 Cell-Cell communication
Reactome:R-GGA-1640170 Cell Cycle
Reactome:R-GGA-1538133 G0 and Early G1
Reactome:R-GGA-9006931 Signaling by Nuclear Receptors
Reactome:R-GGA-9018519 Estrogen-dependent gene expression
Reactome:R-GGA-4090294 SUMOylation of intracellular receptors
Reactome:R-HSA-1592230 Mitochondrial biogenesis
Reactome:R-HSA-1266738 Developmental Biology
Reactome:R-HSA-421270 Cell-cell junction organization
Reactome:R-HSA-556833 Metabolism of lipids
Reactome:R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity
Reactome:R-HSA-195721 Signaling by WNT
Reactome:R-HSA-4641265 Repression of WNT target genes
Reactome:R-HSA-201722 Formation of the beta-catenin:TCF transactivating complex
Reactome:R-HSA-9006931 Signaling by Nuclear Receptors
Reactome:R-HSA-9018519 Estrogen-dependent gene expression
Reactome:R-HSA-8943724 Regulation of PTEN gene transcription
Reactome:R-HSA-2262752 Cellular responses to stress
Reactome:R-HSA-1640170 Cell Cycle
Reactome:R-HSA-1538133 G0 and Early G1
Reactome:R-HSA-9022537 Loss of MECP2 binding ability to the NCoR/SMRT complex
Reactome:R-HSA-8986944 Transcriptional Regulation by MECP2
Reactome:R-HSA-212165 Epigenetic regulation of gene expression
Reactome:R-HSA-427413 NoRC negatively regulates rRNA expression
Reactome:R-MMU-453279 Mitotic G1 phase and G1/S transition
Reactome:R-MMU-983231 Factors involved in megakaryocyte development and platelet production
Reactome:R-MMU-421270 Cell-cell junction organization
Reactome:R-MMU-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity
Reactome:R-MMU-6804758 Regulation of TP53 Activity through Acetylation
Reactome:R-MMU-8951936 RUNX3 regulates p14-ARF
Reactome:R-MMU-1257604 PI3K/AKT Signaling
Reactome:R-RNO-1640170 Cell Cycle
Reactome:R-RNO-1538133 G0 and Early G1
Reactome:R-RNO-392499 Metabolism of proteins
Reactome:R-RNO-8878159 Transcriptional regulation by RUNX3
Reactome:R-RNO-446728 Cell junction organization
Reactome:R-RNO-8939211 ESR-mediated signaling
Reactome:R-RNO-6807070 PTEN Regulation
Reactome:R-RNO-983231 Factors involved in megakaryocyte development and platelet production
Reactome:R-RNO-381340 Transcriptional regulation of white adipocyte differentiation
Reactome:R-SCE-2990846 SUMOylation
Reactome:R-SCE-4551638 SUMOylation of chromatin organization proteins
Reactome:R-SPO-2262752 Cellular responses to stress
Reactome:R-XTR-3214815 HDACs deacetylate histones
Reactome:R-BTA-392499 Metabolism of proteins
Reactome:R-BTA-3108232 SUMO E3 ligases SUMOylate target proteins
Reactome:R-BTA-4551638 SUMOylation of chromatin organization proteins
Reactome:R-BTA-212436 Generic Transcription Pathway
Reactome:R-BTA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Reactome:R-BTA-983231 Factors involved in megakaryocyte development and platelet production
Reactome:R-BTA-446728 Cell junction organization
Reactome:R-BTA-195721 Signaling by WNT
Reactome:R-BTA-201722 Formation of the beta-catenin:TCF transactivating complex
Reactome:R-BTA-9006931 Signaling by Nuclear Receptors
Reactome:R-BTA-9018519 Estrogen-dependent gene expression
Reactome:R-BTA-8943724 Regulation of PTEN gene transcription
Reactome:R-DDI-1640170 Cell Cycle
Reactome:R-DME-201681 TCF dependent signaling in response to WNT
Reactome:R-DME-3769402 Deactivation of the beta-catenin transactivating complex
Reactome:R-DME-9006925 Intracellular signaling by second messengers
Reactome:R-DME-453279 Mitotic G1 phase and G1/S transition
Reactome:R-DME-74160 Gene expression (Transcription)
Reactome:R-DME-73857 RNA Polymerase II Transcription
Reactome:R-DME-3700989 Transcriptional Regulation by TP53
Reactome:R-DME-6804758 Regulation of TP53 Activity through Acetylation
Reactome:R-DME-5252538 Drosophila signaling pathways
Reactome:R-DME-209394 Transcriptional activtion and repression of REL-68 target genes
Reactome:R-GGA-74160 Gene expression (Transcription)
Reactome:R-GGA-73857 RNA Polymerase II Transcription
Reactome:R-GGA-3700989 Transcriptional Regulation by TP53
Reactome:R-GGA-421270 Cell-cell junction organization
Reactome:R-GGA-69278 Cell Cycle, Mitotic
Reactome:R-GGA-170834 Signaling by TGF-beta Receptor Complex
Reactome:R-GGA-201681 TCF dependent signaling in response to WNT
Reactome:R-GGA-3769402 Deactivation of the beta-catenin transactivating complex
Reactome:R-GGA-1257604 PI3K/AKT Signaling
Reactome:R-GGA-8943724 Regulation of PTEN gene transcription
Reactome:R-GGA-392499 Metabolism of proteins
Reactome:R-GGA-3108232 SUMO E3 ligases SUMOylate target proteins
Reactome:R-GGA-4551638 SUMOylation of chromatin organization proteins
Reactome:R-GGA-109582 Hemostasis
Reactome:R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis
Reactome:R-HSA-381340 Transcriptional regulation of white adipocyte differentiation
Reactome:R-HSA-5619507 Activation of HOX genes during differentiation
Reactome:R-HSA-1500931 Cell-Cell communication
Reactome:R-HSA-109582 Hemostasis
Reactome:R-HSA-1989781 PPARA activates gene expression
Reactome:R-HSA-170834 Signaling by TGF-beta Receptor Complex
Reactome:R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Reactome:R-HSA-195253 Degradation of beta-catenin by the destruction complex
Reactome:R-HSA-3769402 Deactivation of the beta-catenin transactivating complex
Reactome:R-HSA-1257604 PI3K/AKT Signaling
Reactome:R-HSA-69278 Cell Cycle, Mitotic
Reactome:R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
Reactome:R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins
Reactome:R-HSA-4551638 SUMOylation of chromatin organization proteins
Reactome:R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers
Reactome:R-HSA-9005895 Pervasive developmental disorders
Reactome:R-HSA-4839726 Chromatin organization
Reactome:R-HSA-212436 Generic Transcription Pathway
Reactome:R-HSA-3700989 Transcriptional Regulation by TP53
Reactome:R-HSA-5633007 Regulation of TP53 Activity
Reactome:R-HSA-8878171 Transcriptional regulation by RUNX1
Reactome:R-HSA-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Reactome:R-HSA-8940973 RUNX2 regulates osteoblast differentiation
Reactome:R-HSA-8878159 Transcriptional regulation by RUNX3
Reactome:R-HSA-8951936 RUNX3 regulates p14-ARF
Reactome:R-HSA-5250941 Negative epigenetic regulation of rRNA expression
Reactome:R-MMU-1266738 Developmental Biology
Reactome:R-MMU-1500931 Cell-Cell communication
Reactome:R-MMU-212436 Generic Transcription Pathway
Reactome:R-MMU-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Reactome:R-MMU-8878159 Transcriptional regulation by RUNX3
Reactome:R-MMU-9006936 Signaling by TGFB family members
Reactome:R-MMU-195721 Signaling by WNT
Reactome:R-MMU-201722 Formation of the beta-catenin:TCF transactivating complex
Reactome:R-MMU-9006931 Signaling by Nuclear Receptors
Reactome:R-MMU-8943724 Regulation of PTEN gene transcription
Reactome:R-MMU-392499 Metabolism of proteins
Reactome:R-MMU-597592 Post-translational protein modification
Reactome:R-MMU-2990846 SUMOylation
Reactome:R-MMU-4090294 SUMOylation of intracellular receptors
Reactome:R-RNO-4839726 Chromatin organization
Reactome:R-RNO-69278 Cell Cycle, Mitotic
Reactome:R-RNO-3108232 SUMO E3 ligases SUMOylate target proteins
Reactome:R-RNO-4551638 SUMOylation of chromatin organization proteins
Reactome:R-RNO-74160 Gene expression (Transcription)
Reactome:R-RNO-73857 RNA Polymerase II Transcription
Reactome:R-RNO-3700989 Transcriptional Regulation by TP53
Reactome:R-RNO-5633007 Regulation of TP53 Activity
Reactome:R-RNO-8951936 RUNX3 regulates p14-ARF
Reactome:R-RNO-418990 Adherens junctions interactions
Reactome:R-RNO-170834 Signaling by TGF-beta Receptor Complex
Reactome:R-RNO-195721 Signaling by WNT
Reactome:R-RNO-201722 Formation of the beta-catenin:TCF transactivating complex
Reactome:R-RNO-9006925 Intracellular signaling by second messengers
Reactome:R-SCE-3371511 HSF1 activation
Reactome:R-SPO-392499 Metabolism of proteins
Reactome:R-SPO-2990846 SUMOylation
Reactome:R-SPO-4551638 SUMOylation of chromatin organization proteins
Reactome:R-SPO-8953897 Cellular responses to stimuli
Reactome:R-SPO-3371556 Cellular response to heat stress
Reactome:R-XTR-3247509 Chromatin modifying enzymes
Reactome:R-BTA-8878171 Transcriptional regulation by RUNX1
Reactome:R-BTA-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Reactome:R-BTA-69278 Cell Cycle, Mitotic
Reactome:R-BTA-421270 Cell-cell junction organization
Reactome:R-BTA-201681 TCF dependent signaling in response to WNT
Reactome:R-BTA-3769402 Deactivation of the beta-catenin transactivating complex
Reactome:R-BTA-9006925 Intracellular signaling by second messengers
Reactome:R-DRE-3214815 HDACs deacetylate histones
Reactome:R-DDI-69278 Cell Cycle, Mitotic
Reactome:R-DME-1257604 PI3K/AKT Signaling
Reactome:R-DME-1640170 Cell Cycle
Reactome:R-DME-1538133 G0 and Early G1
Reactome:R-DME-212436 Generic Transcription Pathway
Reactome:R-DME-5633007 Regulation of TP53 Activity
Reactome:R-GGA-212436 Generic Transcription Pathway
Reactome:R-GGA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Reactome:R-GGA-6804758 Regulation of TP53 Activity through Acetylation
Reactome:R-GGA-8878171 Transcriptional regulation by RUNX1
Reactome:R-GGA-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Reactome:R-GGA-8951936 RUNX3 regulates p14-ARF
Reactome:R-GGA-418990 Adherens junctions interactions
Reactome:R-GGA-453279 Mitotic G1 phase and G1/S transition
Reactome:R-GGA-162582 Signaling Pathways
Reactome:R-GGA-8939211 ESR-mediated signaling
Reactome:R-GGA-1266738 Developmental Biology
Reactome:R-GGA-2990846 SUMOylation
Reactome:R-HSA-1852241 Organelle biogenesis and maintenance
Reactome:R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis
Reactome:R-HSA-446728 Cell junction organization
Reactome:R-HSA-983231 Factors involved in megakaryocyte development and platelet production
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-162582 Signaling Pathways
Reactome:R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Reactome:R-HSA-8939211 ESR-mediated signaling
Reactome:R-HSA-6807070 PTEN Regulation
Reactome:R-HSA-8953897 Cellular responses to stimuli
Reactome:R-HSA-453279 Mitotic G1 phase and G1/S transition
Reactome:R-HSA-5663205 Infectious disease
Reactome:R-HSA-9005891 Loss of function of MECP2 in Rett syndrome
Reactome:R-HSA-3247509 Chromatin modifying enzymes
Reactome:R-HSA-8878166 Transcriptional regulation by RUNX2
Reactome:R-HSA-8941284 RUNX2 regulates chondrocyte maturation
Reactome:R-HSA-5250913 Positive epigenetic regulation of rRNA expression
Reactome:R-MMU-69278 Cell Cycle, Mitotic
Reactome:R-MMU-109582 Hemostasis
Reactome:R-MMU-446728 Cell junction organization
Reactome:R-MMU-8878171 Transcriptional regulation by RUNX1
Reactome:R-MMU-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Reactome:R-MMU-170834 Signaling by TGF-beta Receptor Complex
Reactome:R-MMU-201681 TCF dependent signaling in response to WNT
Reactome:R-MMU-3769402 Deactivation of the beta-catenin transactivating complex
Reactome:R-MMU-9006925 Intracellular signaling by second messengers
Reactome:R-MMU-3108232 SUMO E3 ligases SUMOylate target proteins
Reactome:R-MMU-4551638 SUMOylation of chromatin organization proteins
Reactome:R-RNO-3247509 Chromatin modifying enzymes
Reactome:R-RNO-453279 Mitotic G1 phase and G1/S transition
Reactome:R-RNO-212436 Generic Transcription Pathway
Reactome:R-RNO-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Reactome:R-RNO-212165 Epigenetic regulation of gene expression
Reactome:R-RNO-1500931 Cell-Cell communication
Reactome:R-RNO-201681 TCF dependent signaling in response to WNT
Reactome:R-RNO-3769402 Deactivation of the beta-catenin transactivating complex
Reactome:R-RNO-1257604 PI3K/AKT Signaling
Reactome:R-SCE-2262752 Cellular responses to stress
Reactome:R-SCE-392499 Metabolism of proteins
Reactome:R-SPO-597592 Post-translational protein modification
Reactome:R-SPO-3108232 SUMO E3 ligases SUMOylate target proteins
Reactome:R-SPO-3371511 HSF1 activation
WikiPathways:WP5158 Urotensin-II-mediated signaling pathway
WikiPathways:WP1984 Integrated breast cancer pathway