thyA - Escherichia coli K-12
Thymidylate synthase
> thyA - Escherichia coli K-12 [Thymidylate synthase]
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统计信息
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Metadata
Organism Source: 83333 - Escherichia coli K-12
EC Number: 2.1.1.45
Cluster:
Registry Model:
Reactions
| reaction id | name | note |
|---|---|---|
| KEGG:R02101 | 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase | dUMP + 5,10-Methylenetetrahydrofolate <=> Dihydrofolate + dTMP |
| BioCyc:THYMIDYLATESYN-RXN | METHYLENE-THF-GLU-N + DUMP --> TMP + DIHYDROFOLATE-GLU-N | |
| Rhea:RHEA:12105 | dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate => 7,8-dihydrofolate + dTMP | |
| Rhea:RHEA:12106 | 7,8-dihydrofolate + dTMP => dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate | |
| Rhea:RHEA:12107 | dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate <=> 7,8-dihydrofolate + dTMP |
Pathways
| pathway id | name |
|---|---|
| BioCyc:META_1CMET2-PWY | N10-formyl-tetrahydrofolate biosynthesis |
| BioCyc:META_PWY-7211 | superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis |
| BioCyc:ECO_PWY-7187 | pyrimidine deoxyribonucleotides de novo biosynthesis II |
| BioCyc:ECOL316407_PWY-7187 | pyrimidine deoxyribonucleotides de novo biosynthesis II |
| BioCyc:ECOL316407_PWY-7184 | pyrimidine deoxyribonucleotides de novo biosynthesis I |
| BioCyc:META_PWY-7184 | pyrimidine deoxyribonucleotides de novo biosynthesis I |
| BioCyc:ECO_PWY-7184 | pyrimidine deoxyribonucleotides de novo biosynthesis I |
| BioCyc:ECO_1CMET2-PWY | N10-formyl-tetrahydrofolate biosynthesis |
| BioCyc:META_PWY-7187 | pyrimidine deoxyribonucleotides de novo biosynthesis II |
| BioCyc:ECO_PWY-7211 | superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis |
| BioCyc:ECOL316407_1CMET2-PWY | formylTHF biosynthesis |
| PathBank:SMP0000959 | Pyrimidine Metabolism |
| PathBank:SMP0001750 | One Carbon Pool by Folate |