citrulline biosynthesis

Brandriss MC, Magasanik B. Genetics and physiology of proline utilization in Saccharomyces cerevisiae: enzyme induction by proline. J Bacteriol. 1979 Nov;140(2):498–503. doi: 10.1128/jb.140.2.498-503.1979.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Manganese(2+)

Formula: Mn (54.938046)

CAS ID: 7439-96-5

Urea

Formula: CH4N2O (60.0323614)

CAS ID: 57-13-6

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

L-argininium(1+)

Formula: C6H15N4O2 (175.119495)

CAS ID: 17806-42-7

2-oxoglutarate(2-)

Formula: C5H4O5 (144.00587339999998)

CAS ID: 64-15-3

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
1.2.1.41 glutamate-5-semialdehyde dehydrogenase L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)
1.5.5.2 proline dehydrogenase L-proline:quinone oxidoreductase
2.1.3.3 ornithine carbamoyltransferase carbamoyl-phosphate:L-ornithine carbamoyltransferase
2.6.1.13 ornithine aminotransferase L-ornithine:2-oxo-acid aminotransferase
2.7.2.11 glutamate 5-kinase ATP:L-glutamate 5-phosphotransferase
3.5.1.2 glutaminase L-glutamine amidohydrolase
3.5.3.1 arginase L-arginine amidinohydrolase
4.3.3.6 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) D-ribose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5'-phosphate-lyase


Proteins

Protein ID name full name
P00812 CAR1 Arginase
P05150 ARG3 Ornithine carbamoyltransferase
P07991 CAR2 Ornithine aminotransferase
P09368 PUT1 Proline dehydrogenase, mitochondrial
P32264 PRO1 Glutamate 5-kinase
P54885 PRO2 Gamma-glutamyl phosphate reductase
Q03144 SNO1 Pyridoxal 5'-phosphate synthase subunit SNO1
Q03148 SNZ1 Pyridoxal 5'-phosphate synthase subunit SNZ1