HI_1261 - Haemophilus influenzae Rd KW20

folylpolyglutamate synthase/dihydrofolate synthase (folC)

ATP-binding Folate biosynthesis Ligase Magnesium Metal-binding Nucleotide-binding One-carbon metabolism Reference proteome

> HI_1261 - Haemophilus influenzae Rd KW20 [folylpolyglutamate synthase/dihydrofolate synthase (folC)]
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统计信息
序列长度 0
疏水性残基 0
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Metadata

Organism Source: 71421 - Haemophilus influenzae Rd KW20
EC Number: 6.3.2.12 / 6.3.2.17
Cluster:
Registry Model:

Reactions

reaction id name note
KEGG:R00942 tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) ATP + Tetrahydrofolate + L-Glutamate <=> ADP + Orthophosphate + THF-L-glutamate
KEGG:R01654 10-formyltetrahydrofolate:L-glutamate ligase (ADP-forming) ATP + 10-Formyltetrahydrofolate + L-Glutamate <=> ADP + Orthophosphate + (6R)-10-Formyltetrahydropteroyldiglutamate
KEGG:R02237 7,8-dihydropteroate:L-glutamate ligase (ADP-forming) ATP + Dihydropteroate + L-Glutamate <=> ADP + Orthophosphate + Dihydrofolate
KEGG:R04241 tetrahydropteroyl-gamma-polyglutamate:L-glutamate gamma-ligase (ADP-forming) ATP + THF-polyglutamate(n) + L-Glutamate <=> ADP + Orthophosphate + THF-polyglutamate(n+1)
KEGG:R05197 10-formyltetrahydropteroyldiglutamate:L-glutamate gamma-ligase (ADP-forming) n-1 ATP + (6R)-10-Formyltetrahydropteroyldiglutamate + n-1 L-Glutamate <=> n-1 ADP + n-1 Orthophosphate + 10-Formyltetrahydrofolylpolyglutamate
BioCyc:RXN0-2921 METHYLENE-THF-GLU-N + GLT + ATP --> METHYLENE-THF-GLU-N + ADP + Pi
BioCyc:FORMYLTHFGLUSYNTH-RXN FORMYL-THF-GLU-N + GLT + ATP --> FORMYL-THF-GLU-N + ADP + Pi
BioCyc:RXN-6341 N5-Formyl-THF-Glu-N + GLT + ATP --> N5-Formyl-THF-Glu-N + ADP + Pi
BioCyc:FOLYLPOLYGLUTAMATESYNTH-RXN THF-GLU-N + GLT + ATP --> THF-GLU-N + ADP + Pi
BioCyc:DIHYDROFOLATESYNTH-RXN GLT + 7-8-DIHYDROPTEROATE + ATP --> PROTON + DIHYDROFOLATE + Pi + ADP
Rhea:RHEA:10581 (6S)-5,6,7,8-tetrahydrofolyl-(γ-L-Glu)(n) + L-glutamate + ATP => (6S)-5,6,7,8-tetrahydrofolyl-(γ-L-Glu)(n+1) + ADP + phosphate + H+
Rhea:RHEA:10582 (6S)-5,6,7,8-tetrahydrofolyl-(γ-L-Glu)(n+1) + ADP + phosphate + H+ => (6S)-5,6,7,8-tetrahydrofolyl-(γ-L-Glu)(n) + L-glutamate + ATP
Rhea:RHEA:10583 (6S)-5,6,7,8-tetrahydrofolyl-(γ-L-Glu)(n) + L-glutamate + ATP <=> (6S)-5,6,7,8-tetrahydrofolyl-(γ-L-Glu)(n+1) + ADP + phosphate + H+
Rhea:RHEA:23585 7,8-dihydropteroate + L-glutamate + ATP => 7,8-dihydrofolate + ADP + phosphate + H+
Rhea:RHEA:23586 7,8-dihydrofolate + ADP + phosphate + H+ => 7,8-dihydropteroate + L-glutamate + ATP
Rhea:RHEA:23587 7,8-dihydropteroate + L-glutamate + ATP <=> 7,8-dihydrofolate + ADP + phosphate + H+
Rhea:RHEA:51905 10-formyltetrahydrofolyl-(γ-L-Glu)(n) + L-glutamate + ATP => 10-formyltetrahydrofolyl-(γ-L-Glu)(n+1) + ADP + phosphate + H+
Rhea:RHEA:51906 10-formyltetrahydrofolyl-(γ-L-Glu)(n+1) + ADP + phosphate + H+ => 10-formyltetrahydrofolyl-(γ-L-Glu)(n) + L-glutamate + ATP
Rhea:RHEA:51907 10-formyltetrahydrofolyl-(γ-L-Glu)(n) + L-glutamate + ATP <=> 10-formyltetrahydrofolyl-(γ-L-Glu)(n+1) + ADP + phosphate + H+
Rhea:RHEA:51913 (6R)-5,10-methylenetetrahydrofolyl-(γ-L-Glu)(n) + L-glutamate + ATP => (6R)-5,10-methylenetetrahydrofolyl-(γ-L-Glu)(n+1) + ADP + phosphate + H+
Rhea:RHEA:51914 (6R)-5,10-methylenetetrahydrofolyl-(γ-L-Glu)(n+1) + ADP + phosphate + H+ => (6R)-5,10-methylenetetrahydrofolyl-(γ-L-Glu)(n) + L-glutamate + ATP
Rhea:RHEA:51915 (6R)-5,10-methylenetetrahydrofolyl-(γ-L-Glu)(n) + L-glutamate + ATP <=> (6R)-5,10-methylenetetrahydrofolyl-(γ-L-Glu)(n+1) + ADP + phosphate + H+

Pathways

pathway id name