EC: 2.5.1.22

spermine synthase (S-adenosyl 3-(methylthio)propylamine:spermidine 3-aminopropyltransferase)

enzyme lambda metabolic reaction experiment
- [spermine synthase(Enzyme) wildtype]

S_Adenosylmethioninamine + Spermidine -> 5'_Deoxy_5'_(methylthio)adenosine + Spermine		 (( (( (( (cytosol * Vmspms) ) * A) ) * D) ) / (( (( (( (( (Kiaspms * Kdspms) ) * (1 + (S / Kisspms))) ) + (Kdspms * A)) ) + (( (Kaspms * (1 + (S / Kisspms))) ) * D)) ) + (A * D))) buffer: *
PH: 7
Temperature: 36
uniprot:P52788 [spermine synthase(Enzyme) wildtype]

S_Adenosylmethioninamine + Spermidine -> 5'_Deoxy_5'_(methylthio)adenosine + Spermine		 (( (Vmax * S) ) / (Km + S)) buffer: 0.1 M potassium phosphate, 5 mM dithiotreitol
PH: 7.4
Temperature: 37
uniprot:P52788 [spermine synthase(Enzyme) wildtype]

S_Adenosylmethioninamine + Spermidine -> Spermine + 5'_Deoxy_5'_(methylthio)adenosine		 (( (Vmax * S) ) / (Km + S)) buffer: 0.1 M potassium phosphate, 5 mM dithiotreitol
PH: 7.4
Temperature: 37

Pathways

pathway id name
BioCyc:META_BSUBPOLYAMSYN-PWY spermidine biosynthesis I
BioCyc:META_POLYAMINSYN3-PWY superpathway of polyamine biosynthesis II
BioCyc:ECO_POLYAMSYN-PWY superpathway of polyamine biosynthesis I
BioCyc:ECOL316407_ARG+POLYAMINE-SYN superpathway of arginine and polyamine biosynthesis
BioCyc:HUMAN_ARGSPECAT-PWY spermine biosynthesis
BioCyc:META_ARGSPECAT-PWY Spermine Syn
BioCyc:META_PWY0-1303 aminopropylcadaverine biosynthesis
BioCyc:META_POLYAMSYN-PWY superpathway of polyamine biosynthesis I
BioCyc:ECO_ARG+POLYAMINE-SYN superpathway of arginine and polyamine biosynthesis
BioCyc:YEAST_ARGSPECAT-PWY spermine and methylthioadenosine biosynthesis
BioCyc:MOUSE_ARGSPECAT-PWY spermine biosynthesis
BioCyc:META_PWY-6834 spermidine biosynthesis III
BioCyc:META_ARG+POLYAMINE-SYN superpathway of arginine and polyamine biosynthesis
BioCyc:ECO_BSUBPOLYAMSYN-PWY spermidine biosynthesis I
BioCyc:ECO_PWY0-1303 aminopropylcadaverine biosynthesis
BioCyc:MOUSE_ORNSPNANA-PWY spermine biosynthesis II
BioCyc:ECOL316407_BSUBPOLYAMSYN-PWY spermidine biosynthesis I
BioCyc:ECOL316407_PWY0-1303 aminopropylcadaverine biosynthesis
BioCyc:ECOL316407_POLYAMSYN-PWY superpathway of polyamine biosynthesis I
PathBank:SMP0000857 S-Adenosyl-L-Methionine Biosynthesis
PathBank:SMP0002053 Aminopropylcadaverine Biosynthesis
PathBank:SMP0002054 Spermidine Biosynthesis I
PathBank:SMP0002097 Spermidine Biosynthesis and Metabolism
Reactome:R-BTA-1430728 Metabolism
Reactome:R-BTA-71291 Amino acid and derivative metabolism
Reactome:R-HSA-351202 Metabolism of polyamines
Reactome:R-MMU-1430728 Metabolism
Reactome:R-MMU-351202 Metabolism of polyamines
Reactome:R-BTA-351202 Metabolism of polyamines
Reactome:R-HSA-71291 Amino acid and derivative metabolism
Reactome:R-MMU-71291 Amino acid and derivative metabolism
Reactome:R-HSA-1430728 Metabolism
WikiPathways:WP497 Urea cycle and metabolism of amino groups
PathBank:SMP0002307 beta-Alanine Metabolism
PathBank:SMP0000445 Spermidine and Spermine Biosynthesis