thiE-1 - Streptococcus pneumoniae TIGR4

thiamine-phosphate pyrophosphorylase

Magnesium Metal-binding Reference proteome Thiamine biosynthesis Transferase

> thiE-1 - Streptococcus pneumoniae TIGR4 [thiamine-phosphate pyrophosphorylase]
请在左侧输入序列并点击“更新视图”...



统计信息
序列长度 0
疏水性残基 0
极性残基 0
Legend

Metadata

Organism Source: 170187 - Streptococcus pneumoniae TIGR4
EC Number: 2.5.1.3 / 2.5.1.3
Cluster:
Registry Model:

Reactions

reaction id name note
KEGG:R03223 2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:4-methyl-5-(2-phosphoethyl)-thiazole 2-methyl-4-aminopyridine-5-methenyltransferase 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 4-Methyl-5-(2-phosphooxyethyl)thiazole <=> Diphosphate + Thiamin monophosphate
KEGG:R10712 2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate 2-methyl-4-aminopyrimidine-5-methenyltransferase 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate <=> Thiamin monophosphate + Diphosphate + CO2
KEGG:R11312 C04752 + C20246<=>C00013 + C01081 + C00011 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate <=> Diphosphate + Thiamin monophosphate + CO2
BioCyc:THI-P-SYN-RXN THZ-P + AMINO-HYDROXYMETHYL-METHYLPYRIMIDINE-PP + PROTON --> THIAMINE-P + PPI
BioCyc:RXN-12610 CPD-13576 + AMINO-HYDROXYMETHYL-METHYLPYRIMIDINE-PP + 2 PROTON --> THIAMINE-P + CARBON-DIOXIDE + PPI
BioCyc:RXN-12611 thiamin phosphate synthase
Rhea:RHEA:22329 4-methyl-5-(2-phosphooxyethyl)-thiazole + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H+ => thiamine phosphate + diphosphate
Rhea:RHEA:22330 thiamine phosphate + diphosphate => 4-methyl-5-(2-phosphooxyethyl)-thiazole + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H+
Rhea:RHEA:22331 4-methyl-5-(2-phosphooxyethyl)-thiazole + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H+ <=> thiamine phosphate + diphosphate
Rhea:RHEA:47845 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H+ => thiamine phosphate + CO2 + diphosphate Published in: "Biosynthesis of Thiamin I: The Function of the thiE Gene Product." Backstrom AD, McMordie RAS, Begley TP J Am Chem Soc 117: 2351-2352 (1995).
Rhea:RHEA:47846 thiamine phosphate + CO2 + diphosphate => 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H+ Published in: "Biosynthesis of Thiamin I: The Function of the thiE Gene Product." Backstrom AD, McMordie RAS, Begley TP J Am Chem Soc 117: 2351-2352 (1995).
Rhea:RHEA:47847 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H+ <=> thiamine phosphate + CO2 + diphosphate Published in: "Biosynthesis of Thiamin I: The Function of the thiE Gene Product." Backstrom AD, McMordie RAS, Begley TP J Am Chem Soc 117: 2351-2352 (1995).
Rhea:RHEA:47849 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H+ => thiamine phosphate + CO2 + diphosphate Published in: "Biosynthesis of Thiamin I: The Function of the thiE Gene Product." Backstrom AD, McMordie RAS, Begley TP J Am Chem Soc 117: 2351-2352 (1995).
Rhea:RHEA:47850 thiamine phosphate + CO2 + diphosphate => 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H+ Published in: "Biosynthesis of Thiamin I: The Function of the thiE Gene Product." Backstrom AD, McMordie RAS, Begley TP J Am Chem Soc 117: 2351-2352 (1995).
Rhea:RHEA:47851 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H+ <=> thiamine phosphate + CO2 + diphosphate Published in: "Biosynthesis of Thiamin I: The Function of the thiE Gene Product." Backstrom AD, McMordie RAS, Begley TP J Am Chem Soc 117: 2351-2352 (1995).

Pathways

pathway id name