secologanin and strictosidine biosynthesis
Miettinen K, Dong L, Navrot N, Schneider T, Burlat V, Pollier J, Woittiez L, van der Krol S, Lugan R, Ilc T, Verpoorte R, Oksman-Caldentey K, Martinoia E, Bouwmeester H, Goossens A, Memelink J, Werck-Reichhart D. Erratum: Corrigendum: The seco-iridoid pathway from Catharanthus roseus. Nature Communications. 2014 Jun 24;5(1):4175. doi: 10.1038/ncomms5175.; Geu-Flores F, Sherden NH, Courdavault V, Burlat V, Glenn WS, Wu C, Nims E, Cui Y, O’Connor SE. An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis. Nature. 2012 Nov 21;492(7427):138–42. doi: 10.1038/nature11692.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 1.14.14.83 | geraniol 8-hydroxylase | geraniol,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating) | |
| 1.14.14.85 | 7-deoxyloganate 7-hydroxylase | 7-deoxyloganate,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (7alpha-hydroxylating) | |
| 1.3.1.122 | (S)-8-oxocitronellyl enol synthase | (S)-8-oxocitronellyl enol:NAD(P)+ oxidoreductase | |
| 2.1.1.50 | loganate O-methyltransferase | S-adenosyl-L-methionine:loganate 11-O-methyltransferase | |
| 2.4.1.323 | 7-deoxyloganetic acid glucosyltransferase | UDP-alpha-D-glucose:7-deoxyloganetate O-D-glucosyltransferase | |
| 3.5.99.13 | strictosidine synthase | 3-alpha(S)-strictosidine tryptamine-hydrolase (secologanin-forming) | |
| 4.1.1.105 | L-tryptophan decarboxylase | L-tryptophan carboxy-lyase | |
| 4.1.1.28 | aromatic-L-amino-acid decarboxylase | Aromatic-L-amino-acid carboxy-lyase |
Proteins
| Protein ID | name | full name |
|---|