metL - Escherichia coli K-12

Bifunctional aspartokinase/homoserine dehydrogenase 2

Amino-acid biosynthesis ATP-binding Direct protein sequencing Kinase Lysine biosynthesis Metal-binding Methionine biosynthesis Multifunctional enzyme NAD NADP Nucleotide-binding Oxidoreductase Reference proteome Sodium Threonine biosynthesis Transferase

> metL - Escherichia coli K-12 [Bifunctional aspartokinase/homoserine dehydrogenase 2]
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统计信息
序列长度 0
疏水性残基 0
极性残基 0
Legend

Metadata

Organism Source: 83333 - Escherichia coli K-12
EC Number: 1.1.1.3 / 2.7.2.4
Cluster:
Registry Model:

Reactions

reaction id name note
KEGG:R00480 ATP:L-aspartate 4-phosphotransferase ATP + L-Aspartate <=> ADP + 4-Phospho-L-aspartate
KEGG:R01773 L-homoserine:NAD+ oxidoreductase NADP+ (see R01775)
KEGG:R01775 L-homoserine:NADP+ oxidoreductase NAD+ (see R01773)
BioCyc:ASPARTATEKIN-RXN L-ASPARTATE + ATP --> L-BETA-ASPARTYL-P + ADP
BioCyc:HOMOSERDEHYDROG-RXN L-ASPARTATE-SEMIALDEHYDE + NADH-P-OR-NOP + PROTON --> HOMO-SER + NAD-P-OR-NOP
Rhea:RHEA:15758 L-homoserine + NAD+ => L-aspartate 4-semialdehyde + NADH + H+
Rhea:RHEA:15759 L-aspartate 4-semialdehyde + NADH + H+ => L-homoserine + NAD+
Rhea:RHEA:15760 L-homoserine + NAD+ <=> L-aspartate 4-semialdehyde + NADH + H+
Rhea:RHEA:15762 L-homoserine + NADP+ => L-aspartate 4-semialdehyde + NADPH + H+
Rhea:RHEA:15763 L-aspartate 4-semialdehyde + NADPH + H+ => L-homoserine + NADP+
Rhea:RHEA:15764 L-homoserine + NADP+ <=> L-aspartate 4-semialdehyde + NADPH + H+
Rhea:RHEA:23777 L-aspartate + ATP => 4-phospho-L-aspartate + ADP
Rhea:RHEA:23778 4-phospho-L-aspartate + ADP => L-aspartate + ATP
Rhea:RHEA:23779 L-aspartate + ATP <=> 4-phospho-L-aspartate + ADP

Pathways

pathway id name
BioCyc:META_PWY0-781 aspartate superpathway
BioCyc:ECOL316407_P4-PWY superpathway of lysine, threonine and methionine biosynthesis I
BioCyc:ECOL316407_METSYN-PWY homoserine and methionine biosynthesis
BioCyc:ECOL316407_PWY0-781 aspartate superpathway
BioCyc:META_HOMOSERSYN-PWY L-homoserine biosynthesis
BioCyc:ECO_P4-PWY superpathway of L-lysine, L-threonine and L-methionine biosynthesis I
BioCyc:ECOL316407_DAPLYSINESYN-PWY lysine biosynthesis I
BioCyc:ECOL316407_MET-SAM-PWY superpathway of S-adenosyl-L-methionine biosynthesis
BioCyc:META_PWY-5347 superpathway of L-methionine biosynthesis (transsulfuration)
BioCyc:ECO_MET-SAM-PWY superpathway of S-adenosyl-L-methionine biosynthesis
BioCyc:ECO_THRESYN-PWY superpathway of L-threonine biosynthesis
BioCyc:ECOL316407_HOMOSERSYN-PWY homoserine biosynthesis
BioCyc:ECOL316407_THRESYN-PWY threonine biosynthesis
BioCyc:META_METSYN-PWY superpathway of L-homoserine and L-methionine biosynthesis
BioCyc:META_P4-PWY superpathway of L-lysine, L-threonine and L-methionine biosynthesis I
BioCyc:META_THRESYN-PWY superpathway of L-threonine biosynthesis
BioCyc:META_MET-SAM-PWY superpathway of S-adenosyl-L-methionine biosynthesis
BioCyc:META_PWY-3001 superpathway of L-isoleucine biosynthesis I
BioCyc:ECO_HOMOSERSYN-PWY L-homoserine biosynthesis
BioCyc:ECO_PWY0-781 aspartate superpathway
BioCyc:ECO_METSYN-PWY superpathway of L-homoserine and L-methionine biosynthesis
PathBank:SMP0000834 Methionine Biosynthesis
PathBank:SMP0000837 Threonine Biosynthesis
PathBank:SMP0000992 Secondary Metabolites: Threonine Biosynthesis from Aspartate