EC: 2.7.1.158

inositol-pentakisphosphate 2-kinase (ATP:1D-myo-inositol 1,3,4,5,6-pentakisphosphate 2-phosphotransferase)

enzyme lambda metabolic reaction experiment
uniprot:Q9H8X2 [inositol-pentakisphosphate 2-kinase(Enzyme) wildtype His- and FLAG-tagged]

ATP + 1D_myo_Inositol_1,3,4,5,6_pentakisphosphate -> myo_Inositol_hexakisphosphate + ADP		 (( (Vmax * A) ) / (Km + A)) buffer: 50 mM HEPES, 100 mM KCl, 1 mM DTT, 10 mM MgCl2
PH: 7
Temperature: 37
uniprot:Q9H8X2 [inositol-pentakisphosphate 2-kinase(Enzyme) wildtype His- and FLAG-tagged]

1D_myo_Inositol_1,3,4,5,6_pentakisphosphate + ATP -> myo_Inositol_hexakisphosphate + ADP		 (( (Vmax * B) ) / (Km + B)) buffer: 50 mM HEPES, 100 mM KCl, 1 mM DTT, 10 mM MgCl2
PH: 7
Temperature: 37

Pathways

pathway id name
BioCyc:HUMAN_PWY-6369 inositol pyrophosphates biosynthesis
BioCyc:META_PWY-6362 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)
BioCyc:META_PWY-6371 superpathway of inositol phosphate compounds
BioCyc:YEAST_PWY3O-402 inositol phosphate biosynthesis
BioCyc:HUMAN_PWY-6554 1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)
BioCyc:HUMAN_PWY-6362 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)
BioCyc:META_PWY-6361 1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)
BioCyc:META_PWY-6369 inositol diphosphates biosynthesis
BioCyc:YEAST_PWY-6369 inositol pyrophosphates biosynthesis
BioCyc:HUMAN_PWY-6371 superpathway of inositol phosphate compounds
BioCyc:YEAST_PWY-6361 1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)
BioCyc:MOUSE_PWY-6362 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-1855191 Synthesis of IPs in the nucleus
Reactome:R-DRE-1483249 Inositol phosphate metabolism
Reactome:R-HSA-1855167 Synthesis of pyrophosphates in the cytosol
Reactome:R-RNO-1483249 Inositol phosphate metabolism
Reactome:R-DRE-1430728 Metabolism
Reactome:R-DRE-1855191 Synthesis of IPs in the nucleus
Reactome:R-HSA-1855191 Synthesis of IPs in the nucleus
Reactome:R-MMU-1855167 Synthesis of pyrophosphates in the cytosol
Reactome:R-RNO-1430728 Metabolism
Reactome:R-RNO-1855191 Synthesis of IPs in the nucleus
Reactome:R-DRE-1855167 Synthesis of pyrophosphates in the cytosol
Reactome:R-HSA-1430728 Metabolism
Reactome:R-HSA-1483249 Inositol phosphate metabolism
Reactome:R-MMU-1483249 Inositol phosphate metabolism
Reactome:R-RNO-1855167 Synthesis of pyrophosphates in the cytosol
PathBank:SMP0000011 Inositol Metabolism
PathBank:SMP0000462 Inositol Phosphate Metabolism
PathBank:SMP0002394 Inositol Phosphate Metabolism
PathBank:SMP0087349 Inositol Phosphate Metabolism
PathBank:SMP0087335 Inositol Metabolism
PathBank:SMP0012028 Phytate Biosynthesis