数据之源，洞见之始

3D-structure Acyltransferase Direct protein sequencing Glutathione biosynthesis Hydrolase Periplasm Protease Reference proteome Signal Transferase Zymogen

Periplasm

统计信息

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Metadata

Organism Source: 83333 - Escherichia coli K-12
EC Number: 2.3.2.2 / 3.4.19.13
Cluster:
Registry Model:

Reactions

reaction id	name	note
KEGG:R00494	glutathione gamma-glutamylaminopeptidase	Glutathione + H2O <=> Cys-Gly + L-Glutamate
KEGG:R01262	glutathione:L-amino-acid 5-glutamyltransferase	Glutathione + L-Amino acid <=> Cys-Gly + (5-L-Glutamyl)-L-amino acid
KEGG:R01687	(5-L-glutamyl)-peptide:taurine 5-glutamyltransferase	(5-L-Glutamyl)-peptide + Taurine <=> Peptide + 5-L-Glutamyl-taurine
KEGG:R03867	(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase	Leukotriene C4 + Amino acid <=> Leukotriene D4 + 5-L-Glutamyl amino acid
KEGG:R03916	(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase	R-S-Glutathione + H2O <=> R-S-Cysteinylglycine + L-Glutamate
KEGG:R03970	(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase	3-Cyano-L-alanine + L-Glutamate <=> gamma-Glutamyl-beta-cyanoalanine + H2O
KEGG:R03971	gamma-glutamyl-beta-aminopropiononitrile amidohydrolase	3-Aminopropiononitrile + L-Glutamate <=> gamma-Glutamyl-beta-aminopropiononitrile + H2O
KEGG:R04159	(5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase	(5-L-Glutamyl)-peptide + Amino acid <=> Peptide + 5-L-Glutamyl amino acid
KEGG:R04935	(5-L-glutamyl)-peptide:Se-methylselenocysteine 5-glutamyltransferase	(5-L-Glutamyl)-peptide + Se-Methyl-L-selenocysteine <=> Peptide + gamma-Glutamyl-Se-methylselenocysteine
BioCyc:RXN-12618	GLUTATHIONE + WATER --> CYS-GLY + GLT
BioCyc:RXN-18092	GLUTATHIONE + GLYCYLGLYCINE --> CPD-19395 + CYS-GLY
BioCyc:GAMMA-GLUTAMYLTRANSFERASE-RXN	5-L-GLUTAMYL-PEPTIDE + Amino-Acids --> 5-L-GLUTAMYL-AMINO-ACID + Peptides-holder + 2 PROTON
Rhea:RHEA:23905	an N-terminal (5-L-glutamyl)-[peptide] + an α-amino acid => 5-L-glutamyl amino acid + an N-terminal L-α-aminoacyl-[peptide]
Rhea:RHEA:23906	5-L-glutamyl amino acid + an N-terminal L-α-aminoacyl-[peptide] => an N-terminal (5-L-glutamyl)-[peptide] + an α-amino acid
Rhea:RHEA:23907	an N-terminal (5-L-glutamyl)-[peptide] + an α-amino acid <=> 5-L-glutamyl amino acid + an N-terminal L-α-aminoacyl-[peptide]
Rhea:RHEA:28808	glutathione + H2O => L-cysteinylglycine + L-glutamate
Rhea:RHEA:28809	L-cysteinylglycine + L-glutamate => glutathione + H2O
Rhea:RHEA:28810	glutathione + H2O <=> L-cysteinylglycine + L-glutamate
Rhea:RHEA:59469	an S-substituted glutathione + H2O => an S-substituted L-cysteinylglycine + L-glutamate
Rhea:RHEA:59470	an S-substituted L-cysteinylglycine + L-glutamate => an S-substituted glutathione + H2O
Rhea:RHEA:59471	an S-substituted glutathione + H2O <=> an S-substituted L-cysteinylglycine + L-glutamate
BioCyc:RXN-19578	CPDQT-434 + WATER --> CPD-21170 + GLT	Hydrolysis of a γ-glutamyl bond.A lysosomal or secreted, thiol-dependent peptidase, most active at acidic pH.Commonly studied with folylpoly-γ-glutamate as substrate, with which the initial cleavagemay release glutamate or poly-γ-glutamate of two or more residues, according to the speciesof origin of the enzyme. Final products are pteroyl-α-glutamate (folic acid) and free glutamate.Highly specific for the γ-glutamyl bond, but not for the C-terminal amino acid (leaving group).Action on γ-glutamyl bonds is independent of an N-terminal pteroyl moiety, but it isnot known whether an N-terminal γ-Glu residue can be hydrolysed.Type example of peptidase family C26. Formerly EC 3.4.22.12
BioCyc:RXN-9157	GLUTATHIONE + CPD-9699 --> CPD-9700 + CYS-GLY
BioCyc:RXN-19607	CPD-21162 + WATER --> CPD-21201 + GLT
BioCyc:RXN-19602	CPD-21194 + WATER --> CPD-21195 + GLT
BioCyc:RXN66-336	LEUKOTRIENE-C4 + Amino-Acids-20 --> 5-L-GLUTAMYL-L-AMINO-ACID + CPD66-21
BioCyc:RXN-19574	CPD-21172 + WATER --> CPD-21171 + GLT	Hydrolysis of a γ-glutamyl bond.A lysosomal or secreted, thiol-dependent peptidase, most active at acidic pH.Commonly studied with folylpoly-γ-glutamate as substrate, with which the initial cleavagemay release glutamate or poly-γ-glutamate of two or more residues, according to the speciesof origin of the enzyme. Final products are pteroyl-α-glutamate (folic acid) and free glutamate.Highly specific for the γ-glutamyl bond, but not for the C-terminal amino acid (leaving group).Action on γ-glutamyl bonds is independent of an N-terminal pteroyl moiety, but it isnot known whether an N-terminal γ-Glu residue can be hydrolysed.Type example of peptidase family C26. Formerly EC 3.4.22.12
BioCyc:RXN-13675	CPD-14704 + WATER --> CPD-14705 + GLT
BioCyc:RXN-19608	S-METHYLGLUTATHIONE + WATER --> CPD-21202 + GLT
BioCyc:RXN-6641	S-Substituted-Glutathione + WATER --> CPD-6262 + GLT
BioCyc:RXN-6601	GLUTATHIONE + Amino-Acids-20 --> 5-L-GLUTAMYL-L-AMINO-ACID + CYS-GLY
BioCyc:RXN-19572	CPD-21160 + WATER --> CPD-21166 + GLT	Hydrolysis of a γ-glutamyl bond.A lysosomal or secreted, thiol-dependent peptidase, most active at acidic pH.Commonly studied with folylpoly-γ-glutamate as substrate, with which the initial cleavagemay release glutamate or poly-γ-glutamate of two or more residues, according to the speciesof origin of the enzyme. Final products are pteroyl-α-glutamate (folic acid) and free glutamate.Highly specific for the γ-glutamyl bond, but not for the C-terminal amino acid (leaving group).Action on γ-glutamyl bonds is independent of an N-terminal pteroyl moiety, but it isnot known whether an N-terminal γ-Glu residue can be hydrolysed.Type example of peptidase family C26. Formerly EC 3.4.22.12
BioCyc:RXN-19604	CPD-21199 + WATER --> CPD-21107 + GLT
BioCyc:RXN-19732	CPD-21344 + WATER --> CPD-21345 + GLT
BioCyc:RXN-19627	CPD-21241 + WATER --> CPD-21134 + GLT
BioCyc:RXN-22398	CPD-24389 + WATER --> CPD-24391 + GLT

Pathways

pathway id	name