XF_0071 - Xylella fastidiosa 9a5c

formamidopyrimidine DNA glycosylase

DNA damage DNA repair DNA-binding Glycosidase Hydrolase Lyase Metal-binding Multifunctional enzyme Zinc Zinc-finger

> XF_0071 - Xylella fastidiosa 9a5c [formamidopyrimidine DNA glycosylase]
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统计信息
序列长度 0
疏水性残基 0
极性残基 0
Legend

Metadata

Organism Source: 160492 - Xylella fastidiosa 9a5c
EC Number: 3.2.2.23 / 4.2.99.18
Cluster:
Registry Model:

Reactions

reaction id name note
BioCyc:4.2.99.18-RXN DNA-containing-abasic-Sites --> 3-terminal-unsaturated-sugars + 5-Phospho-terminated-DNAs + PROTON
BioCyc:RXN-20478 a-thymine-glycol-in-DNA + WATER --> a-DNA-3-alpha-beta-unsaturated-aldehyde + 5-Phospho-DNA + CPD-18012 + PROTON
BioCyc:RXN0-2601 Damaged-DNA-Pyrimidine + WATER --> a-DNA-3-alpha-beta-unsaturated-aldehyde + 5-Phospho-terminated-DNAs + Modified-Bases + PROTON Excision of the nucleobase lesion is a two-step process and involves formation of an enzyme-substrate Schiff base intermediate; subsequent DNA strand nicking occurs via a β-elimination leaving a 3'-terminal α,β-unsaturated aldehyde and a 5'-terminal phosphate. This reaction is catalysed by the Nth (HhH) family of bifunctional DNA glycosylases.
BioCyc:RXN-18435 DNA-With-GO + WATER --> CPD-12427 + 5-Phospho-terminated-DNAs + 3-Prime-Phosphate-Terminated-DNAs + CPD-21221 + 2 PROTON
BioCyc:RXN-21261 a-uracil-in-DNA-I + WATER --> a-DNA-3-alpha-beta-unsaturated-aldehyde + 5-Phospho-terminated-DNAs + URACIL + PROTON
BioCyc:RXN-21266 a-purine-base-lesion-in-DNA + WATER --> 3-Prime-Phosphate-Terminated-DNAs + 5-Phospho-terminated-DNAs + CPD-21221 + Modified-Bases Excision of the nucleobase lesion is a two-step process and involves formation of an enzyme-substrate Schiff base intermediate; subsequent DNA strand nicking occurs via a β,δ-elimination leaving a 3'-terminal phosphate and a 5'-terminal phosphate. This reaction is catalysed by the Fpg (MutM) family of bifunctional DNA glycosylases.
BioCyc:3.2.2.23-RXN DNA-containing-diamino-hydro-formamidops + WATER --> CPD-16491 + 5-Phospho-terminated-DNAs + 3-Prime-Phosphate-Terminated-DNAs + CPD-21221 + 2 PROTON
Rhea:RHEA:66593 2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA => a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H+
Rhea:RHEA:66594 a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H+ => 2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA
Rhea:RHEA:66595 2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA <=> a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H+

Pathways

pathway id name